For more exclusive content on metabolic health, including additional videos with Dr. Andrew Koutnik, check out our membership platform for free here!

Despite incredible advances in diabetes technology, blood sugar control in people with Type 1 diabetes hasn’t meaningfully improved in over a decade. In this eye-opening episode recorded live at Metabolic Health Summit, Dr. Andrew Koutnik - a scientist, patient, and advocate - dives into the science behind this paradox.

Dr. Koutnik shares groundbreaking data from the largest-ever analysis of carbohydrate intake in people with Type 1 diabetes, explores the limitations of current technology, and presents a rare 10-year case study examining the long-term safety and efficacy of carbohydrate restriction.

From CGMs to closed-loop systems, from meal composition to insulin dosing, this episode challenges conventional assumptions and offers a compelling case for nutrition as a powerful - yet underutilized - tool in diabetes care.

Special thanks to the sponsors of this episode:

• Genova Connect – Get 15% off any test kit with code METABOLICLINK here
• SelectQuote - Save more than 50% on term life insurance here
• iRestore - Get a huge discount on the iRestore Illumina Face Mask with code METABOLICLINK here

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

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Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

For more exclusive content on metabolic health and therapy, check out our membership platform for free: https://membership.metabolicinitiative.com

In this Journal Club edition of The Metabolic Link, hosts - Victoria Field, Dr. Dominic D’Agostino, and Dr. Angela Poff dissect two powerful papers reshaping our understanding of metabolic health. First up: a striking human study showing that exposure to sugar rationing during the first 1,000 days of life reduced the risk of type 2 diabetes and hypertension decades later—offering a rare glimpse into how early-life nutrition programs lifelong health. Then, the team dives into a landmark publication proposing a clinical research framework for ketogenic metabolic therapy in glioblastoma. With insights on developmental programming, public policy, and personalized metabolic approaches to cancer, this is a must-listen for anyone passionate about where science meets societal change.

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ ZocDoc - Find and instantly book a top-rated doctor here
✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here

Read both papers here:

1. Exposure to sugar rationing in the first 1000 days of life protected against chronic disease
2. Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

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Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

What’s really causing America’s obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model.

Moderated by host Dr. Dominic D’Agostino, the discussion dives deep into the biological roots of obesity, the relevance of sugar-sweetened beverages, the role of leptin and uric acid, and whether it’s fructose or calories that are driving the crisis. Despite their differing perspectives, both experts agree on one critical point—our modern food environment is fueling metabolic dysfunction on a massive scale.

This is one of the most nuanced and constructive conversations you’ll hear on the topic of obesity science.

References submitted by both guests can be found here!

For more exclusive interviews and presentations with Dr. Johnson and Dr. Norton along with 100s of other videos on metabolic health and therapy, ad-free private episodes of The Metabolic Link, and to earn CMEs visit our member medical education platform: https://membership.metabolicinitiative.com

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ iRestore – Get a huge discount when you use the code METABOLICLINK here
✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here

Learn more about Dr. Layne Norton
Learn more about Dr. Richard Johnson

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

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Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Join us for a Live Q&A on June 18th at 9am PT/12pm ET with Dr. Anthony Chaffee and also enjoy ad-free exclusive episodes, videos covering the latest science on metabolic health on therapy, and earn CMEs by clicking here.

In this episode, Dr. Anthony Chaffee—medical doctor, neurosurgical registrar, and nutrition educator—joins Dr. Dominic D’Agostino for a thoughtful exploration of the scientific rationale behind animal-based ketogenic diets.

Together, they discuss burgeoning interest in how this approach could support metabolic health, reduce inflammation, and potentially improve outcomes in chronic conditions. Dr. Chaffee also shares his personal journey, evolutionary insights, and emerging clinical cases that invite a reexamination of modern dietary assumptions.

Whether you’re a practitioner, patient, or simply curious about low-carb, ketogenic, or elimination-based nutrition strategies, this conversation offers valuable perspective on food, metabolism, and human health.

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ Fatty15 – Get 15% off a 90-day Starter Kit with the code METABOLICLINK here
✅ Zocdoc – Find and instantly book a top-rated doctor here

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
• Facebook
• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health and therapy, and earn CMEs here!

In this deeply personal and courageous episode of The Metabolic Link, we hear from patient advocate and podcast co-host Matt Baszucki, who shares how he endured—and ultimately overcame—type 1 bipolar disorder through a radical shift in treatment: ketogenic metabolic therapy.

