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This isn’t medical advice — always talk to your doctor before making any health decisions

In this episode of The Plus SideZ, we break down the latest GLP-1 news and what it actually means in real life.

We’re joined by Dave (Man on Mounjaro), who shares his firsthand experience coming off a GLP-1 after years on treatment, while we also unpack emerging research and what’s coming next in this space.

This conversation covers both data and lived experience, including:

• What new studies say about stopping GLP-1 medications
• Why benefits may reverse after discontinuation
• Real-world weight regain, hunger, and metabolic changes
• Mental health and brain-related effects tied to these medications
• The difference between GLP-1 and GIP and why it matters
• New and emerging medications being studied for neurological and metabolic conditions
• Where treatment may be headed next beyond weight loss

This episode connects the dots between science, patient experience, and the future of obesity treatment so you can better understand what’s happening now and what may be coming next.

Whether you’re on a GLP-1, considering one, or thinking about long-term use, this is a must-listen conversation.

Guest Host: Dave Knapp @OnThePenPodcast

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

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Kim Carlos, Executive Producer

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This isn’t medical advice — always talk to your doctor before making any health decisions.

What happens when one half of a couple goes on a GLP-1, and the other half hops in for the ride?

In this episode, we’re chatting with another couple doing it together, treating their obesity with a GLP-1. You could call them a “GLP-1 household." Libby and Greg, both patients of Ro, talk to us about life going from "Food-Obsessed Couple" to "People Who Actually Have Leftovers."

We’re getting into the nitty-gritty of the "Dual-GLP-1" lifestyle, including:

"Coming Out" Story: How to tell your spouse you’re starting a GLP-1.

The Relationship "Side Effects": Dealing with the "comparison trap," supporting each other through the side effects, and how a boost in confidence changes relationship dynamics.

Household Changes: From challenging the way they talk about "good vs. bad" food to showing up for their kids without the food noise.

This episode is a raw, funny, and medically-backed look at how a simple injection can create a massive ripple effect in a marriage

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

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Kim Carlos, Executive Producer

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Kat Carter, Producer

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Plus SideZ Family,

My (Kim) sister Jessy has passed away just shy of her 39th birthday. I tell you about her in this clip. It’s not scripted and far from perfect sound. Obviously, my family and I are grieving deeply right now. And many people have asked how they can help.

I need to take a little break from the podcast, but we will play some greatest hits & Kat may do an episode or two by herself. During this time, I ask for your continued support to download episodes, leave reviews (desperately need more), comment, share, etc. so our podcast shows up in the algorithm & will be found by people who are lost, sick, and looking for answers & community like you once were.

Thank you for helping my life have bigger meaning & for your support while I’m grieving with my family. I love you.

Send us Fan Mail!

Support the show

Kim Carlos, Executive Producer

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Kat Carter, Producer

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Resources for the Community:

___________________________________________________________________

https://linktr.ee/theplussidez

Find Your US Representatives

https://www.usa.gov/elected-officials ______________________________________________________________________

This isn’t medical advice — always talk to your doctor before making any health decisions.

What happens when one half of a couple goes on a GLP-1, and the other half hops in for the ride?

In this episode, we’re chatting with another couple doing it together, treating their obesity with a GLP-1. You could call them a “GLP-1 household." Libby and Greg, both patients of Ro, talk to us about life going from "Food-Obsessed Couple" to "People Who Actually Have Leftovers."

We’re getting into the nitty-gritty of the "Dual-GLP-1" lifestyle, including:

"Coming Out" Story: How to tell your spouse you’re starting a GLP-1.

The Relationship "Side Effects": Dealing with the "comparison trap," supporting each other through the side effects, and how a boost in confidence changes relationship dynamics.

Household Changes: From challenging the way they talk about "good vs. bad" food to showing up for their kids without the food noise.

This episode is a raw, funny, and medically-backed look at how a simple injection can create a massive ripple effect in a marriage

______________________________________________________________________

Join this channel to get access to perks:

/ @theplussidez

______________________________________________________________________

#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

Send us Fan Mail!

Support the show

Kim Carlos, Executive Producer

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Instagram

Kat Carter, Producer

TikTok

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Resources for the Community:
___________________________________________________________________

https://linktr.ee/theplussidez

Find Your US Representatives
https://www.usa.gov/elected-officials
______________________________________________________________________

This isn’t medical advice — always talk to your doctor before making any health decisions.

GLP-1 News Update:
Kim and Sabina from GLP Winner discuss the latest lawsuits, FDA actions, and state legislation affecting compounded GLP-1 medications.

States currently reviewing restrictions include: Florida, Ohio, Arkansas, Colorado, California, Iowa, Texas, Oregon, Connecticut, and Alabama.

Sources:
frierlevitt.com/state-federal-legislative-developments-drug-compounding-2026
stevenslee.com/glp-1-weight-loss-drug-enforcement

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/ @theplussidez

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

Send us Fan Mail!

Support the show

Kim Carlos, Executive Producer

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Kat Carter, Producer

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Resources for the Community:
___________________________________________________________________

https://linktr.ee/theplussidez

Find Your US Representatives
https://www.usa.gov/elected-officials
______________________________________________________________________

This isn’t medical advice — always talk to your doctor before making any health decisions.

