Difficult to Treat Depression

A Carlat Guide

By: Chris Aiken

Narrated by: Chris Aiken, Kellie Newsome

Treatment-resistant depression challenges even the most experienced clinicians. This practical book bridges the gap between research and clinical application, offering experienced psychiatrists a structured approach to patients who haven't responded to conventional treatments.

You'll find:

How to personalize treatment by subtype, including: Bipolar, mixed, psychotic, vascular, inflammatory, postpartum, seasonal, and trauma-related depression

Basic and advanced augmentation strategies: Lithium, antipsychotics, thyroid, pramipexole, celecoxib, dextromethorphan, amantadine, minocycline, and d-cycloserine

Advanced somatic treatments including ECT, TMS, SNT (SAINT) TMS, ketamine/esketamine, and emerging neuromodulation therapies

Natural therapies: Lightbox, omega-3, probiotics, methylfolate, SAMe, and vitamin E

Psychotherapeutic and lifestyle approaches for treatment-resistant populations

©2025 Carlat Publishing (P)2025 Chris Aiken

Brilliant!

You won’t regret buying this book! So full of useful clinical pearls. I have really enjoyed it