Parts of this book were a turn-off for me...some of the suggestions sounded unobtainable and beyond the reach or regular mortals, especially the parts about diet. Essentially, it seemed that if it tastes good, don't eat it - and I'm not sure that's good advice. No fat, few carbs, even "good ones," no sugars or sugar substitutes, so that leaves nuts, fruits (not too many!) and veggies, especially broccoli. I like the things he suggests eating, but I also like some of the stuff he doesn't.
The non-sedentary lifestyle interested me - I got a pedometer to calculate how much I was walking or active daily....turns out 5000 steps is a lot for me and I feel like I'm moving all the time. But that's sedentary - Australians typically walk 8000 steps without thinking about it.
Sleep I don't really have a problem with - I sleep well and about 8 hrs a night.
I realized about halfway into the book Rath was battling an unusual form of cancer, apparently not immediately life-threatening, but something that must be controlled. That changed my mind about his recommendations as I realized he was fighting for his life and had done much research. For me, that added much validity to his recommendations and told me that we should all be fighting for our lives based on what we eat, how active we are and how we sleep.
I may not be able to or want to follow his regimen completely, but I don't think I can go wrong to follow it as much as possible. With my pedometer as a gauge, I find that I am increasing my activity level, and I do think about what I put in my mouth before I eat it. I suppose that's a good start.