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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.

On a hike during a white-hot summer break on the Greek island of Hydra, Naomi and Samantha make a startling discovery: a man named Faoud, sleeping heavily, exposed to the elements, but still alive. As the two women learn more about the man, a migrant from Syria and a casualty of the crisis raging across the Aegean Sea, their own burgeoning friendship intensifies. But when their seemingly simple plan to help Faoud unravels, all must face the horrific consequences they have set in motion.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Spanning the years of transition, 1944 to 1948, Ascent to Power illuminates Truman’s struggles to emerge as president in his own right. Yet, from a relatively unknown Missouri senator to the most powerful man on Earth, Truman’s legacy transcends. With his come-from-behind campaign in the fall of 1948, his courageous civil rights advocacy, and his role in liberating millions from militarist governments and brutal occupations, Truman’s decisions during these pivotal years changed the course of the world in ways so significant we live with them today.

It's 1918. The war in Europe grinds on, and the Spanish flu seems to be on an insatiable killing spree. But in the small fishing village of Parrsboro, Nova Scotia, a more confined drama-harrowing and provocative-slowly unfolds. It begins when Elizabeth Frame murders her husband hours after their wedding and thrusts the revolver into the blowhole of a beached whale.

An Economist Best Book of the Year A Milwaukee Journal Sentinel Best Book of 2018 ""Enthralling…A clarion call to enlarge American literary history.” — Washington Post “Engrossing, well-researched… This sure-footed history addresses important issues, such as the lack of racial...

Seventeen-year-old Lady Alexandra is strong-willed and sharp-tongued - in a house full of older brothers and their friends, she had to learn to hold her own. Not the best makings for an aristocratic lady in Regency London. Yet her mother still dreams of marrying Alex off to someone safe, respectable, and wealthy. But between ball gown fittings, dances, and dinner parties, Alex, along with her two best friends, Ella and Vivi, manages to get herself into what may be her biggest scrape yet.

In February 1986, the Halland police receive a call from a man who claims to have attacked his first victim. I’m going to do it again, he says before the line cuts off. By the time police officer Sven Jörgensson reaches the crime scene, the woman is taking her last breath. For Sven, this will prove a decisive moment. On the same night, Sweden plunges into a state of shock after the murder of the prime minister. Could there possibly be a connection?

This step by step guide will help you create a practical plan to build wealth through Biotech stock investing. Everybody knows the Wall Street fat cats are making a fortune off the pills in your medicine cabinet. Why not you too?

In April 1942, the Imperial Japanese Army steamrolled through Burma, capturing the only ground route from India to China. Supplies to this critical zone would now have to come from India by air—meaning across the Himalayas, on the most hazardous air route in the world. SKIES OF THUNDER is a story of an epic human endeavor, in which Allied troops faced the monumental challenge of operating from airfields hacked from the jungle, and took on “the Hump,” the fearsome mountain barrier that defined the air route.

No animal is so entangled in human history as the horse. The thread starts in prehistory, with a slight, shy animal, hunted for food. Domesticating the horse allowed early humans to settle the vast Eurasian steppe; later, their horses enabled new forms of warfare, encouraged long-distance trade routes, and ended up acquiring deep cultural and religious significance.

In this enthralling history, internationally bestselling author Max Hastings recounts the odds-defying Operation Biting, a 1942 parachute commando raid on Northern France to steal vital components of German intelligence—one of the most thrilling British commando raids of World War II, and one...