The COVID-19 pandemic spotlighted burnout in healthcare. While not new, the challenge was compounded by the toll of caring for patients on the frontlines. Burnout rates have swelled since then, and addressing them is not simple.

A recent Johnson & Johnson survey of more than 1,500 surgeons across five countries found that half experience burnout, and 43% have seriously considered leaving surgery.

To understand the implications of the findings, Senior Writer Anastassia Gliadkovskaya speaks with Africa Wallace, M.D., vice president of medical affairs, surgery and medtech at Johnson & Johnson.

She also speaks with Angela Chaudhari, M.D., associate professor and vice chair of faculty affairs at Northwestern University Feinberg School of Medicine. Chaudhari discusses a clinician peer support initiative she directs at Northwestern and the role it plays in mitigating burnout.

To learn more about the topics in this episode:

• Nearly all doctors suffer burnout, survey finds, but many cautiously hopeful that AI could help
• 5 years later: A look back at the COVID-19 pandemic and how healthcare has changed

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In this sponsored episode of Podnosis, CVS Caremark Senior Vice President and Chief Growth Client Success Officer James Margiotta joins host Chris Hayden for an in‑depth look at the rapidly changing pharmacy benefits landscape. Drawing on more than 35 years across payer, PBM, pharmacy and healthcare delivery roles, Margiotta shares what employers and plan sponsors need most in 2026 and beyond: strategic partnership, transparency, affordability and a seamless member experience.

The conversation explores how accelerating drug costs, GLP‑1 utilization, specialty spend and biosimilars are forcing a new, more integrated approach to benefit design. Margiotta highlights how CVS Caremark is leading with technology, AI, clinical rigor and deep connections to the provider ecosystem—helping plan sponsors navigate disruption while improving outcomes and reducing friction for members.

Tune in to learn what meaningful transparency looks like, which cost‑management strategies actually work, and how data and digital innovation are redefining the future of pharmacy benefits.

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Rare diseases, defined in the U.S. as conditions affecting fewer than 200,000 people, can take years, if not decades, to diagnose. About 10,000 rare diseases affect 30 million Americans, and half of those patients are children.

What if rare diseases could be identified early and treated proactively before they progress? That is becoming more possible thanks to advances in genetic testing. One company, GeneDx, is on a mission to address diagnostic challenges through faster, more affordable genome testing.

To explain the evolution of this technology, how it is changing lives and where it may go in the future, Senior Writer Anastassia Gliadkovskaya speaks with GeneDx CEO Katherine Stueland.

To learn more about the topics in this episode:

• RNA sequencing spots 40% more cancer mutations in children than standard genetic tests: study
• Regeneron, Illumina and more back Truveta for 10M genome sequencing project
• Survey: Many rare disease patients struggle to navigate care

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Emergency departments are required by law to treat anyone who comes through the door. But the financial model behind that guarantee is under strain.

In this episode of "Podnosis," Fierce Healthcare and Life Sciences Editor-in-Chief Ayla Ellison talks with Tony Cirillo, M.D., president of the American College of Emergency Physicians, about the business of emergency medicine—who pays, how much, and what happens when the math stops working.

To learn more about the topics in this episode:

• Without new financial support, emergency departments, physicians struggle to meet rising demand: RAND
• Op-ed: What if the ER is the emergency?
• Op-ed: Emergency physicians are holding the line, but we can't do it alone

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Fierce Healthcare's Fierce 15 is one of our favorite projects each year. Now in its eighth year, the list highlights companies bringing new ideas and innovation to some of healthcare’s most persistent challenges.

In this episode, members of the Fierce Healthcare editorial team discuss the Fierce 15 of 2026 and the trends shaping this year’s honorees—from AI-powered clinical tools to companies tackling insurance denials, behavioral health integration and early cancer detection.

The conversation also looks at what these companies reveal about the direction of healthcare, including the growing role of AI, the push for accountability across the system and the different paths startups are taking to build sustainable businesses.

To learn more about the topics in this episode:

• Fierce Healthcare's Fierce 15 of 2026
• Fierce Healthcare highlights Fierce 15 of 2026 honorees at NYSE

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Healthcare earnings season is offering a mixed picture of the industry.

In the latest episode of "Podnosis," Fierce Healthcare's Dave Muoio and Paige Minemyer break down the highlights from fourth-quarter earnings, where providers signaled growth while payers warned of financial headwinds amid a shifting policy landscape.

The episode also features an interview from the Lake Nona Impact Forum, where Fierce Healthcare’s Anastassia Gliadkovskaya spoke with Jeff DiLullo, head of Philips North America, about how health systems are thinking about AI, technology and the push to bring care closer to home.

To learn more about the topics in this episode:

• UnitedHealth Group was the most profitable payer in a difficult 2025 for the industry
• After 2025's volumes shortfall, Universal Health Services says capacity, headcount investments will pay off in 2026
• Community Health Systems' hospital divestiture streak likely isn't over
• Tenet Health outperforms in Q4, projects solid 2026 despite ACA exchange headwinds
• HCA Healthcare unveils bullish 2026 guidance despite $600M-$900M ACA exchanges hit
• Lake Nona Impact Forum: There can't be longevity without tech
• Philips to invest $150M in US manufacturing base, including ultrasound site expansion
• Philips rolls out major AI upgrades for cardiac ultrasound platforms
• Philips launches new point-of-care ultrasound system for critical care

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Measurement-based care is increasingly referenced in conversations across the behavioral health industry. Providers recognize the value of patient-reported outcomes as a way to track progress.

Yet there are important considerations in doing measurement-based care well.

To understand what those are, Senior Writer Anastassia Gliadkovskaya speaks with Two Chairs’ Chief Clinical Officer Colleen Marshall about the company’s approach to clinician training, its internal culture of measurement and the outcomes it has seen.

To learn more about the topics in this episode:

• Employers can do more to track the efficacy of mental health benefits, study says

• How tech, incentives could push measurement-based care in behavioral health
• A closer look at the impact of measurement-based care in behavioral health

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In five to 10 years, a hospital room could look very different. Advocate Health is beginning to build that room of the future today. The concept integrates advanced artificial intelligence capabilities, virtual nursing and audio, video and sensor data for intelligent patient monitoring, creating an extra set of eyes and ears for care teams. Nurses and clinicians can respond more quickly and proactively, while patients receive real-time assistance. Virtual technology also allows family members to participate in care from outside the room.

Advocate Health is piloting the room of the future at two hospitals in Charlotte, North Carolina, and Fierce Healthcare got a firsthand look at the initiative. On site, Executive Editor Heather Landi spoke with Molly McColl, Advocate Health’s vice president of virtual health and clinical transformation, about how the tech-enabled hospital room supports care teams, improves the patient experience and expands access to care, particularly in rural communities.

To learn more about the topics in this episode:

• A conversation with Eugene Woods, the architect of 'Applied Hope'

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