Mostrando resultados por autor "Vertex Pharmaceuticals" en Todas las categorías

Daphne always loved the way her fiancé Peter told their story. How they met (on a blustery day), fell in love (over an errant hat), and moved back to his lakeside hometown to begin their life together. He really was good at telling it…right up until the moment he realized he was actually in love with his childhood best friend Petra.

Coexisting but conflicting needs create self-sabotaging behaviors. This is why we resist efforts to change, often until they feel completely futile. But by extracting crucial insight from our most damaging habits, building emotional intelligence by better understanding our brains and bodies, releasing past experiences at a cellular level, and learning to act as our highest potential future selves, we can step out of our own way and into our potential.

Women can be heroes. When twenty-year-old nursing student Frances “Frankie” McGrath hears these words, it is a revelation. Raised in the sun-drenched, idyllic world of Southern California and sheltered by her conservative parents, she has always prided herself on doing the right thing. But in 1965, the world is changing, and she suddenly dares to imagine a different future for herself. When her brother ships out to serve in Vietnam, she joins the Army Nurse Corps and follows his path.

When 19-year-old huntress Feyre kills a wolf in the woods, a beast-like creature arrives to demand retribution for it. Dragged to a treacherous magical land she only knows about from legends, Feyre discovers that her captor is not an animal, but Tamlin - one of the lethal, immortal faeries who once ruled their world.

The identity comes first: Evie Porter. Once she’s given a name and location by her mysterious boss Mr. Smith, she learns everything there is to know about the town and the people in it. Then the mark: Ryan Sumner. The last piece of the puzzle is the job. Evie isn’t privy to Mr. Smith’s real identity, but she knows this job will be different. Ryan has gotten under her skin, and she’s starting to envision a different sort of life for herself. But Evie can’t make any mistakes—especially after what happened last time.

No matter your goals, Atomic Habits offers a proven framework for improving - every day. James Clear, one of the world's leading experts on habit formation, reveals practical strategies that will teach you exactly how to form good habits, break bad ones, and master the tiny behaviors that lead to remarkable results. If you're having trouble changing your habits, the problem isn't you. The problem is your system. Bad habits repeat themselves again and again not because you don't want to change, but because you have the wrong system for change.

Everyone knows that Colin Bridgerton is the most charming man in London. Penelope Featherington has secretly adored her best friend's brother for...well, it feels like forever. After half a lifetime of watching Colin Bridgerton from afar, she thinks she knows everything about him, until she stumbles across his deepest secret...and fears she doesn't know him at all.

Harry Potter has never even heard of Hogwarts when the letters start dropping on the doormat at number four, Privet Drive. Addressed in green ink on yellowish parchment with a purple seal, they are swiftly confiscated by his grisly aunt and uncle. Then, on Harry's eleventh birthday, a great beetle-eyed giant of a man called Rubeus Hagrid bursts in with some astonishing news: Harry Potter is a wizard, and he has a place at Hogwarts School of Witchcraft and Wizardry. An incredible adventure is about to begin!

Twenty-year-old Violet Sorrengail was supposed to enter the Scribe Quadrant, living a quiet life among books and history. Now, the commanding general—also known as her tough-as-talons mother—has ordered Violet to join the hundreds of candidates striving to become the elite of Navarre: dragon riders. But when you’re smaller than everyone else and your body is brittle, death is only a heartbeat away...because dragons don’t bond to “fragile” humans. They incinerate them.

Amoral, cunning, ruthless, and instructive, this piercing work distills 3,000 years of the history of power into 48 well-explicated laws. This bold volume outlines the laws of power in their unvarnished essence, synthesizing the philosophies of Machiavelli, Sun Tzu, Carl von Clausewitz, and other infamous strategists. The 48 Laws of Power will fascinate any listener interested in gaining, observing, or defending against ultimate control.

Here is the novel that will be forever considered a triumph of the imagination. Set on the desert planet Arrakis, Dune is the story of the boy Paul Atreides, who would become the mysterious man known as Maud'dib. He would avenge the traitorous plot against his noble family and would bring to fruition humankind's most ancient and unattainable dream.

