Episode 12 - New Study on Treatments for Non-Alcoholic Fatty Liver Disease in People With HIV With Dr Jordan Lake Recorded Live from CROI 2024

In this episode, Dr Michael Saag speaks with Dr Jordan Lake live from the 2024 Conference on Retroviruses and Opportunistic Infections (CROI). They discuss the prevalence of non-alcoholic fatty liver disease (NAFLD) among people with HIV and explore the effectiveness of the GLP-1 receptor agonist semaglutide, commonly used to treat diabetes and aid in weight loss, to treat NAFLD. Future areas of research are considered, including maintenance strategies post-weight loss and a placebo-controlled version of the study.

00:02 Introduction and Welcome

00:44 Discussion on Non-Alcoholic Fatty Liver Disease in People With HIV

01:56 Role of HIV in Non-Alcoholic Fatty Liver Disease

02:43 Understanding the Inflammation and Fat Accumulation in the Liver

04:38 Exploring the Impact of Nucleoside Therapy on Non-Alcoholic Fatty Liver Disease

06:37 Potential Treatments for Non-Alcoholic Fatty Liver Disease

07:35 The Role of Semaglutide in Treating Non-Alcoholic Fatty Liver Disease

13:36 The Importance of Routine Assessment for Non-Alcoholic Fatty Liver Disease

15:37 Exploring New Drugs for Treating Non-Alcoholic Fatty Liver Disease

18:49 The Challenges and Future Directions in Non-Alcoholic Fatty Liver Disease Research

22:25 Conclusion and Closing Remarks

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Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections.

Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences.

Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.

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