In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing risks of benzodiazepines and other sedative-hypnotics, overdose risk from overlapping opioid and benzodiazepine prescriptions, non-procedural treatments for peripheral neuropathic pain, NSAIDs as effective alternatives to opioids for postoperative pain, and rising emergency department visits for cannabis hyperemesis syndrome among adolescents.

• Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis Published in BMJ, June 2025
• Association Between Receipt of Overlapping Opioid and Benzodiazepine Prescriptions From Multiple Prescribers and Overdose Risk Published in JAMA Network Open, August 2021
• An overview of the non-procedural treatment options for peripheral neuropathic pain Published in Muscle and Nerve, May 2025
• Randomized Controlled Trial of Nonsteroidal Anti-Inflammatory Drugs as a Safe and Effective Alternative to Opioids for Pain Relief Following Percutaneous Nephrolithotomy Published in the Journal of Endourology, July 2025
• Emergency Department Visits for Cannabis Hyperemesis Syndrome Among Adolescents Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing updated guidance on long-term opioid therapy for nonterminal pain, patterns of high-risk outpatient opioid prescribing, evidence for open-label placebo effects in chronic musculoskeletal pain, links between addictive screen use and youth mental health and suicidality, and more!

• Long-Term Opioid Therapy for Nonterminal Pain Published in American Family Physician, June 2025
• High-risk opioid prescribing trends in the outpatient setting prior to issuance of federal guidance Published Preventative Medicine Reports, September 2019
• A systematic review and meta analysis of open label placebo effects in chronic musculoskeletal pain Published in Scientific Reports, July 2025
• Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths Published in JAMA, July 2025
• Use of Tobacco and Cannabis Following State-Level Cannabis Legalization Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing new evidence on cytisinicline for smoking cessation, links between sedentary behavior and brain health in older adults, factors affecting exercise adherence in chronic low back pain, national trends in postoperative opioid prescribing and persistent use, and, and more!

• Cytisinicline for Smoking Cessation The ORCA Phase 3 Replication Randomized Clinical Trial Published in JAMA Internal Medicine, April 2025
• Sedentary Time Tied to Brain Volume, Worse Cognition in Older Adults Published in MedPage Today, May 2025
• Barriers and enablers to exercise adherence in people with nonspecific chronic low back pain: a systematic review of qualitative evidence Published in Pain, October 24
• Trends in Opioid Prescribing and New Persistent Opioid Use After Surgery in the United States Published in Annals of Surgery, March 2025
• Prevalence of Impairing Substance Use in Injured Drivers Published in JAMA Network Open, April 2025