What if a simple conversation in the emergency room could reveal who’s most at risk for PTSD before symptoms even begin? Katharina Schultebraucks, PhD, shares her innovative work on using machine learning to forecast mental health outcomes and explains how AI could revolutionize how we detect, prevent, and treat psychiatric disorders. Dr. Schultebraucks is Co-Director of the Computational Psychiatry Program and Associate Professor in the Department of Psychiatry and Population Health at NYU Grossman School of Medicine.

🔍 Topics Covered
00:00 Introduction
00:23 Current Work and Research Focus
01:29 Objective Measures in Psychiatry
02:50 Predicting PTSD Risk
04:28 Early Preventive Interventions
05:47 Machine Learning in Mental Health
09:49 Challenges and Surprises in Research
22:46 Burnout in Emergency Department Providers
27:17 Precision Psychiatry and Future Directions
29:35 Conclusion

📚 Related Resources
-Katharina Schultebraucks, PhD
-Computational Psychiatry Program in NYU Langone’s Department of Psychiatry
-“Dissecting racial bias in an algorithm used to manage the health of populations” by Ziad Obermeyer, et al
-PTSD Treatment at NYU Langone Health

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Executive Producer: Jon Earle

How do you help a child with ADHD stay organized, on task, and confident in school? Richard Gallagher, PhD, a child and adolescent psychologist at NYU Langone Health, shares groundbreaking research on organizational skills training for children with ADHD—a behavioral treatment that’s changing lives and improving classroom performance. This episode dives into how executive functioning challenges manifest in real life, the strengths (and limits) of technology, and the power of parent training and therapeutic coaching to help children thrive.

Dr. Richard Gallagher is Associate Professor in the Department of Child and Adolescent Psychiatry at NYU Grossman School of Medicine, and Director of the Organization Skills Program.

🔍 Topics Covered

00:00 Introduction
00:19 Current Research on Organizational Skills
01:06 Executive Functioning and Practical Interventions
02:37 Impact of Interventions on ADHD
04:41 Expanding Research and Brain Connectivity
05:08 Medication and Organizational Skills
08:11 Technology in ADHD Assessment
15:39 Effective Parenting Styles for ADHD
23:10 Non-Pharmacological Treatments and Future Research
25:58 Conclusion and Final Thoughts

📚 Related Resources

👨‍⚕️More about Dr. Richard Gallagher
🔬 NYU Child Study Center
📘 “Organizational Skills Training for Children with ADHD” by Richard Gallagher, Howard B. Abikoff, and Elana G. Spira
📝 CHADD Parent Training Resources
📈 CDC ADHD Parent Guide

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Executive Producer: Jon Earle

ADHD isn’t just a childhood condition—many adults go undiagnosed for years. Lenard Adler, MD, Director of the Adult ADHD Program at NYU Langone Health, breaks down the nuances of ADHD in adults, the challenges of proper diagnosis, and the latest treatments available. Learn about his research, the screening tools his team has developed, and what’s on the horizon for adult ADHD care.

🔍 Topics Covered:

00:00 Introduction
00:44 Dr. Adler’s Current Research Focus
01:47 Importance of Proper Assessment
03:44 Challenges in Diagnosing Adult ADHD
06:15 Gender Differences in ADHD Diagnosis
07:51 Impact of ADHD on Lifespan
10:10 Comorbidities and Treatment Approaches
14:54 Medication and Treatment Strategies
21:15 Medication Shortages and Solutions
28:42 Recent Developments in ADHD Research
35:01 Screening and Diagnostic Tools
37:33 Conclusion

📚 Related Resources:

• Lenard A. Adler, MD (official bio)
• Adult ADHD Program at NYU Langone Health
• Adult Self-Report Scale (ASRS) Screener
• Life expectancy and years of life lost for adults with diagnosed ADHD in the UK: matched cohort study | The British Journal of Psychiatry
• American Professional Society of ADHD and Related Disorders (APSARD)
• CHADD: ADHD Resources and Support

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Executive Producer: Jon Earle

Despite affecting more Americans than diabetes, substance use is often left out of routine medical care. In this episode, NYU Langone Health’s Jennifer McNeely, MD—a clinician investigator, primary care and addiction medicine physician—explains why that must change. From the surprising history behind addiction’s exclusion from mainstream medicine to the innovative screening tools shaping the future of care, this conversation is a must-listen for anyone interested in addiction care and healthcare policy.

Jennifer McNeely, MD, is an Associate Professor of Medicine and Population Health at NYU Grossman School of Medicine and co-director of the Section on Tobacco, Alcohol, and Drug Use.

🔍 Topics Covered:

00:00 – Introduction
01:15 – Why addiction hasn’t been part of traditional medical care
05:00 – What medications can primary care providers actually prescribe?
07:00 – Why lifting legal barriers isn’t enough
08:00 – Making substance use screening part of routine care
11:50 – The power of self-report screening tools
13:30 – What primary care physicians can actually do after screening
16:10 – Real-world clinical impact of identifying substance use
18:00 – Overcoming stigma and “we don’t do that here” culture
22:17 – Can AI help with screening and care prioritization?

