
For Blood and Money
Billionaires, Biotech, and the Quest for a Blockbuster Drug
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Narrado por:
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Rob Shapiro
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De:
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Nathan Vardi
Acerca de esta escucha
A gripping business narrative and scientific thriller about what it takes to bring a wonder drug to market—and save countless lives.
For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
In the multibillion-dollar business of biotech, where pharmaceutical companies, the government, hedge funds, and venture capitalists have spent billions on funding, experimentation, and treatments, a single molecule can stop cancer in its tracks—and make the people who find that rare molecule astonishingly rich. For Blood and Money follows a small team at a biotech start-up in California, who have found one of these rare molecules. Their compound, known as a BTK inhibitor, seems to work on a vicious type of leukemia. When patients start rising from their hospice beds, the team knows they’re onto something big.
What follows is a story of genius, pathos, and drama, in which vivid characters navigate a world of corporate intrigue and ambiguous morality. Vardi’s narrative immerses listeners in the recent explosion of biotech start-ups. He describes the scientists, doctors, and investors who are risking everything to develop new, life-saving treatments, and introduces suffering patients for whom the stakes are life-or-death. A gripping nonfiction listen, For Blood and Money illustrates why it’s so hard to bring new drugs to market, explains why they are so expensive, and examines how profit-driven venture capitalists are shaping the future of medicine.
©2023 Nathan Vardi (P)2023 Audible, Inc.Los oyentes también disfrutaron...
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Historia
It was during the carnival of 1913 that a young Stalin arrived in Vienna on a mission that would launch him into the upper echelon of Russian revolutionaries, and it was here that he first collided with Trotsky. It was in Vienna that the failed artist Adolf Hitler kept daubing watercolors and spouting tirades at fellow drifters in a flophouse. Here, Archduke Franz Ferdinand had a troubled audience with Emperor Franz Joseph - and soon the bullet that killed the archduke would set off the Great War that would kill 10 million more.
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great era great book great narrator
- De John en 03-18-16
De: Frederic Morton
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The Big Ones
- How Natural Disasters Have Shaped Us (and What We Can Do About Them)
- De: Dr. Lucy Jones
- Narrado por: Dr. Lucy Jones
- Duración: 9 h y 20 m
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Earthquakes, floods, tsunamis, hurricanes, volcanoes - they stem from the same forces that give our planet life. Earthquakes give us natural springs; volcanoes produce fertile soil. It is only when these forces exceed our ability to withstand them that they become disasters. Together they have shaped our cities and their architecture; elevated leaders and toppled governments; influenced the way we think, feel, fight, unite, and pray. The history of natural disasters is a history of ourselves.
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Interesting, but neither deep nor insightful
- De Tim en 12-29-18
De: Dr. Lucy Jones
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Material World
- The Six Raw Materials That Shape Modern Civilization
- De: Ed Conway
- Narrado por: Ed Conway
- Duración: 15 h y 11 m
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Sand, salt, iron, copper, oil, and lithium. These fundamental materials have created empires, razed civilizations, and fed our ingenuity and greed for thousands of years. Without them, our modern world would not exist, and the battle to control them will determine our future. In Material World, Ed Conway embarks on an epic journey across continents, cultures, and epochs to reveal the underpinnings of modern life on Earth—traveling from the sweltering depths of the deepest mine in Europe to spotless silicon chip factories in Taiwan to the eerie green pools where lithium originates.
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Insightful
- De Sam en 01-17-24
De: Ed Conway
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The Everything Token
- How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create
- De: Steve Kaczynski, Scott Duke Kominers
- Narrado por: Steve Kaczynski, Scott Duke Kominers
- Duración: 5 h y 22 m
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NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they're a new technology for creating digital assets and providing irrefutable proof of ownership. NFTs open up markets that have never before existed, and are already revolutionizing commerce and brand-building at everything from hot startups to Fortune 500 companies. Kominers and Kaczynski have created a framework that explains what NFTs are, why they’re valuable, and how businesses can leverage them to build highly engaged and intensely loyal communities around their products and brands.