After years of hospitalizations, debilitating mood episodes, and failed conventional treatments, Matt found hope through the emerging field of metabolic psychiatry. With the help of his family, including support and clinical guidance from Dr. Christopher Palmer, Matt adopted a therapeutic ketogenic diet in 2021—and the results were extraordinary.

Now a thriving project manager in Silicon Valley and co-host of The BipolarCast, Matt is helping drive a movement that challenges the very foundation of how we treat mental illness. This episode is not just about recovery—it's about transformation, resilience, and the future of mental health care.

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ iRestore – Get a huge discount when you use the code METABOLICLINK here

Watch Matt Baszucki's YouTube Channel here and Bipolar Cast here. Learn more about the non-profit, Metabolic Mind, here.

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
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• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here!

If you’re a clinician, scientist, or anyone interested in taking a deep dive into the complexities of hormone regulation, this episode of The Metabolic Link Podcast is for you! Recorded live at Metabolic Health Summit 2024, this in-depth presentation by Dr. Kyle Gillett—dual board-certified in family and obesity medicine—dives deep into the biochemical, clinical, and therapeutic layers of hormone health.

From his foundational “Seven Pillars of Health” to cutting-edge insights on peptides, receptor affinity, and hormone testing strategies, Dr. Gillett provides a masterclass on optimizing hormones for performance, longevity, and metabolic resilience. Designed for professionals and educated listeners alike, this talk bridges clinical relevance with scientific nuance.

Access even more from Dr. Gillett—like his exclusive Hormones 101 lecture—inside our medical education platform, The Metabolic Initiative. Start your free trial at https://membership.metabolicinitiative.com.

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ Fatty15 – Get 15% off a 90-day Starter Kit with the code METABOLICLINK here
✅ Zocdoc – Find and instantly book a top-rated doctor here
✅ Puori – Get 20% off supplements with code METABOLICLINK here

Learn more about Dr. Gillett here!

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
• Facebook
• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com

In today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacting adults, but alarmingly, children and adolescents too.

You'll learn about the latest updates in terminology, such as Metabolic Dysfunction Associated Steatohepatitis (MASH) and Metabolic Dysfunction Associated Steatotic Fatty Liver Disease (MASLD), highlighting a critical connection to underlying metabolic dysfunction. Plus, discover exciting dietary strategies—like therapeutic carbohydrate restriction—that hold potential not just to prevent, but to actually reverse liver fat accumulation.

If you've ever wondered how your diet and lifestyle choices directly shape your metabolic health, this episode delivers practical insights and actionable information straight from cutting-edge science. Don't miss this deep dive into the latest science on NAFLD—and how simple shifts today could dramatically improve your metabolic health tomorrow.

Special thanks to the sponsors of this episode:

• Genova Connect – Get 15% off any test kit with code METABOLICLINK here
• Maui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products here
• iRestore: Use code METABOLICLINK for exclusive discounts on the iRestore Illumina Face Mask here
• Puori – Get 20% off supplements with code METABOLICLINK here

Read the papers discussed here:

• https://pubmed.ncbi.nlm.nih.gov/38521116/
• https://pubmed.ncbi.nlm.nih.gov/38914224/
• https://pubmed.ncbi.nlm.nih.gov/38771552/
• https://pubmed.ncbi.nlm.nih.gov/38723301/
  
  

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

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• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here!

In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Spencer Nadolsky—board-certified obesity and lipid specialist, former NCAA heavyweight wrestler, and founder of Vineyard—to explore one of the most hotly debated and often misunderstood tools in modern medicine: GLP-1 receptor agonists.

Together, they take a deep dive into how these drugs work, who they’re for, and why they might not always be a magic bullet. Dr. Nadolsky shares clinical insights into the real-world use of semaglutide, tirzepatide, and combination therapies, breaking down everything from appetite regulation and side effects to muscle loss, mood changes, and the potential future of prevention.

They also tackle pediatric obesity, long-term use vs. off-ramping, and the critical role of resistance training and nutrition for protecting muscle mass while on these medications.

Special thanks to the sponsors of this episode:

✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ Fatty15 – Get 15% off a 90-day Starter Kit here (use code METABOLICLINK)
✅ Zocdoc – Find and instantly book a top-rated doctor here
✅ Puori – Get 20% off supplements with code METABOLICLINK here

🧠 Learn more about Dr. Nadolsky → drspencer.com

💥 Don’t forget to RSVP for the live Q&A on April 22!
🎟️ membership.metabolicinitiative.com/drspencer

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
• Facebook
• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.