In this episode, we sit down with Hannah, a featured member of Ro’s Healthier with Ro campaign and the focus of Ro’s new documentary on her weight loss and health journey. Hannah joins the show to go beyond a transformation story and dig into the deeper realities of obesity as a chronic disease, GLP-1 treatment, and what lasting change actually feels like.
Hannah shares her experience navigating weight stigma and shame, becoming a runner in a bigger body, and using GLP-1 medication as part of her care. For the first time in her life, she is living in a smaller body, without ever having had a “skinny Hannah” before. She reflects on how that shift has impacted her identity, mental health, and sense of self, including the emotional work that comes with a body changing faster than the mind.
This conversation offers a real-world look at GLP-1 weight loss, body image, and mental health, exploring who we become when our bodies change and how we learn to live in that new reality.

Guest
Hannah
Hannah’s Documentary
https://ro.co/weight-loss/hannah/

Follow Hannah on Instagram
https://www.instagram.com/hf.swede/
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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide
#GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate
#GLP1Community #RealGLP1Stories

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Kim Carlos, Executive Producer

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Resources for the Community:

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Find Your US Representatives

https://www.usa.gov/elected-officials

______________________________________________________________________

This isn’t medical advice — always talk to your doctor before making any health decisions.

Listener note: This episode includes candid discussion about sexual health and intimacy. Private listening is recommended if children are nearby.

For many women in their late 30s, 40s, and 50s, treating metabolic dysfunction with a GLP-1 is only part of the story. Labs may improve. Weight may shift. But sleep changes. Mood feels different. Body composition moves in unfamiliar ways. Libido quietly declines.

Perimenopause and menopause often unfold alongside metabolic treatment, and the hormonal transition can complicate everything.

In this episode, we connect midlife hormone changes with metabolic health. Dr. Cathleen “Dr. Cat” Brown, board-certified OB/GYN and Medical Director at Winona, joins us along with Kelly Miller, Winona Patient Ambassador, to discuss what’s happening during perimenopause and menopause, why hormone replacement therapy is back in the conversation, and what changed after the black box warning.

We also speak candidly about sexual health in midlife, an area that rarely gets the honesty it deserves.

For women navigating GLP-1 treatment or broader obesity care, this conversation widens the lens. Hormones matter. Context matters. And stigma around menopause deserves the same challenge as stigma around obesity.

As always, this episode is for educational purposes only and is not medical advice.

Get started with Winona

https://start.bywinona.com/lp-menopause-care-with-winona?promocode=evergreen20&irclickid=yaKyxywNmxyKR9j1Qg0X3Rj3Uku2WWUNQXbEyw0&irgwc=1&afsrc=1&utm_

Community Guest:

Kelly Miller - Winona Patient Ambassador

Professional Guest:

Dr. Cathleen Brown

fondly known as “Dr. Cat,” is a board-certified OB/GYN with over 12 years of service as an Army physician, where she gained deep experience caring for women’s unique health needs. Today, she works as an OB laborist at Jefferson Abington Hospital near Philadelphia and serves as the Medical Director for Winona.

In her role with Winona, Dr. Cat leads bi-monthly live Q&A sessions with Chief Medical Officer, Dr. Michael Green, answering questions about menopause symptoms and treatment and diving deep into related topics. She also reviews co

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Kim Carlos, Executive Producer

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Kat Carter, Producer

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Resources for the Community:

___________________________________________________________________

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Find Your US Representatives

https://www.usa.gov/elected-officials

______________________________________________________________________

This isn’t medical advice — always talk to your doctor before making any health decisions.

We sit down with Michael Donnelly-Boylen, a leading advocate in the GLP-1 community known as Mike on a Mission, and his husband, a psychiatrist who became certified in obesity medicine. We explore how GLP-1 treatment influenced their relationship, how they grew together, and how advocacy shaped their shared journey, highlighting the ripple effect of health, understanding, and purpose.

Community Guest Mike

Instgram: mike.on.a.mission2

TikTok: mike.onamission2

SubStack: https://mikeonamission2.substack.com/

Professional Guest Kevin Donnelly-Boylen, MD

is a board-certified psychiatrist and obesity medicine physician who combines clinical expertise with lived experience as a patient living with obesity. He is married to Mike Donnelly-Boylen, an obesity care advocate, known on TikTok as Mike on a Mission.

Dr. Donnelly-Boylen earned his medical degree from Georgetown University School of Medicine in 2012. He completed his psychiatry residency at the Massachusetts General Hospital and McLean Hospital program in 2016, followed by a fellowship in Consultation-Liaison Psychiatry at Brigham and Women’s Hospital in 2017.

He has worked in emergency psychiatry and consultation-liaison psychiatry at a safety-net city hospital and currently practices public psychiatry at a state hospital. After witnessing the high rates of co-occurring psychiatric and metabolic illness among his patients, he pursued additional training in obesity medicine and became board-certified in 2025. He now integrates psychiatry and obesity medicine to improve quality of life and long-term health for patients with serious mental illness.

______________________________________________________________________

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

Send us Fan Mail!

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Kim Carlos, Executive Producer

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Kat Carter, Producer

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