Lily hasn’t always had it easy, but that’s never stopped her from working hard for the life she wants. She’s come a long way from the small town where she grew up—she graduated from college, moved to Boston, and started her own business. And when she feels a spark with a gorgeous neurosurgeon named Ryle Kincaid, everything in Lily’s life seems too good to be true.

In the dark, filthy salt mines of Endovier, an 18-year-old girl is serving a life sentence. She is a trained assassin, the best of her kind, but she made a fatal mistake. She got caught. Young Captain Westfall offers her a deal: her freedom in return for one huge sacrifice. Celaena must represent the prince in a to-the-death tournament - fighting the most gifted thieves and assassins in the land. Live or die, Celaena will be free. Win or lose, she is about to discover her true destiny. But will her assassin's heart be melted?

Justin has a curse, and thanks to a Reddit thread, it's now all over the internet. Every woman he dates goes on to find their soul mate the second they break up. When a woman slides into his DMs with the same problem, they come up with a plan: They'll date each other and break up. Their curses will cancel each other’s out, and they’ll both go on to find the love of their lives. It’s a bonkers idea… and it just might work.

There is no bigger public health story now than the collapse in youth mental health. The numbers are terrifying and dominate our headlines. There has been much debate over how we got here, and what to do next, and bestselling author and social psychologist Jonathan Haidt is at the white-hot center of that discourse. Haidt has spent his career speaking wisdom and truth into the most difficult landscapes—communities polarized by politics and religion, campuses battling culture wars, and now the perfect storm contributing to a public health emergency for Gen Z.

Romance can be a little complicated when you get sucked into a wormhole. Just ask high school English teacher June Flint. One little solar flare happens and suddenly you find yourself 85 years in the future. Eighty-five years from your dream job. Your ailing mother whose only companion in this world is you. Your favorite stuffed-crust pizza from DeLucia’s on Sunday nights. But when June’s cell phone inexplicably picks up a signal, she’s able to call back to the present—more specifically, four weeks before she accidentally time traveled.

Alex Volkov is a devil blessed with the face of an angel and cursed with a past he can't escape. Driven by a tragedy that has haunted him for most of his life, his ruthless pursuits for success and vengeance leave little room for matters of the heart. But when he's forced to look after his best friend's sister, he starts to feel something in his chest. Ava Chen is a free spirit trapped by nightmares of a childhood she can't remember. But despite her past, she's never stopped seeing the beauty in the world . . . including the heart beneath the icy exterior of a man she shouldn't want.

For decades we've been told that positive thinking is the key to a happy, rich life. "F*ck positivity," Mark Manson says. "Let's be honest, shit is f*cked, and we have to live with it." In his wildly popular Internet blog, Manson doesn't sugarcoat or equivocate. He tells it like it is - a dose of raw, refreshing, honest truth that is sorely lacking today. The Subtle Art of Not Giving a F*ck is his antidote to the coddling, let's-all-feel-good mind-set that has infected modern society and spoiled a generation, rewarding them with gold medals just for showing up.

It’s 1984, and life has changed beyond recognition. Airstrip One, formerly known as Great Britain, is a place where Big Brother is always watching, and nobody can hide. Except, perhaps, for Winston Smith. Whilst working at the Ministry of Truth, rewriting history, he secretly dreams of freedom. And in a world where love and sex are forbidden, where it’s hard to distinguish between friend and foe, he meets Julia and O’Brien and vows to rebel.

Darrow is a Red, a member of the lowest caste in the color-coded society of the future. Like his fellow Reds, he works all day, believing that he and his people are making the surface of Mars livable for future generations. Yet he spends his life willingly, knowing that his blood and sweat will one day result in a better world for his children. But Darrow and his kind have been betrayed. Soon he discovers that humanity reached the surface generations ago. Vast cities and sprawling parks spread across the planet.

After Tova Sullivan’s husband died, she began working the night shift at the Sowell Bay Aquarium, mopping floors and tidying up. Keeping busy has always helped her cope, which she’s been doing since her eighteen-year-old son, Erik, mysteriously vanished on a boat in Puget Sound over thirty years ago. Tova becomes acquainted with curmudgeonly Marcellus, a giant Pacific octopus living at the aquarium. Marcellus knows more than anyone can imagine but wouldn’t dream of lifting one of his eight arms for his human captors—until he forms a remarkable friendship with Tova.