P2Y12 Inhibitors (ADP Inhibitors): Antiplatelet Pharmacology Made Easy
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In this lesson on P2Y12 inhibitors (ADP inhibitors), you’ll learn the high-yield, test-relevant concepts behind the most common antiplatelet drugs used in cardiovascular care. In this lecture from This is Why, Dr. Busti will break down how platelet aggregation inhibitors work, when they’re used clinically, and the key differences between clopidogrel (Plavix), prasugrel (Effient), ticagrelor (Brilinta), and cangrelor (Kengreal)—so you can apply the “why” behind therapy (not just memorize drug names).
You’ll learn how to:
- The P2Y12 (ADP) receptor and how blocking it reduces platelet activation
- Where P2Y12 inhibitors fit in dual antiplatelet therapy (DAPT)
- High-yield uses: acute coronary syndrome (ACS), PCI/stents, and secondary prevention
- Major adverse effects (including bleeding) and top safety pearls
- The exam-favorite comparisons: prodrug activation, onset/offset, reversibility, and IV vs PO options
The goal = make medical education easy and clinically relevant.
Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/p2y12-adp-inhibitors-antiplatelet-pharmacology-review
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#p2y12inhibitors #clopidogrel #antiplateletpharmacology #ticagrelor #drbusti
Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.