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Great insight
- De Kevin A Perez en 03-30-24
De: Steve Kaczynski, y otros
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Paper Soldiers
- How the Weaponization of the Dollar Changed the World Order
- De: Saleha Mohsin
- Narrado por: Soneela Nankani
- Duración: 9 h y 3 m
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In 1995, Treasury Secretary Robert Rubin re-defined the next thirty years of currency policy that ushered in exceptional prosperity and cheap foreign goods, but the strong dollar policy also played a role in the devastating hollowing out of America’s manufacturing sector. Meanwhile, abroad, the United States increasingly turned to the dollar as a weapon of war. In Paper Soldiers, Saleha Mohsin reveals how the Treasury Department has shaped U.S. policy at home and overseas by wielding the American dollar as a weapon—and what that means in a new age of crisis.
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A must read
- De John K en 10-09-24
De: Saleha Mohsin
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Boom Town
- The Fantastical Saga of Oklahoma City, its Chaotic Founding... its Purloined Basketball Team, and the Dream of Becoming a World-class Metropolis
- De: Sam Anderson
- Narrado por: Sam Anderson
- Duración: 14 h y 55 m
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Oklahoma City was born from chaos. It was founded in a bizarre but momentous "Land Run" in 1889, when thousands of people lined up along the borders of Oklahoma Territory and rushed in at noon to stake their claims. Since then, it has been a city torn between the wild energy that drives its outsize ambitions and the forces of order that seek sustainable progress.
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OKC’s Past & Present Weaved Together
- De dan en 09-09-18
De: Sam Anderson
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The Last Palace
- Europe's Turbulent Century in Five Lives and One Legendary House
- De: Norman Eisen
- Narrado por: Jeff Goldblum
- Duración: 15 h y 36 m
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When Norman Eisen moved into the US ambassador’s residence in Prague, returning to the land his mother had fled after the Holocaust, he was startled to discover swastikas hidden beneath the furniture in his new home. These symbols of Nazi Germany were remnants of the residence’s forgotten history, and evidence that we never live far from the past. From that discovery unspooled the twisting, captivating tale of four of the remarkable people who had called this palace home. Their story is Europe’s....
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Great book despite goldblum’s narration
- De Fernando Ferrante en 01-19-19
De: Norman Eisen
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The Ocean of Churn
- De: Sanjeev Sanyal
- Narrado por: Abhishek Sharma
- Duración: 9 h y 22 m
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In this ambitious audiobook, best-selling author Sanjeev Sanyal chronicles the grand sweep of history from East Africa to Australia, conjuring the great cities of Angkor and Vijayanagar, medieval Arab empires, and Chinese "treasure fleets" in rich, vivid detail. He explores remote archaeological sites, maritime trading networks, and half-forgotten oral tales to challenge established historical narratives with fresh evidence. Shining new light on medieval geopolitics and long-lost cities, The Ocean of Churn is a mesmerizing journey into the heart of a vibrant civilization.
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An unputdownable treatise on the history of Indian Ocean
- De Akash Mitra en 06-20-20
De: Sanjeev Sanyal
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Blaze of Light
- The Inspiring True Story of Green Beret Medic Gary Beikirch, Medal of Honor Recipient
- De: Marcus Brotherton
- Narrado por: Ray Porter
- Duración: 8 h y 25 m
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After dawn the siege began. It was April 1, 1970, and Army Green Beret medic Gary Beikirch knew the odds were stacked against their survival. Some 10,000 enemy soldiers sought to obliterate the 12 American Special Forces troops and 400 indigenous fighters who stood fast to defend 2,300 women and children inside the village of Dak Seang. For his valor and selflessness during the ruthless siege, Beikirch would be awarded a Medal of Honor, the nation's highest and most prestigious military decoration.
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Hope for the future
- De Michael L. Jernigan en 04-09-20
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As Long as Grass Grows
- The Indigenous Fight for Environmental Justice, from Colonization to Standing Rock
- De: Dina Gilio-Whitaker
- Narrado por: Kyla Garcia
- Duración: 7 h y 8 m
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The story of Native peoples’ resistance to environmental injustice and land incursions and a call for environmentalists to learn from the indigenous community’s rich history of activism.
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Unbalanced Information
- De J. Scott en 08-30-22
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The 272
- The Families Who Were Enslaved and Sold to Build the American Catholic Church
- De: Rachel L. Swarns
- Narrado por: Karen Murray
- Duración: 9 h y 32 m
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In 1838, a group of America’s most prominent Catholic priests sold 272 enslaved people to save their largest mission project, what is now Georgetown University. In this groundbreaking account, journalist, author, and professor Rachel L. Swarns follows one family through nearly two centuries of indentured servitude and enslavement to uncover the harrowing origin story of the Catholic Church in the United States. Through the saga of the Mahoney family, Swarns illustrates how the Church relied on slave labor and slave sales to sustain its operations and to help finance its expansion.
