Hot flashes, mood swings, and brain fog. Too often, these symptoms are brushed off as inevitable signs of aging. What if these are your client’s early warning system of deeper hormonal chaos already underway?

In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with hormone specialist and bestselling author Dr. Mariza Snyder to discuss the critical phase of perimenopause. Long before menopause sets in, subtle shifts in hormone function can disrupt mood, metabolism, sleep, and more.

If you’re only testing estrogen and progesterone, you’re missing the bigger picture. This conversation challenges outdated assumptions and exposes the hidden patterns that masquerade as anxiety, depression, and burnout, so you can catch the real root cause before it’s too late.

The Silent Phase That Sets the Stage

Why the most critical hormonal changes start years before menopause and go unnoticed by most providers.

The Missing Piece in Hormone Testing

A key hormone marker that can reveal perimenopausal shifts early but is rarely measured.

When Stress Becomes the Master Hormone

How modern life drives the adrenal-hormone feedback loop and what to watch for in burned-out clients.

The Blood Sugar–Estrogen Link

Why metabolic balance is non-negotiable for hormonal balance and how to spot trouble before it spirals.

What Most Practitioners Miss About HRT Timing

The real risks of waiting too long and why “not yet” can be just as dangerous as “not at all.”

• Download the transcript here
• Download our FREE guides:
• Metabolic Health Guide here.
• Protein Charts
• Join the Next-Level Health Practitioner Facebook group here for free resources and community support
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.
• Check out other podcast episodes here
• 
  

• Visit Dr Mariza’s website: www.drmariza.com
• Check out her books here
• Grab her Free Hormone Quiz + Gifts: https://www.drmariza.com/hormone-quiz
• Listen to her podcast: Essentially You with Dr. Mariza Snyder
• Find her on social media platforms:
• Follow her on Instagram: @drmariza
• Facebook: @drmarizasnyder
• Insta: @drmariza
• YouTube
• Twitter: @drmariza

What if the first signs of metabolic breakdown aren’t in the pancreas or the blood sugar but hidden deep in the liver?

In this episode of ReInvent Healthcare, Dr. Ritamarie takes you inside the metabolic feedback loop few practitioners are trained to detect. Long before glucose rises or A1C shifts, subtle signals in the liver may already be pointing to a much bigger problem. They’re easy to miss, unless you know where to look. Discover the early biochemical whispers of insulin resistance, the hidden drivers of liver fat accumulation, and the lab markers most clinicians overlook. If your clients “look normal” on paper but still struggle, this is the episode you can’t afford to skip.

• The silent organ shift that can signal metabolic trouble before blood sugar ever changes
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• A hidden fat-making process your body might be running without your consent
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• How a sweet addiction quietly derails liver function and energy production
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• The overlooked lab markers that whisper metabolic distress long before diagnosis
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• A little-known score that could change how you assess “normal” labs
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• Simple but strategic actions that tip the scales from fatty liver to functional health
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• How small shifts in timing and nutrients may unlock powerful liver regeneration
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• Why stable glucose isn’t the full story, and the signal you might be missing

• Download our FREE Metabolic Health Guide here.
• Here is a FIB-4 Calculator Tool
• FIB-4 = (Age × AST) / (Platelets × √ALT)
• NAFLD fibrosis score (NFS) = -1.675 + (0.037 × age) + (0.094 × BMI) + (1.13 × hyperglycemia) + (0.99 × AST/ALT ratio) - (0.013 × platelet count) - (0.66 × albumin)
• Join the Next-Level Health Practitioner Facebook group here for free resources and community support
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.

Check out other podcast episodes here

What if your client’s labs show everything is “normal,” but their symptoms are screaming otherwise? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with holistic nutritionist and restorative wellness practitioner Divya Gupta to uncover the hidden truths behind thyroid dysfunction.

Drawing from her own journey with Hashimoto’s and gallbladder surgery—while juggling a high-stress corporate career—Divya reveals the overlooked patterns that block healing, the functional markers that actually matter, and how personalized nutrition can change the trajectory of thyroid health.

This conversation is a wake-up call for any practitioner who wants to go beyond the TSH trap and uncover what the body is really trying to say.

The “Normal” Lab Lie

A common lab result that’s often misread—and why it could be delaying your client’s healing.

Thyroid Clues in Disguise

What symptoms and organ systems often point to thyroid dysfunction before the labs ever do.

The Gallbladder-Thyroid Connection

Why losing this one organ may set off a hormonal cascade—and what most providers miss in post-op recovery.

How Corporate Stress Masks as Chronic Fatigue

What happened when one high-achieving woman finally decoded her burnout—and why it’s more common than you think.

Functional Testing That Speaks the Truth

Which labs and lifestyle markers Divya trusts most to uncover hidden patterns in thyroid and metabolic dysfunction.

