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Stephen Breyer, Associate Justice of the United States Supreme Court, gives an insider's perspective on the court as an American institution today and its shaping of our future.

Two Nobel Laureates discuss the genome and more. James D. Watson changed the course of history with his discovery of DNA, the "secret of life". Watson is the recipient of the Presidential Medal of Freedom, the National Medal of Science, and, with Francis Crick and Maurice Wilkins, the 1962 Nobel Prize in Physiology or Medicine.

Is there success after failure? Talk show greats Tavis Smiley and Phil Donohue discuss.

Not long after Hurricane Katrina, Paul Krugman sat down with Thomas Herman, senior special writer for The Wall Street Journal, at the Y on September 29, 2005 to ponder the question, "Whither the Economy?" You can listen to this amazingly insightful talk, in which Krugman discusses the American economy's day of reckoning, his criticism of the Bush administration and former Federal Reserve Chairman Alan Greenspan, the housing bubble, and other warning signs of the current financial crisis.

Mayor Michael Bloomberg is the 108th mayor of the City of New York. Upon taking office in January 2002, his administration was faced with the difficult task of helping the city rebuild and renew itself in the wake of the events of September 11th. Mayor Bloomberg shares his thoughts on the status of the city's recovery, governing through the fiscal crisis, turning the city's economy around, and his struggle to fix the school system.

Four-star General Wesley Clark speaks with Amy Goodman on the effects of war today. Throughout the program, Clark explains some of the characteristics needed for proper leadership of a war. From there, he tells us why, especially in our current political environment, war should be a last resort.

Robert Reich, Bill Clinton's secretary of labor, is concerned that both corporations and consumers have focused so much on profit that they are losing sight of principle. He discusses the importance of moral stands in the world of high finance and investment with The Wall Street Journal's R. Thomas Herman.

Author of the best seller The Red Tent, Anita Diamant, appears in this edition of Live at the 92nd Street Y. Diamant talks about her place in the unfolding story of America's Jewish renaissance, both as a student of Judaism and as a writer/teacher.

As a young man, Earvin "Magic" Johnson admired his father and other small-town entrepreneurs who created jobs and served as leaders in his Midwestern community. He worked for them, watched them, and his interest in building communities through economic development grew even while his basketball career flourished. His fame as an NBA star gave him access to some of the most successful business leaders in the country.

Donny Deutsch is the host of CNBC's talk show The Big Idea with Donny Deutsch. He is the chairman of Deutsch, Inc., the 10th largest marketing company is the United States, as well as an author. Deutsch shares stories of his experiences as an advertising agent as well as his career as a TV personality.

Where do "rights" come from? Professor Alan Dershowitz provides an entirely new resolution to this age-old dilemma: rights, he argues, do not come from God, nature, logic, or law alone, but from particular experiences with injustice, and from trial and error. He also touches on the rights of prisoners and the situation in the Middle East. His new book is Rights from Wrongs. Professor Dershowitz speaks with Jeffrey Toobin, CNN legal analyst and New Yorker staff writer.

Are boys today failing in school because they are lazy, unmotivated, and obsessed with video games? Or are our schools failing to adequately serve male students? Michael Thompson discusses the discrepancy between the performance of female and male students in our schools, and offers possible explanations for the gender gap.

James Carville and Paul Begala, two of the Democratic party's top political strategists, visit with CNN senior analyst Jeff Greenfield in this edition of Live at the 92nd Street Y. Carville and Begala discuss the hottest issues of the day, providing colorful political commentary and insight "from the left".

Scott McClellan, the author of What Happened Inside the Bush White House and What's Going Wrong with Washington (Public Affairs, May, 2008), was White House Press Secretary from 2003-2006, and one of President Bush's closest aides. He speaks with veteran journalist Dan Rather, the managing editor and anchor of Dan Rather Reports on HDNet.

Join Larry Davidson, the producer of the popular North Fork Long Island summer series Writers on the Vine and the host of interview programs on Long Island radio and cable television, for candid stories from Adriana Trigiani and Bill Persky about the business of writing and producing for TV.

At the age of 44, comedian Richard Lewis found himself on a gurney in an emergency room, toxic with alcohol and hallucinating from excess cocaine use. Find out what led him to that point, how he got on the road to recovery and how he stays sober.

Ted Sorensen was John F. Kennedy's special counsel, speechwriter and close adviser. In his intimate and revealing memoir, Counselor: A Life at the Edge of History, Sorensen recalls some of the most dramatic moments of Kennedy's presidency, including the Cuban Missile Crisis, the civil rights movement and the decision to go to the moon. He discusses current events and Kennedy's legacy with noted professor Ralph Buultjens.

Nancy Pelosi was on the path to political prominence when, as a 47-year-old mother of five, she ran for a seat in Congress and won. Now the highest ranking elected woman in American history and the first female Speaker of the House, Pelosi talks candidly about the opportunities and choices that have brought her - and our country - to this time and place. Her latest book is Know Your Power: A Message to America's Daughters.

Join Professor Bernard Lewis at this visit to New York's 92nd Street Y as he shares his thoughts on Iraq and the Middle Eastern power balance.

Former New York Governor Mario Cuomo discusses his hopes and dreams for this country on the eve of a presidential election year. Cuomo was the longest-serving Democratic governor of New York in modern history. He twice set records for the highest popular vote total in a New York State election. Since leaving office, he remains in the public sphere, speaking to audiences about their legacy as Americans and discussing his commitment to social responsibility.