Episodios

  • #494 C. diff, Diarrhea, the Microbiome, and New Therapies with Dr. Cynthia Sears. Live from Johns Hopkins Grand Rounds

    #494 C. diff, Diarrhea, the Microbiome, and New Therapies with Dr. Cynthia Sears. Live from Johns Hopkins Grand Rounds
    Aug 11 2025
    Dominate C. diff! Learn to distinguish colonization from infection, select first-line therapies, and counsel patients on recurrence prevention and microbiome recovery. We’re joined by IDSA past president and expert on foodborne and intestinal infections, Dr. Cindy Sears (Johns Hopkins University) for a comprehensive update on Clostridioides difficile (C. diff, Cdiff, CDAD, CDI).

    Claim CME for this episode at curbsiders.vcuhealth.org!

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    Show Segments

    • 00:00 Intro
    • 03:00 Guest bio and hobby
    • 04:25 Case of Charles Fleur Fontaine
    • 06:00 Risk factors and epidemiology
    • 08:00 Antibiotic hierarchy of risk
    • 10:00 Diagnosis, testing strategies
    • 14:00 Defining severity
    • 17:30 Treatment options
    • 20:00 Microbiome recovery strategies
    • 24:00 Probiotics and postbiotics
    • 27:00 Infection control counseling
    • 30:00 C. diff and colon cancer
    • 32:00 Recurrent C. diff strategies
    • 35:00 Why some FMT and bezlotoxumab were discontinued
    • 38:00 Microbiota replacement therapies
    • 43:00 Prophylaxis strategies
    • 45:00 Future therapies and ongoing research
    • 47:00 Audience Q&A
    • 52:00 Outro

    Credits

    • Written and Produced by: Matthew Watto, MD, FACP
    • Cover Art and Infographic by:
    • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Reviewer: Sai S Achi MD,MBA,FACP
    • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Technical Production: PodPaste
    • Guest: Cynthia Sears MD

    Disclosures

    Dr. Sears reports no relevant financial disclosures. Dr. Williams financial relationships disclosed include a Merck grant or research support. This relationship has not ended.

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    58 m
  • Bonus: Hypermobility Q&A with Bendy Bodies Dr. Linda Bluestein

    Bonus: Hypermobility Q&A with Bendy Bodies Dr. Linda Bluestein
    Aug 7 2025
    In this special bonus episode, Dr. Linda Blustein (Bendy Bodies https://bit.ly/m/BendyBodies) addresses listener questions about Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorders.

    00:00 – Introduction
    00:59 – Can PCPs diagnose hEDS without a geneticist?
    03:19 – Limitations of the Beighton Score
    05:40 – 2017 hEDS criteria & upcoming revisions
    10:29 – How to find a knowledgeable provider
    12:52 – SVT vs POTS in a patient with EDS family history
    19:53 – How to ask your provider if they’re comfortable treating dysautonomia
    22:17 – MTHFR variants and hEDS
    29:23 – Celiac, gluten sensitivity & EDS
    31:48 – Food allergy vs sensitivity testing
    34:11 – Lipoedema and hypermobility
    39:00 – LDN, Ketotifen, and Cromolyn
    43:41 – Medication sensitivity in EDS/POTS/MCAS patients
    45:47 – Wrap up and resources

    ​FIGS
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    Locumstory
    ​Locumstory.com is simply a free, unbiased educational resource about locum tenens

    Grammarly
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    51 m
  • REBOOT: #452 NAFLD/MASLD with Dr. Elliot Tapper

    REBOOT: #452 NAFLD/MASLD with Dr. Elliot Tapper
    Aug 4 2025
    We have a classic Curbsiders episode for you. Expert guest Dr. Elliot Tapper (@ebtapper) shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.


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    1 h y 14 m
  • #493: Joint Pain in Older Adults with Dr. Una Makris

    #493: Joint Pain in Older Adults with Dr. Una Makris
    Jul 28 2025
    An age-friendly approach to arthralgias.

    Attack arthralgias with ease! Learn how to evaluate and manage common joint complaints in older adults. We’re joined by Dr Una Makris, @unamakris.bsky.social (UT Southwestern).

    Claim CME for this episode at curbsiders.vcuhealth.org!

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    Show Segments

    • Intro
    • Case 1 from Kashlak
    • General approach to joint pain in older adults
    • Diagnosing osteoarthritis
    • Management of osteoarthritis in older adults
      • Non-pharmacological interventions
      • Pharmacological interventions: topicals, orals, injectables
      • When to refer for joint replacement
    • Case 2 from Kashlak
    • Diagnosis of Late onset rheumatoid arthritis (LORA)
      • Differential Diagnosis and Distinguishing features
      • Lab work/Imaging
      • When to refer to rheumatology
    • Approach to managing LORA
      • The 5Ms framework
      • Initial treatment with glucocorticoids
      • Ageism as a driver of undertreatment in older adults
      • Treating to target
    • Key takeaways
    • Outro

    Credits

    • Producers, Writers and Show Notes: Joseph (Lee) Young, MD, Leah Witt, MD, Rachel Miller, MD
    • Cover Art and Infographic: Leah Witt, MD
    • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Reviewer: Emi Okamoto, MD
    • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Technical Production: PodPaste
    • Guest: Dr. Una Makris

    Disclosures

    Dr. Makris reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.


    Sponsor: Heart of Care

    If you care about patient safety, team performance, and building a culture of readiness, subscribe to In the Heart of Care. Available now, wherever you get your podcasts.

    Sponsor:     FIGS

    Curbsiders listeners can get 15% off. Just go to wearFIGS.com and use code FIGSRX.

