In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing risks of benzodiazepines and other sedative-hypnotics, overdose risk from overlapping opioid and benzodiazepine prescriptions, non-procedural treatments for peripheral neuropathic pain, NSAIDs as effective alternatives to opioids for postoperative pain, and rising emergency department visits for cannabis hyperemesis syndrome among adolescents.

• Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis Published in BMJ, June 2025
• Association Between Receipt of Overlapping Opioid and Benzodiazepine Prescriptions From Multiple Prescribers and Overdose Risk Published in JAMA Network Open, August 2021
• An overview of the non-procedural treatment options for peripheral neuropathic pain Published in Muscle and Nerve, May 2025
• Randomized Controlled Trial of Nonsteroidal Anti-Inflammatory Drugs as a Safe and Effective Alternative to Opioids for Pain Relief Following Percutaneous Nephrolithotomy Published in the Journal of Endourology, July 2025
• Emergency Department Visits for Cannabis Hyperemesis Syndrome Among Adolescents Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing updated guidance on long-term opioid therapy for nonterminal pain, patterns of high-risk outpatient opioid prescribing, evidence for open-label placebo effects in chronic musculoskeletal pain, links between addictive screen use and youth mental health and suicidality, and more!

• Long-Term Opioid Therapy for Nonterminal Pain Published in American Family Physician, June 2025
• High-risk opioid prescribing trends in the outpatient setting prior to issuance of federal guidance Published Preventative Medicine Reports, September 2019
• A systematic review and meta analysis of open label placebo effects in chronic musculoskeletal pain Published in Scientific Reports, July 2025
• Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths Published in JAMA, July 2025
• Use of Tobacco and Cannabis Following State-Level Cannabis Legalization Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing new evidence on cytisinicline for smoking cessation, links between sedentary behavior and brain health in older adults, factors affecting exercise adherence in chronic low back pain, national trends in postoperative opioid prescribing and persistent use, and, and more!

• Cytisinicline for Smoking Cessation The ORCA Phase 3 Replication Randomized Clinical Trial Published in JAMA Internal Medicine, April 2025
• Sedentary Time Tied to Brain Volume, Worse Cognition in Older Adults Published in MedPage Today, May 2025
• Barriers and enablers to exercise adherence in people with nonspecific chronic low back pain: a systematic review of qualitative evidence Published in Pain, October 24
• Trends in Opioid Prescribing and New Persistent Opioid Use After Surgery in the United States Published in Annals of Surgery, March 2025
• Prevalence of Impairing Substance Use in Injured Drivers Published in JAMA Network Open, April 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing online DBT for chronic pain, national trends in overdose deaths, the effects of exercise on brain activation in osteoarthritis, and more!

• Online Dialectical Behavioral Therapy for Emotion Dysregulation in People With Chronic Pain A Randomized Clinical Trial Published in JAMA Network, May 2025
• US overdose deaths fell 27% last year, the largest one-year decline ever seen Published in AP News, May 2025
• Changes in prefrontal cortex activation with exercise in knee osteoarthritis patients with chronic pain: An fNIRS study Published in the Journal of Clinical Neuroscience, August 2021
• The impact of change in regulations on buprenorphine prescribing for opioid use disorder Published in the American Journal of Health-System Pharmacy, March 2025
• Alcohol Use Disorder Diagnoses Among Individuals Who Take HIV Preexposure Prophylaxis Published in JAMA Network, April 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing oral vs injectable naltrexone, brain function outcomes in long term heavy cannabis use, and more!

• Oral vs Extended-Release Injectable Naltrexone for Hospitalized Patients With Alcohol Use Disorder A Randomized Clinical Trial, Published in JAMA Internal Medicine, April 2025

• Degenerative Disc Disease In Young Adults With Psoriatic Arthritis, Published in the Journal of Rheumatology, February 2025

• Short-term impact of combining pain neuroscience education with exercise for chronic musculoskeletal pain: a systematic review and meta-analysis, Published in Pain, January 2022

• Empowering Pharmacists: Strategies for Addressing the Opioid Crisis through a Public Health Lens, Published in Pharmacy, May 2024

• Brain Function Outcomes of Recent and Lifetime Cannabis Use, Published in JAMA Network Open, January 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the link between dietary fiber intake and osteoarthritis, buprenorphine induction in pharmacies, and more!

• Trajectories of mHealth-Tracked Mental Health and Their Predictors in Female Chronic Pelvic Pain Disorders, Published in the Journal of Pain Research, November 2024

• The association between dietary fiber intake and osteoarthritis: a cross-sectional study from the 1999–2018 U.S. National Health and Nutrition Examination Survey, Published in the Journal of Orthopaedic Surgery and Research, February 2025

• The influence of exercise on pain, disability and quality of life in office workers with chronic neck pain: A systematic review and meta-analysis, Published in Applied Ergonomics, May 2024

• Physician-Delegated Unobserved Induction with Buprenorphine in Pharmacies, Published in the New England Journal of Medicine, January 2023

• Cannabis Use Among Older Adults, Published in JAMA Network Open, May 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing mindfulness vs CBT, the impact of home exercise training for low back pain, and more!

• Mindfulness vs Cognitive Behavioral Therapy for Chronic Low Back Pain Treated With Opioids A Randomized Clinical Trial, Published in JAMA Network Open, April 2025

• Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review, Published in BMJ Open Sport & Exercise Medicine, January 2021

• Effect of Home Exercise Training in Patients with Nonspecific Low-Back Pain: A Systematic Review and Meta-Analysis, Published in the International Journal of Environmental Research and Public Health, August 2021

• Piloting an opioid callback program in community pharmacies, Published in the Journal of the American Pharmacists Association, November-December 2023

• Loss of Medicaid and Treatment of Opioid Use Disorder, Published by JAMA Network Open, May 2025