Dexter O'Kane is a family man who becomes an assassin after the death of his wife and son, a failing business, and witnessing a murder that unravels his simple life. Recruiting best friend and business partner John Wood to be his partner in crime, Dexter is on the hunt for a serial killer who's wreaking havoc in the small blue collar town of LeClaire, Missouri.

Dexter's estranged father is getting out of prison. What follows George O'Kane will send Dexter back into the killing game, a game he's trying to leave behind. The Buffones, an Italian crime family living in the shadows of LeClaire, are looking for payment, a gambling debt owed before Dexter's father left for prison. Dexter and his partner in crime John Woods must find a way to pay the debts, save his father, and end the evil Buffone family...or die trying.