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    1 h y 14 m
  • REBOOT: #454 Kidney Boy on Managing Diabetes and Hypertension in CKD

    REBOOT: #454 Kidney Boy on Managing Diabetes and Hypertension in CKD
    Jul 24 2025
    Here is a classic Curbsiders episode with one of our favourite guests of all time, Dr Joel Topf.

    Learn how to manage diabetes and hypertension in chronic kidney disease with expert tips from Kidney Boy, Kashlak’s Chief of Nephrology, Dr. Joef Topf @kidney_boy.

    Finerenone is FDA approved for managing CKD in patients with diabetes. **Update as of July 2025: The non-steroidal mineralocorticoid recepter antagonist, finerenone is now FDA approved to treat heart failure with LVEF at or above 40% based on results of the FINEARTS-HF trial. **

    Claim CME for this episode at curbsiders.vcuhealth.org!

    Heart of Care
    If you care about patient safety, team performance, and building a culture of readiness, subscribe to In the Heart of Care. Available now, wherever you get your podcasts.

    Quince
    Go to Quince.com/curb for free shipping on your order and three hundred and sixty-five -day returns.
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    1 h y 4 m
  • #492 Hair and Nails with Helena Pasieka MD MS

    #492 Hair and Nails with Helena Pasieka MD MS
    Jul 21 2025
    Combing through common dermatologic complaints in Primary Care

    Hone your framework for assessing generalized and patchy hair loss and learn how to counsel patients about the hair loss advice they hear on social media. We discuss useful tests and treatments, psychosocial factors in relation to hair loss, variations in hair types and mention relevant nail conditions.

    Claim CME for this episode at curbsiders.vcuhealth.org!

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    Show Segments

    • Intro
    • Examination of hair and nails, ethnic hair types and cultural hair styles and practices.
    • Lab tests- clinically useful tests, and those to avoid
    • Telogen Effluvium
    • Scaly itchy scalp, seborrheic dermatosis, psoriasis
    • Androgenic alopecia and age-related hair loss
    • Topical and oral treatments
    • Examining the nails, conditions related to nail polishes and prosthetics
    • Patchy hair loss, alopecia areata, Discoid Lupus Erythematosis
    • Dr Pasieka’s take home points
    • Outro

    Credits

    • Written & Produced by: Kate Grant MBChB, MRCGP
    • Show Notes, Infographic & Cover Art : Kate Grant MBChB, MRCGP
    • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Reviewer: Leah Witt MD
    • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Technical Production: PodPaste
    • Guest: Helena Pasieka MD MS

    Disclosures

    Dr. Pasieka reports no relevant financial disclosures. Dr. Pasieka’s views are her own and do not represent those of her employer or the department of defense.

    The Curbsiders report no relevant financial disclosures.

    Sponsor:     Continuing Education Company

    Curbsiders listeners get 45% off select online courses—that’s the biggest discount CEC has ever offered, and it’s exclusive to you with promo code Curb45, through July 30. You can also use Curb30 for 30% off all webcasts and on demand replay courses. Check it all out at CMEmeeting.org/curbsiders.

    Sponsor: FIGS

    Curbsiders listeners can get 15% off. Just go to wearFIGS.com and use code FIGSRX.

    Sponsor Freed

    Use code: CURB50 to get $50 off your first month when you subscribe!
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    1 h y 29 m
  • PATREON UNLOCKED #39 Exclusive! Travel Medicine

    PATREON UNLOCKED #39 Exclusive! Travel Medicine
    Jul 17 2025
    Matt and Paul recap top pearls from a recent episode on Travel Medicine with Dr. Boghuma Titanji (audio version) and share their picks of the week. Below are links to the original interview & show notes.
    #449 Travel Medicine

    Picks of the week:
    Paul recommends: Clutch - Psychic Warfare; Harry Nilsson - The Point
    Watto - Mr. McMahon (Netflix Docuseries)
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    40 m
  • #491: Benign Hematology with Brad Beeler

    #491: Benign Hematology with Brad Beeler
    Jul 14 2025
    Decode low neutrophils, recognize thalassemia without chasing iron, and sharpen your approach to bleeding disorders in primary care.

    Crack the code on confusing labs. Learn from Dr. Bradley Beeler, an academic hematologist, how to recognize thalassemia without over-ordering tests, why a low neutrophil count in a healthy patient might not be a problem, and how to tackle bleeding disorders in primary care.

    Claim CME for this episode at curbsiders.vcuhealth.org!

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    Show Segments

    • Intro
    • Case 1: Duffy-null associated neutrophil count
    • Case 2: Bleeding disorders
    • Case 3: Thalassemia
    • Outro

    Credits

    Written and produced by Paul Wurtz MD. Show notes, cover art, and infographic also created by Paul Wurtz MD.

    • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Reviewer: Sai S Achi MD, MBA, FACP
    • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
    • Technical Production: PodPaste
    • Guest: Bradley Beeler MD

    Disclosures

    Dr. Beeler reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.


    Sponsor:     Panacea

    Search The Podcast for Doctors (By Doctors) on Spotify, Apple Podcasts, or wherever you listen.

    Sponsor:     Locumstory

    Locumstory.com is simply a free, unbiased educational resource about locum tenens.

    Sponsor:     Continuing Education Company

    Curbsiders listeners get 45% off select online courses — that’s the biggest discount CEC has ever offered, and it’s exclusive to you with promo code Curb45, through July 30. You can also use Curb30 for 30% off all webcasts and on demand replay courses. Check it all out at CMEmeeting.org/curbsiders.
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    1 h y 19 m