• Download our FREE guides:
• Get the Optimize Thyroid Function Guide here.
• Get the Cardiovascular Risk Assessment here.
• Join the Next-Level Health Practitioner Facebook group here for free resources and community support
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.
• Check out other podcast episodes here

• Find Divya on her Website: divyagupta.net
• Instagram: _divgupta
• Facebook: Divya Gupta
• Download her Free Guide: Hypothyroidism Symptoms & Labs Guide

About Divya Gupta

Board Certified Holistic Nutritionist & Restorative Wellness Practitioner, Divya helps ambitious professionals create healthier futures than their parents experienced through personalized functional nutrition. Having overcome her own health challenges—gallbladder removal and Hashimoto's—while balancing corporate demands, she understands the limitations of conventional healthcare.

Her personal transformation fuels her passion for guiding clients to reclaim their well-being. When...

What if a key regulator of blood sugar, fat storage, and insulin sensitivity was hiding in plain sight, active only in the dark?

In this episode of ReInvent Healthcare, Dr. Ritamarie explores one of the most overlooked hormonal players in metabolic function. It’s not a supplement, not a medication, and not a superfood, but it profoundly influences metabolic health. It plays a role in glucose uptake, mitochondrial health, and inflammatory balance. You’ll discover how this nighttime signal impacts leptin and insulin and why testing and personalization matter more than ever.

If your clients are doing “all the right things” and still struggling with stubborn weight or glucose spikes, this might be the missing piece.

• A deep dive into the circadian hormone that influences insulin sensitivity and mitochondrial function
• How nighttime habits, light exposure, and stress blunt metabolic recovery
• The unexpected impact of this hormone on appetite regulation and fat storage
• Why common supplement protocols may backfire without genetic context
• Nutrient and lifestyle strategies that enhance endogenous production safely
• Testing options to assess hormonal circadian alignment and insulin response

• Download the transcript here
• Download our FREE Metabolic Health Guide here
• Join the Next-Level Health Practitioner Facebook group here for resources and community support
• 
  
• Visit INEMethod.com for advanced practitioner training and clinical mentorship
• Explore other podcast episodes here
• 
  

• Reiter RJ, et al. Melatonin in mitochondria: roles in oxidative stress and aging. J Pineal Res. 2010.
• Cipolla-Neto J, et al. Melatonin and energy metabolism. Mol Cell Endocrinol. 2014.
• Lane JM, et al. MTNR1B gene variant and glucose metabolism. Diabetes. 2016.
• Tuomi T, et al. MTNR1B variants impair beta-cell function. Cell Metab. 2016.
• Anderson G, et al. Melatonin’s role in insulin sensitivity. Sleep Med Rev. 2015.
• Gómez-Abellán P, et al. Circadian rhythms and metabolic regulation. Int J Obes. 2020.
• Arendt J. Human circadian rhythms and melatonin. J Endocrinol. 2005.

Khan A, et al. Cinnamon improves glucose and lipid metabolism. Diabetes Care. 2003.

What if your patient’s persistent symptoms aren’t fully explained by labs, imaging, or even your best root-cause protocols? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with rheumatologist-turned-integrative-healer Dr. Isabelle Amigues to explore the deeper messages the body is trying to send—through pain, illness, and resistance to healing.

Drawing from her unique lens as both a Western-trained physician and a stage IV cancer thriver, Dr. Amigues unpacks the emotional and energetic patterns she believes often underlie autoimmune disease, chronic pain, and unexplainable fatigue. This conversation challenges conventional clinical thinking and invites practitioners to go beyond the physical and into the subtle—but powerful—world of body-based wisdom.

• What Traditional Labs Are Missing
• The surprising clues hiding in plain sight when test results don’t explain your client’s symptoms.
• A Hidden Language of Healing
• Why some patients respond to treatments others don’t—and how the answer may lie beyond the physical.
• The Unexpected Roots of Chronic Illness
• A silent influence that can drive inflammation, fatigue, and autoimmunity—without ever showing up on a lab report.
• A Case Study That Changes Everything
• What happened when one physician applied this overlooked approach to her own life-threatening diagnosis.
• How to Listen When the Body Speaks
• The skillset every practitioner needs to uncover what standard protocols never address.

• Download the transcript here
• Download our FREE Guide: Immune Modulation Strategies Guide
• Join the Next-Level Health Practitioner Facebook group here for free resources and community support
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.
• Check out other podcast episodes here
• 
  

Dr. Isabelle Amigues’ Resources & Links:

• Visit Isabelle’s website at www.unabridgedMD.com
• Get her free meditation resource
• Follow her on Instagram
• Check out her TEDx talk
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Bio

Isabelle Amigues, MD, is a rheumatologist based in Denver, Colorado. She honed her expertise by studying in Paris, as well as at Columbia University in New York City. At age 40, she was diagnosed with stage IV metastatic breast cancer. A timely meeting with a non-traditionally trained practitioner taught her a different approach to disease, where she experienced the power of meditation,...

