In 2015 a research team at UC Riverside found that soybean oil consumption induces obesity, diabetes, insulin resistance, and fatty liver in mice. Now, a new study by the same team shows that oil could also affect genes in the brain related to conditions like autism, Alzheimer's disease, anxiety, and depression. Listen in this week as Dee discusses the details of this study and how the changes in microbiome caused by soybean oil consumption are linked to negative iimpact on brain function.

Reference:

Martinez-Lomeli, J., Deol, P., Deans, J. R., Jiang, T., Ruegger, P., Borneman, J., & Sladek, F. M. (2023). Impact of various high fat diets on gene expression and the microbiome across the mouse intestines. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-49555-7

A recent study conducted at the University of Texas MD Anderson Cancer Center showed that patients with a history of colorectal cancer who added a cup of navy beans daily to their regular meals saw positive changes in their gut microbiome after just 4 weeks. Listen in this week as Dee discusses the details of this study and how the changes in microbiome aid in colorectal cancer prevention and treatment.

Reference:

Zhang, X., Irajizad, E., Hoffman, K. L., Fahrmann, J. F., Li, F., Seo, Y. D., Browman, G. J., Dennison, J. B., Vykoukal, J., Luna, P. N., Siu, W., Wu, R., Murage, E., Ajami, N. J., Mcquade, J. L., Wargo, J. A., Long, J. P., Do, K.-A., Lampe, J. W., … Daniel, C. R.. (2023). Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: Insights from the BE GONE trial. Ebiomedicine, 98, 104873. https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00439-5/fulltext

Autophagy is a natural biochemical self-preservation process whereby the body cleans out damaged cells in order to regenerate newer, healthier cells. There are certain diet and lifestyle factors that aid or inhibit autophagy, leading either to improved health or accelerated degeneration. Listen in this week as Dee discusses the mechanisms of autophagy and the best ways to ensure its optimal benefits.

Reference:

Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R. I., Simon, A. K., Bjedov, I., Palikaras, K., Simonsen, A., Johansen, T., Tavernarakis, N., Rubinsztein, D. C., Partridge, L., Kroemer, G., Labbadia, J., & Fang, E. F. (2021). Autophagy in healthy aging and disease. Nature Aging, 1(8), 634–650. https://www.nature.com/articles/s43587-021-00098-4#