• JNP Micro Podcasts: Inhibitory Synaptic Transmission in the Kölliker-Fuse of Rett Syndrome mice

  • Mar 11 2024
  • Length: 10 mins
  • Podcast

JNP Micro Podcasts: Inhibitory Synaptic Transmission in the Kölliker-Fuse of Rett Syndrome mice By cover art

JNP Micro Podcasts: Inhibitory Synaptic Transmission in the Kölliker-Fuse of Rett Syndrome mice

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  • In this episode of JNP's micro podcasts, Jessica R. Whitaker-Fornek of the University of Michigan Medical School discusses the recently published research titled "Inhibitory synaptic transmission is impaired in the Kölliker-Fuse of male, but not female, Rett syndrome mice."

    NEW & NOTEWORTHY Kölliker-Fuse (KF) neurons in acute brain slices from male Rett syndrome (RTT) mice receive reduced inhibitory synaptic inputs compared with wild-type littermates. In female RTT mice, inhibitory transmission was not different in KF neurons compared with controls. The results from this study show that sex-specific alterations in synaptic transmission occur in the KF of RTT mice.

    Inhibitory synaptic transmission is impaired in the Kölliker-Fuse of male, but not female, Rett syndrome mice Jessica R. Whitaker-Fornek, Paul M. Jenkins, and Erica S. Levitt

    Journal of Neurophysiology 2023 130:6, 1578-1587
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