Direct Thrombin inhibitors (DTI): Pharmacology Made Easy & Relevant

Direct Thrombin Inhibitors (DTIs) made simple and clinically relevant! In this lecture from This is Why, Dr. Busti will help you master direct thrombin (Factor IIa) inhibitors—including the oral DTI dabigatran (Pradaxa) and key parenteral DTIs like bivalirudin (and where argatroban fits clinically, especially in the acute care setting)

You’ll learn how to:
- Where direct thrombin inhibitors work in the coagulation cascade
- How dabigatran works (mechanism of action), major indications, and high-yield adverse effects
- What to monitor, common drug interactions, and who is at higher bleeding risk
- Dabigatran reversal with idarucizumab (Praxbind)
- PCI anticoagulation and how DTIs show up in clinical practice (including HIT treatment concepts)

The goal = make medical education easy and clinically relevant.

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Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.