In this lesson on glycoprotein (GP) IIb/IIIa (GPIIb/IIIa) inhibitors, you’ll learn the high-yield, test-relevant concepts behind the adjunct antiplatelet drug therapy used in the acute management of patients experiencing an acute myocardial infarction (AMI; NSTEMI, STEMI) and undergoing PCI or coronary stent placement. In this lecture from This is Why, Dr. Busti will break down how platelet aggregation inhibitors work, when they’re used clinically, and the key differences between tirofiban and eptifibatide —so you can apply the “why” behind therapy (not just memorize drug names).

You’ll learn how to:

- The GPIIb/IIIa receptor and how blocking it reduces platelet activation

- Where GPIIb/IIIa inhibitors fit in clinical practice

- High-yield uses: acute coronary syndrome (ACS) and PCI/stents

- Major adverse effects (including bleeding) and top safety pearls

The goal = make medical education easy and clinically relevant.

Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/gpiibiiia-inhibitors-tirofiban-eptifibatide-antiplatelet-pharmacology-review

Get more with a free membership at https://www.thisiswhy.health/

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#gpiibiiiainhibitors #tirofiban #antiplateletpharmacology #eptifibatide #drbusti

Disclaimer:

This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

In this lesson on P2Y12 inhibitors (ADP inhibitors), you’ll learn the high-yield, test-relevant concepts behind the most common antiplatelet drugs used in cardiovascular care. In this lecture from This is Why, Dr. Busti will break down how platelet aggregation inhibitors work, when they’re used clinically, and the key differences between clopidogrel (Plavix), prasugrel (Effient), ticagrelor (Brilinta), and cangrelor (Kengreal)—so you can apply the “why” behind therapy (not just memorize drug names).

You’ll learn how to:

- The P2Y12 (ADP) receptor and how blocking it reduces platelet activation

- Where P2Y12 inhibitors fit in dual antiplatelet therapy (DAPT)

- High-yield uses: acute coronary syndrome (ACS), PCI/stents, and secondary prevention

- Major adverse effects (including bleeding) and top safety pearls

- The exam-favorite comparisons: prodrug activation, onset/offset, reversibility, and IV vs PO options

The goal = make medical education easy and clinically relevant.

Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/p2y12-adp-inhibitors-antiplatelet-pharmacology-review

Get more with a free membership at https://www.thisiswhy.health/

- Access free downloads from our videos

- Access deep dive content from Dr. Busti

- Organize content via playlists & collections

- Join live Q&A

- Receive member newsletters

- Coupons & discounts for exam prep resources

If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#p2y12inhibitors #clopidogrel #antiplateletpharmacology #ticagrelor #drbusti

Disclaimer:

This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

Master Aspirin (ASA) fast with this Antiplatelet Pharmacology Made Easy & Relevant lecture. In this lecture from This is Why, Dr. Busti will make sure you learn how acetylsalicylic acid works as an antiplatelet drug, including COX-1 inhibition, decreased thromboxane A2 (TXA2), and reduced platelet aggregation—plus the key clinical takeaways for MI prevention, stroke prevention, and secondary prevention.

You’ll learn how to:
- Aspirin mechanism of action (COX inhibitor → ↓ TXA2 → ↓ platelet aggregation)
- Why aspirin is different from other NSAIDs in antiplatelet therapy
- High-yield uses in cardiovascular pharmacology (MI/stroke prevention)
- Side effects, contraindications, and safety pearls you need for exams

The goal = make medical education easy and clinically relevant.

👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/aspirin-asa-salicylic-acid-antiplatelet-pharmacology-review

👉 Get more with a free membership at https://www.thisiswhy.health/
- Access free downloads from our videos
- Access deep dive content from Dr. Busti
- Organize content via playlists & collections
- Join live Q&A
- Receive member newsletters
- Coupons & discounts for exam prep resources

👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#aspirin #asa #aspirinpharmacology #antiplateletdrugspharmacology #drbusti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

In this lecture from This is Why, Dr. Busti will break down Heparin (UFH) and Low-Molecular-Weight Heparins (LMWHs), such as enoxaparin (Lovenox) and dalteparin (Fragmin), with a clear, clinically relevant approach. If you’re studying anticoagulation or need a fast refresher on anticoagulants, this video is for you.

In this lesson, you’ll learn:
- Heparin mechanism of action (UFH vs LMWH) + how they work in the clotting cascade
- Monitoring & labs: aPTT/PTT for UFH, anti–Factor Xa concepts for LMWH
- Dosing/administration pearls (IV vs SQ, onset/offset, bridging basics)
- Adverse effects & safety: bleeding, HIT (heparin-induced thrombocytopenia), contraindications
- Clinical comparisons: heparin vs enoxaparin, when each is commonly used

The goal = make medical education easy and clinically relevant.

👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/heparins-ufh-lmwh-anticoagulants-pharmacology-review

👉 Get more with a free membership at https://www.thisiswhy.health/
- Access free downloads from our videos
- Access deep dive content from Dr. Busti
- Organize content via playlists & collections
- Join live Q&A
- Receive member newsletters
- Coupons & discounts for exam prep resources

👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#UnfractionatedHeparin #LowMolecularWeightHeparin #Enoxaparin #Anticoagulation #drbusti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition, and never delay care because of educational content.

Warfarin (Vitamin K Antagonist; VKA) doesn’t have to be confusing. In this lecture from This is Why, Dr. Busti will explain warfarin's (Coumadin) pharmacology in a simple, clinically relevant way. It is perfect for anyone reviewing anticoagulation.

You’ll learn how to:
- Mechanism of action: how warfarin works as a vitamin K antagonist (VKA) (VKOR inhibition)
- What PT/INR measures and why INR monitoring matters
- How to start warfarin dosing (and what affects dose response)
- Bridging with heparin/LMWH (warfarin bridge / heparin bridge) and when it’s needed
- High-yield warfarin interactions (CYP2C9 inhibitors/inducers) + vitamin K foods
- Warfarin reversal basics (including vitamin K reversal)

The goal = make medical education easy and clinically relevant.

👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/warfarin-vka-coumadin-anticoagulants-pharmacology-review

👉 Get more with a free membership at https://www.thisiswhy.health/
- Access free downloads from our videos
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- Join live Q&A
- Receive member newsletters
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👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#WarfarinPharmacology #VitaminKAntagonist #WarfarinDosing #WarfarinInteractions #drbusti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

Factor Xa inhibitors (DOACs) made easy—fast, clear, and clinically relevant. In this lecture from This is Why, Dr. Busti will break down direct oral anticoagulants (DOACs) and how Factor Xa inhibitors work, with relevance.

You’ll learn how to:
- What Factor Xa inhibitors do (mechanism of action)
- Key drugs: Apixaban (Eliquis), Rivaroxaban (Xarelto), Edoxaban (Savaysa)
- Common indications: Afib stroke prevention, DVT/PE treatment
- Major adverse effects and safety: bleeding risk, interactions, and monitoring pearls
- Reversal overview: What to know + when it matters

The goal = make medical education easy and clinically relevant.

👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/doac-factor-xa-inhibitors-anticoagulants-pharmacology-review

👉 Get more with a free membership at https://www.thisiswhy.health/
- Access free downloads from our videos
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- Organize content via playlists & collections
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- Receive member newsletters
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👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#FactorXaInhibitors #DOACs #Anticoagulation #Apixaban #drbusti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

Direct Thrombin Inhibitors (DTIs) made simple and clinically relevant! In this lecture from This is Why, Dr. Busti will help you master direct thrombin (Factor IIa) inhibitors—including the oral DTI dabigatran (Pradaxa) and key parenteral DTIs like bivalirudin (and where argatroban fits clinically, especially in the acute care setting)

You’ll learn how to:
- Where direct thrombin inhibitors work in the coagulation cascade
- How dabigatran works (mechanism of action), major indications, and high-yield adverse effects
- What to monitor, common drug interactions, and who is at higher bleeding risk
- Dabigatran reversal with idarucizumab (Praxbind)
- PCI anticoagulation and how DTIs show up in clinical practice (including HIT treatment concepts)

The goal = make medical education easy and clinically relevant.

👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/direct-thrombin-inhibitors-DTI-doac-anticoagulants-pharmacology-review

👉 Get more with a free membership at https://www.thisiswhy.health/
- Access free downloads from our videos
- Access deep dive content from Dr. Busti
- Organize content via playlists & collections
- Join live Q&A
- Receive member newsletters
- Coupons & discounts for exam prep resources

👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#directthrombinInhibitors #DTIpharmacology #DabigatranPharmacology #Anticoagulation #drbusti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.

In this lecture from This is Why, Dr. Busti will make Community-Acquired Pneumonia (CAP) simple, practical, and clinically relevant—so you can confidently recognize CAP, assess severity, and choose the right pneumonia treatment.

What you’ll learn:

- How to approach CAP pneumonia like a clinician: presentation, diagnosis, and key differentials

- How to assess severity using CURB-65 and the Pneumonia Severity Index (PSI score)

- How to decide outpatient pneumonia vs inpatient pneumonia management

- How to choose CAP antibiotics with guideline-based empiric antibiotics pneumonia selection

- What “atypical coverage” means (and when you need it)

- Common pitfalls (including aspiration pneumonia vs CAP) and how to avoid them

The goal = make medical education easy and clinically relevant.

Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/community-acquired-pneumonia-cap-treatment-guidelines

Get more with a free membership at https://www.thisiswhy.health/

- Access free downloads from our videos

- Access deep dive content from Dr. Busti

- Organize content via playlists & collections

- Join live Q&A

- Receive member newsletters

- Coupons & discounts for exam prep resources

If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.

Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!

#CommunityAcquiredPneumonia #CAP #PneumoniaTreatment #PneumoniaGuidelines #drbusti

Disclaimer:

This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.