If your clients are gaining weight in their 40s or 50s despite clean eating and regular movement, it’s not simply “aging” or “hormones.”

In this episode of ReInvent Healthcare, Dr. Ritamarie explores a metabolic adaptation that occurs during midlife and alters how the body responds to glucose, insulin, and stress. There’s a multi-system shift that rewires fat storage, energy production, and appetite regulation.

What if one of the most overlooked drivers of insulin resistance in women is also one of the most correctable?

• A surprising hormonal connection that rewires the body’s response to glucose and insulin
• Why most blood sugar protocols fall short in midlife and what’s often missing
• The under-discussed cascade that turns food into fat even when eating “healthy”
• How specific plant-based foods and herbs can influence metabolic rhythm
• Why personalizing protocols is non-negotiable during this life stage
• Key markers to watch when tracking metabolic shifts in women 40+

• Download our FREE Metabolic Health Guide here
• Join the Next-Level Health Practitioner Facebook group here for resources and community support
• Visit INEMethod.com for advanced health practitioner training and clinical mentorship
• Check out other podcast episodes here
• 
  

• Barros RP, Gustafsson JÅ. Estrogen and metabolic regulation. Cell Metab. 2011.
• Mauvais-Jarvis F. Estrogen and androgen receptors in metabolic disease. Nat Rev Endocrinol. 2015.
• Khan A, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care. 2003.
• Zhang Q, et al. Berberine reduces insulin resistance and improves glucose metabolism. Metabolism. 2008.

Li SS, et al. Flaxseed and hormonal modulation in women. Nutrients. 2021.

Are hot flashes just an inconvenience—or a warning sign of deeper dysfunction? In this episode of ReInvent Healthcare, Dr. Ritamarie Loscalzo sits down with triple board-certified hormone expert Dr. Lorraine Maita to challenge outdated myths around hormone replacement therapy (HRT) and menopause care.

From debilitating mood swings and memory lapses to hidden bone loss and cardiovascular risks, Dr. Maita reveals why conventional medicine is failing midlife women—and what functional practitioners must do differently. If you’ve ever wondered if you should recommend HRT, how to test properly, or how to prepare the body for hormones, this conversation is a must-listen.

The Hot Flash Red Flag:

Why menopausal symptoms are more than a nuisance—and what they’re really signaling about your health.

The Hormone Testing Trifecta:

What Dr. Maita uses to map hormone metabolism—and why timing is everything.

What To Do First:

The critical step most practitioners skip before adding hormones—and how other conditions can make or break outcomes.

Estrogen’s Bad Reputation—Debunked:

The real story behind the Women’s Health Initiative study and bioidentical estrogen’s safety..

Beyond the Bandaid:

Why functional practitioners must stop swapping pills for supplements—and start building personalized, root-cause strategies.

When HRT Goes Wrong:

Why pellets can backfire, when progesterone alone is enough, and how even “natural” hormones can go toxic if pathways are blocked.

• Grab Our Free Guide to Unlock the Power of Optimal Energy
• Join the Next-Level Health Practitioner Facebook Group for free tools and training
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice
• Explore More Episodes on hormone balancing on ReInvent Healthcare and Functional Endocrinology here

• Visit The Feel Good Again Institute for courses and coaching
• Explore her medical practice at Vibrance for Life
• HRT4U Course and Ultimate Hormone Reset: Course Links Here
• Follow Dr. Maita on:
• Facebook
• Instagram
• LinkedIn
• YouTube

What if your clients’ metabolic struggles weren’t just related to insulin, cortisol, or diet but a deeper, overlooked hormone that bridges the gap?

In this episode of ReInvent Healthcare, Dr. Ritamarie pulls back the curtain on one of the most underestimated players in metabolic function: oxytocin. You’ll discover why this “feel-good” hormone is far more than a bonding chemical and why ignoring it could mean missing a key piece in your client’s healing.

If you aren't factoring in connection, community, and nervous system regulation, you might be overlooking one of the most powerful metabolic modulators nature has to offer.

• The Connection Between Love and Glucose
• What science reveals about the link between emotional connection and blood sugar balance.
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• Why More Protein and Exercise Aren’t Always the Answer
• How ignoring this hormone could cause your best health plans to fall flat.
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• The Secret Saboteur of Metabolic Recovery
• A hidden form of stress that blocks oxytocin and what to do about it.
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• Natural Ways to Boost This Overlooked Hormone
• How to stimulate oxytocin through functional strategies.
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• Join the Next-Level Health Practitioner Facebook group here for free resources and community support
• Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results.

Check out other podcast episodes here