Human Genetic Engineering

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

Fifty thousand years ago - merely a blip in evolutionary time - our Homo sapiens ancestors were competing for existence with several other human species, just as their precursors had done for millions of years. Yet something about our species distinguished it from the pack, and ultimately led to its survival while the rest became extinct. Just what was it that allowed Homo sapiens to become masters of the planet? Ian Tattersall, curator emeritus at the American Museum of Natural History, takes us deep into the fossil record to uncover what made humans so special.

V. S. Ramachandran is at the forefront of his field - so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience". Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved.

A giant of archaeology, Colin Renfrew has immeasurably improved our understanding of human history. In this passionately argued work, he offers a concise summary of prehistory - human existence that predates the development of written records - while challenging the very definition of prehistory itself.

Humans live in landscapes of make-believe. We spin fantasies. We devour novels, films, and plays. Even sporting events and criminal trials unfold as narratives. Yet the world of story has long remained an undiscovered and unmapped country. It's easy to say that humans are "wired" for story, but why? In this delightful and original book, Jonathan Gottschall offers the first unified theory of storytelling. He argues that stories help us navigate life's complex social problems.

The study of human evolution is advancing rapidly. Newly discovered fossil evidence is adding ever more pieces to the puzzle of our past, while revolutionary technological advances in the study of ancient DNA are completely reshaping theories of early human populations and migrations. In this Very Short Introduction, Bernard Wood traces the history of paleoanthropology from its beginnings in the 18th century to the very latest fossil finds.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

Book 5: Free the North!: Peace in the south. People settling in. Intelligent creatures moving to Vii from the RV Traveler. Soon, meat will be in short supply. Hungry people will fight for what they need. Braden knows that livestock abounds in the north. It's time to go get some. But free trade in the north has been declared illegal by a new governor.

In this groundbreaking work, evolutionary biologist Jared Diamond stunningly dismantles racially based theories of human history by revealing the environmental factors actually responsible for history's broadest patterns. It is a story that spans 13,000 years of human history, beginning when Stone Age hunter-gatherers constituted the entire human population. Guns, Germs, and Steel is a world history that really is a history of all the world's peoples, a unified narrative of human life.

Why can humans alone invent? In The Pattern Seekers, Cambridge University psychologist Simon Baron-Cohen makes a case that autism is as crucial to our creative and cultural history as the mastery of fire. Indeed, Baron-Cohen argues that autistic people have played a key role in human progress for 70,000 years, from the first tools to the digital revolution. How? Because the same genes that cause autism enable the pattern seeking that is essential to our species' inventiveness.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

In our unique genomes, every one of us carries the story of our species - births, deaths, disease, war, famine, migration, and a lot of sex. But those stories have always been locked away - until now. Who are our ancestors? Where did they come from? Geneticists have suddenly become historians, and the hard evidence in our DNA has completely upended what we thought we knew about ourselves. Acclaimed science writer Adam Rutherford explains exactly how genomics is completely rewriting the human story - from 100,000 years ago to the present.

Evolutionary theory has long established that humans are animals: Modern Homo sapiens are primates who share an ancestor with monkeys and other great apes. Our genome is 98 percent identical to a chimpanzee's. And yet we think of ourselves as exceptional. Are we? In this original and entertaining tour of life on Earth, Adam Rutherford explores the profound paradox of the "human animal".

In A Story of Us, they present this rich narrative and explain how the evolution of our genes relates to the evolution of our cultures. Newson and Richerson take listeners through seven stages of human evolution, beginning seven million years ago with the apes that were the ancestors of humans and today's chimps and bonobos. The story ends in the present day and offers a glimpse into the future.

Approximately 200,000 years ago, as modern humans began to radiate out from their evolutionary birthplace in Africa, Neanderthals were already thriving in Europe - descendants of a much earlier migration of the African genus Homo. But when modern humans eventually made their way to Europe 45,000 years ago, Neanderthals suddenly vanished.

Throughout history, even as daily life has exhibited calm and tolerance, war has never been far away, and even within societies, violence can be a threat. The Goodness Paradox gives a new and powerful argument for how and why this uncanny combination of peacefulness and violence crystallized after our ancestors acquired language in Africa a quarter of a million years ago.

Resistance to malaria. Blue eyes. Lactose tolerance. What do all of these traits have in common? Every one of them has emerged in the last 10,000 years.

Racist pseudoscience is on the rise - fueling hatred, feeding nationalism, and seeping into our discourse on everything from sports to intelligence. Even the well-intentioned repeat stereotypes based on "science", because cutting-edge genetics are hard to grasp - and all too easy to distort. Paradoxically, misconceptions are multiplying amid today's unprecedented surge of research on human genetics. We've never had a clearer picture of who we are and where we come from, and the science, when accurately understood, is a powerful and definitive ally against racism.