Ep 220 [17 June 2026]: Sandeep Pawar PhD, GM of Life Sciences at Manifold – We discussed Sandeep's unique background and drew on his experience building data and alliances functions at TempusAI and Verana Health to unpack how purpose-built agents are reshaping the biopharma value chain — from translational research through commercial and launch. We covered what makes data agents harder than software agents, what separates a pilot from a scalable solution, and the governance responsibilities that come with this shift. We also explored the ROI should you expect — and where the field is heading. Please refer to his recent blog post for additional background: https://www.linkedin.com/posts/activity-7442251820174929920-8808 Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 219 [10 June 2026]: Wendy Charles PhD, a professor, scientist, and former IRB Director with extensive experience in applying ethical, regulatory, and practical frameworks to real-world healthcare data – We discussed Wendy's unique background and she unpacked the often ambiguous boundary between quality improvement, analytics, and human subjects research—clarifying when real-world data activities require IRB review and how to navigate those decisions with confidence. Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 218 [03 June 2026]: Mal Postings MBA, CEO of Vincigravitas and a RWD industry chief architect – We discussed Mal's unique background and catch-up since his past episodes 32 (12/1/2021) & 90 (3/15/2023). Then we discussed TechnoHealth's 12 Domains: AI-powered care, digital twins, agentic AI, quantum biology, and the move from reactive medicine to proactive health engineering. Shared Material: https://sites.google.com/vincigravitas.org/vincigravitas/technohealth/framework?authuser=0 Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 217 [27 May 2026]: Claire Manneh MPH, Senior Practice Lead for Research Institutions at Datavant – We discussed Claire's unique background and discussed how researchers use real-world data to improve research partnerships, privacy, and patient outcomes. Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 216 [13 May 2026]: Kathleen Mandziuk RN MPH, Athena Innovations founder and research industry veteran – We discussed Kathleen's unique background and explored RWE's evolution—from claims & EHR data to tokenized, AI-driven evidence generation shaping the future of clinical research. References cited during the discussion: > Adjunctions Pro: https://adjunctions.com/pro > PACE Council: https://www.linkedin.com/company/pace-council/ Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 215 [06 May 2026]: Timothy Nobles, Chief Product Officer at Integral – We discussed Timothy's unique background (from musician in a band --> to marketing --> to data science) and discussed how claims and EMR don't speak the same language and explore semantic classification, de-id & compliant linkage to turn messy RWD into life sciences evidence. Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 214 [29 April 2026]: Mika Newton, CEO at xCures Inc. – We referenced Mika's unique background (and he was on RWW for Ep166 on 2025-02-26) and he shared how configurable AI checklists turn messy, unstructured medical records into workflow-ready, validated real-world data. Publication: A Scalable Method for Validated Data Extraction from Electronic Health Records with Large Language Models (https://www.medrxiv.org/content/10.1101/2025.02.25.25322898v2.full) Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.

Ep 213 [22 April 2026]: Wes Michael MBA, President, Rare Patient Voice LLC, now part of Konovo – We discussed Wes' unique background and discussed how rare disease patients want to help science—but they have lives too. Wesley Michael shared how to find, engage, and protect rare patients along with their real-world data. Please check-out our website to join the club, get updates and see podcast recordings: https://rwd-rwe.club Disclaimer: The views expressed in this podcast are the guest's and host's alone, and do not reflect the official position of any organization or entity with whom they are, or have been, professionally affiliated.