📚 Related Resources:

Jennifer McNeely, MD
Addiction Treatment at NYU Langone
NIDA’s Resources for Clinicians
Substance Use Screening Tools (NIDA)

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Executive Producer: Jon Earle

What makes addiction treatment truly effective? Behavioral scientist Charles Neighbors, MBA, PhD, shares groundbreaking research on the importance of therapeutic relationships, harm reduction, and human connection—love!—in treating substance use disorders. Dr. Neighbors is an Associate Professor in the Departments of Population Health, and Psychiatry at NYU Grossman School of Medicine.

💡 Topics Covered

00:00 Introduction to Dr. Charles Neighbors
01:37 The biggest challenges in addiction treatment
02:24 The Importance of Therapeutic Relationships
05:59 Defining “good treatment” and why love matters
08:05 The role of therapeutic alliance in patient outcomes
14:06 Barriers to change in addiction treatment systems (incl. stigma)
22:04 Harm reduction and safe injection sites: What does the science say?
30:36 Future directions in addiction policy and treatment

📚 Related Resources

• Charles J. Neighbors, MBA, PhD (official bio)
• Dr. Neighbors’ Lab - Health Evaluation & Analytics Lab (HEAL)
• Addiction Treatment at NYU Langone
• Understanding Harm Reduction: National Institute on Drug Abuse (NIDA)
• "Motivational Interviewing" by William R. Miller and Stephen Rollnick
• Community Reinforcement and Family Training (CRAFT)
• SAMHSA’s National Helpline for Mental Health, Drug, Alcohol Issues
• New York State Office of Addiction Services and Supports (OASAS)

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Executive Producer: Jon Earle

For the final episode of Season 2, we're joined by Dr. Samuele Cortese, Professor of Child and Adolescent Psychiatry at the University of Southampton (UK) and Adjunct Full Professor at NYU Langone. Together we explore the intersection of pediatric ADHD and precision psychiatry, including the disorder’s genetic underpinnings and evolving treatment options.

00:00 Introduction
00:54 Dr. Cortese's Research Journey
02:11 Global Perspectives and Challenges in ADHD Treatment
03:51 Advances in ADHD Diagnosis and Treatment
06:41 Role of Genetics in ADHD
09:33 Precision Treatment and Stratification
12:17 Treatment Adherence and Shared Decision-Making
23:55 Connection Between ADHD and Obesity
28:39 Non-Stimulant Alternatives and Future Directions in ADHD Treatment
32:16 Non-Pharmacological Treatments
37:28 Advice for Clinicians and Closing Thoughts

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Executive Producer: Jon Earle

Dr. Timothy Wilens is a Professor of Psychiatry at Harvard Medical School and Chief of the Division of Child and Adolescent Psychiatry at Massachusetts General Hospital. His research interest include the relationship between ADHD, bipolar disorder, and substance use disorders; ADHD pharmacotherapy; and stimulant medication misuse.

On this episode, Dr. Wilens discusses the importance of early diagnosis and intervention in ADHD, as well as its lifelong implications. He takes us through the evolution of ADHD treatment, from behavioral therapies to modern pharmacological interventions, including stimulant and non-stimulant medications, and the application of digital therapeutics. The conversation also touches on the stigma surrounding ADHD, the role of precision medicine, and the future of ADHD research.

00:00 Introduction
02:50 Evolution of ADHD Treatment
04:43 Stigma and Misconceptions
12:18 Importance of Early Intervention
15:02 ADHD Symptoms and Treatment Approaches
30:02 Addressing Concerns About Stimulant Medications
35:50 Navigating the Complexities of ADHD Medication
41:22 Future of ADHD Research and Treatment
43:20 Conclusion

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Executive Producer: Jon Earle

Dr. Ira Glick is Professor Emeritus of Psychiatry and Behavioral Sciences at Stanford University Medical Center, where he has served as director of the Schizophrenia Research Clinic. On this episode, he discusses his research journey, which began in the 1960s and followed a shift from psychoanalysis to biological psychiatry. He addresses the broken social safety net for schizophrenia patients, including the controversial topic of treating some patients against their will, as well as the challenges of medication adherence, and the stigma surrounding severe mental illness.

00:00 Introduction
00:49 Evolution of Schizophrenia Treatment
04:34 Science Behind Schizophrenia Medications
07:39 Addressing the Public Health Challenges of Schizophrenia
11:15 Stigma and Misunderstanding of Severe Mental Illness
21:44 Innovative Treatment Approaches and the Future of Schizophrenia Care
31:36 Importance of Public Health Interventions and Political Will
35:45 Closing Remarks and Future Directions

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Executive Producer: Jon Earle