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Dr. Topol’s unprecedented, evidenced-based guide is about how you and your family and friends can benefit from new treatments coming available at a faster rate than ever. From his unique position as a leader overseeing millions in research funding, Dr. Topol also explains the fundamental reasons—from semaglutides to AI—that we can be confident these breakthroughs will continue. Ninety-five percent of Americans over sixty have at least one chronic disease and almost as many have two. That is the essential problem this revolution is solving.

Dr. Andrew Huberman, host of the world’s leading health podcast, Huberman Lab, and neuroscientist and tenured professor at Stanford School of Medicine, introduces Protocols, an essential guide to improving brain function, enhancing mood and energy, optimizing bodily health and physical performance, and rewiring your nervous system to learn new skills and behaviors that can transform your life.

Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit, Armenian and Lithuanian words, all meaning the same thing, and you hear echoes of one of history’s most unlikely journeys. All four languages—along with hundreds of others, from French and Gaelic, to Persian and Polish—trace their origins to an ancient tongue spoken as the last ice age receded. This language, which we call Proto-Indo-European, was born between Europe and Asia and exploded out of its cradle, fragmenting as it spread east and west.

It was Richard Feynman's outrageous and scintillating method of teaching that earned him legendary status among students and professors of physics. From 1961 to 1963, Feynman delivered a series of lectures at the California Institute of Technology that revolutionized the teaching of physics around the world. Six Easy Pieces, taken from these famous Lectures on Physics, represent the most accessible material from the series.

Noraly Schoenmaker was a thirty-something geologist living in the Netherlands when she learned that her live-in partner had been having a long-term affair. Suddenly without a place to stay, she decided to quit her job and jet off to India in search of a new beginning. Her plans were dashed when she fell quickly and helplessly in love: with a motorcycle. Behind the handlebars, she felt alive and free—nimble enough to trace the narrowest paths, powerful enough to travel the longest of roads. In spirit of The Motorcycle Diaries and Wild, this is an inspiring story of self-discovery and renewal.

The centuries-long quest to discover the critical role of germs in disease reveals as much about human reasoning—and the pitfalls of ego—as it does about microbes.

Rachel Barr struggled through years of devastating loss, heartache, and uncertainty until neuroscience gave her the first spark of self-belief she had felt in her adult life — and proof that, because of the brain’s near-infinite potential for neuroplastic change, it’s never too late to carve out neural pathways to form new habits, new skills, and new ways of thinking.

Most of us eat 3 meals a day with a smattering of snacks because we think that’s the normal, healthy way to eat. But when we look at the eating patterns of our distant ancestors, we can see that an intermittent fasting eating pattern is normal—and eating 3 meals a day is not. In The Intermittent Fasting Revolution, prominent neuroscientist Mark Mattson shows that frequent periods of time with little or negligible amounts of food is not only normal but also good for us.

In this gripping work, veteran reporter Christian Davenport chronicles the mad scramble to shape humanity’s off-planet future. He takes readers behind the scenes at NASA and the Pentagon as China’s aggressive moon mining and military plans raise alarms, onto the sprawling Cape Canaveral factory where Bezos works toward Amazon-style lunar deliveries, and onto SpaceX launch pads as Musk’s engineers log 100-hour weeks, ultimately pulling off the harrowing but triumphant launch of its first human spaceflight mission.

When Linda Kohanov wrote The Tao of Equus over twenty years ago, she posed questions that few were asking: Do horses make choices? How do they seem to know what people are thinking and feeling? Are horses spiritual beings? What do they have to teach people? Why are women so attracted to horses? The answers, detailed in this extraordinary chronicle that synthesizes science, behavioral research, and personal insight, transformed how we think about one of humanity's oldest companions and established Kohanov at the vanguard of the emerging field of animal-assisted learning/therapy.

In Love and Math, renowned mathematician Edward Frenkel reveals a side of math we've never seen, suffused with all the beauty and elegance of a work of art. In this heartfelt and passionate book, Frenkel shows that mathematics, far from occupying a specialist niche, goes to the heart of all matter, uniting us across cultures, time, and space.

Until recently, infrastructure was the backbone of organizations' operating software they developed in-house. But now that cloud vendors run the computers, companies can finally bring the benefits of agile custom-centricity to their own developers. Adding product management to infrastructure organizations is now all the rage. But how's that possible when infrastructure is still the operational layer of the company?

It was Richard Feynman's outrageous and scintillating method of teaching that earned him legendary status among students and professors of physics. From 1961 to 1963, Feynman delivered a series of lectures at the California Institute of Technology that revolutionized the teaching of physics. In Six Not-So-Easy Pieces, taken from these famous Lectures on Physics, Feynman delves into one of the most revolutionary discoveries in twentieth-century physics: Einstein's theory of relativity.

Through historical records, revealing interviews, and unflinching statistics, Sarah Goodyear and Doug Gordon, hosts of the podcast The War on Cars, and former host Aaron Naparstek unpack the scale of damage that cars cause, the forces that have created our current crisis and are invested in perpetuating it, and the way that the fight for better transportation is deeply linked to the fight for a more equitable and just society.

Through personal stories, history and cutting-edge science, Ocean uncovers the mystery, the wonder and the frailty of the most unexplored habitat on our planet—and the one which shapes the land we live on, regulates our climate and creates the air we breathe. The book showcase the oceans' remarkable resilience: they are the part of our world that can, and in some cases has, recovered the fastest, if we only give them the chance.

Through a series of beautifully crafted essays, Taylor shares her intimate encounters with the birds that have captured her heart and imagination—from tracking flitting woodpeckers through oak trees to spotting majestic blue jays perched on a Manhattan fire escape; from the exhilaration of witnessing a migratory flock from the top of the Empire State Building to the quiet joy of observing a nest of hatchlings in her own backyard. Through simply paying attention to birds, Lili has been shown a parallel world that is wider and deeper, one of constant change and movement, full of life.

Paleoanthropologist Silvana Condemi and science journalist François Savatier tell the Denisovans’ story in The Secret World of Denisovans. Leading us through the excavation of Denisova cave, the sequencing of the Denisovan genome, and recent research on Denisovan fossils, Condemi and Savatier uncover how the Denisovans migrated to Asia, who they interacted with along the way, and why traces of Denisovan DNA can be found in modern-day humans.

An Olympic athlete. An award-winning novelist. A successful entrepreneur. All raised under one roof. What can we learn from those families whose children aim high and succeed, sometimes in widely varied fields? Just as important: What were the costs along the way, and what can we glean from their travails and triumphs? The acclaimed New York Times journalist Susan Dominus offers compelling profiles of six such families in search of the factors that led to their success—was it an inherited quality, a specific way of parenting, the influence of a sibling, or a twist of luck?

Engaging, thought-provoking, and groundbreaking, The Immortal Mind shows here that some aspect of who we are is spiritual and immortal, transcending the physical body. Using science, he proves the existence of the human soul.

By opening the door to the new field of neuroimmunology,  The Great Nerve not only revolutionizes how we understand and treat disease, it gives us unprecedented hope for our health. This is the story of your body’s ability to heal itself.