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Hard, but absolutely worthwhile.
- De Michael S. Henderson en 09-06-23
De: Rachel L. Swarns
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Imperial Twilight
- The Opium War and the End of China's Last Golden Age
- De: Stephen R. Platt
- Narrado por: Mark Deakins
- Duración: 17 h y 50 m
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As one of the most potent turning points in the country's modern history, the Opium War has since come to stand for everything that today's China seeks to put behind it. In this dramatic, epic story, award-winning historian Stephen Platt sheds new light on the early attempts by Western traders and missionaries to "open" China even as China's imperial rulers were struggling to manage their country's decline and Confucian scholars grappled with how to use foreign trade to China's advantage.
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Balanced readable narrative about the Opium Wars
- De Carl A. Gallozzi en 09-05-18
De: Stephen R. Platt
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Black Earth
- The Holocaust as History and Warning
- De: Timothy Snyder
- Narrado por: Mark Bramhall
- Duración: 16 h y 28 m
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In this epic history of extermination and survival, Timothy Snyder presents a new explanation of the great atrocity of the twentieth century, and reveals the risks that we face in the twenty-first. Based on untapped sources from eastern Europe and forgotten testimonies from Jewish survivors, Black Earth recounts the mass murder of the Jews as an event that is still close to us, more comprehensible than we would like to think and thus all the more terrifying.
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Tough book but worth it!
- De Amazon customer en 11-20-15
De: Timothy Snyder
Lo que los oyentes dicen sobre For Blood and Money
Con calificación alta para:
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- Gregory S Young
- 10-18-23
Entertaining and informative
I really enjoyed the book. Educational about cancer and tech investing. We’ll performed as well.
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- Marina Edler
- 01-20-23
Fascinating look into the ecosystem and politics of drug development
Vardi gives a detailed account of the harrowing story of the grit and perseverance of scientists and investors as they put everything on the line to bring an elegant molecule in a novel class of class of cancer medicines to patients with little alternative. Amazing testament to what people can achieve when they work together. The money involved is mind boggling and not something that I personally focus on, but it is a clear driver for many involved. Highly recommended.
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- Anonymous User
- 04-10-24
a close view of the biotechnology industry
Was riveted by the story of the Ceos and the researchers. I never realized that it is a ruthless field.
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- VL
- 05-23-24
Amazing Ride Through the World of Biotech
Really interesting story with lots of twists and turns as the story unfolds of how two blockbuster drugs were delivered to market.
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- Nishant Gupta
- 07-15-23
Captivating!
Great storyline and narration! The story started slow but really picked up pace over the chapters!
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- ItsBeenReal
- 10-24-23
Great true and timely story of our broken system
Whatever a page turner is for audio...this is it. I am an insider in the industry, and to me this was as good as any action movie.
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- Darcy
- 03-01-23
Really enjoyed this title
A great story at the intersection of cutting edge medical science, high -stakes finance, and human personalities and foibles. I found it fascinating to get an inside view on the development of new drugs, whose failures often exceed their promise, while many others sit on shelves waiting for often serendipitous discovery by financiers and corporations.
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esto le resultó útil a 1 persona
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- J. Muscato
- 02-23-23
Interesting story hampered by incorrect pronunciation
As a hematologist the story of the real world of venture capitalism in the production of this outstanding drug was interesting and disturbing. The docs doing the real work were cast aside because of finance kings- very unfair. The story was hampered by incorrect pronunciation of specific scientific terms (such as the initial mentions of tyrosine kinases and the organization ASH) which would have been easily corrected if the narrator (who is good otherwise) did this in the presence of a person in the field.
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- Patrick Meng-Frecker
- 05-25-24
the sums of money will blow your mind
it was an important story to tell about modern drug development. it's interesting to hear how hedgefunds and investors make massively expensive drug trials possible sometimes taking huge losses but this time making an enormous windfall.
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- Amazon Customer
- 02-16-25
Gripping
So so good!! I work in this field and it really brought alive the stress and tedium of protocols, trials, regulatory reviews…all so boring but a gateway to better health and prosperity.
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