Episodios

  • Lifestyle and Cognitive Health: A discussion with Drs. Elizabeth Kensinger and Andrew Budson

    Lifestyle and Cognitive Health: A discussion with Drs. Elizabeth Kensinger and Andrew Budson
    May 1 2025
    Elizabeth Kensinger, PhD and Andrew Budson, MD explain how healthy lifestyle habits, memory offloading strategies, and turning facts into stories can support cognitive aging. They stress that enriching and novel activities are more effective for brain health than most apps. Dr. Budson supports the theory that beta amyloid defends against brain infections, linking it to viral triggers of Alzheimer's. He also highlights new drugs like lecanemab and donanemab that may slow early Alzheimer's progression and potentially prevent its onset.
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    15 m
  • Could measles become endemic in the U.S. again within 25 years?

    Could measles become endemic in the U.S. again within 25 years?
    Apr 30 2025
    A JAMA model warns measles could become endemic in the U.S. within 21 years if MMR vaccination rates don't rise, with over 850,000 projected cases. A Phase 3 NEJM trial found brensocatib reduced exacerbations in non-CF bronchiectasis. An EPIC study correlated higher breast cancer risk to higher education levels, beyond lifestyle and reproductive factors.
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    5 m
  • What does Mexico’s first fatal H5N1 avian flu case tell us about current risks to humans?

    What does Mexico’s first fatal H5N1 avian flu case tell us about current risks to humans?
    Apr 22 2025
    Mexico’s first fatal H5N1 case involved a healthy child and highlights localized risk despite low global concern. Long-term antidepressant use was linked to higher sudden cardiac death risk, especially in younger adults. A U.S. study found 25% of adults with very high LDL cholesterol lacked statin treatment. These stories reveal persistent gaps in infection control, cardiac monitoring, and preventive care.
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    5 m
  • Could genetic testing improve prostate cancer screening beyond PSA?

    Could genetic testing improve prostate cancer screening beyond PSA?
    Apr 15 2025
    A polygenic risk score significantly improved prostate cancer detection beyond PSA testing, identifying more treatable and aggressive cancers in high-risk men. New WHO guidelines aim to reduce global meningitis deaths by standardizing early diagnosis, treatment, and care across settings. GLP-1 receptor agonists and SGLT2 inhibitors were linked to reduced Alzheimer's risk, with GLP-1s showing the most consistent neuroprotective effects in recent studies. Lastly, breast cancer mortality was 47% higher among Black women living in disadvantaged neighborhoods, underscoring the impact of social determinants on survival.
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    6 m
  • Mary Beth Cicero on Reimagining the IUD: A Painless Future for Contraception

    Mary Beth Cicero on Reimagining the IUD: A Painless Future for Contraception
    Apr 10 2025
    Mary Beth Cicero, co-founder of Three Daughters, shares how her passion for women's health led to the development of a new frameless, self-assembling magnetic IUD designed to significantly reduce the pain of insertion and retrieval. The device, inspired by embryo transfer techniques and using copper as its active ingredient, aims to improve comfort, eliminate strings, and offer a more body-conforming contraceptive option—especially for younger women deterred by current IUDs. As the product moves through clinical trials, the team is focused on both efficacy and ease of use, with hopes to expand into treating other uterine conditions in the future.
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    19 m
  • Could a shingles vaccine delay dementia more effectively than current medications?

    Could a shingles vaccine delay dementia more effectively than current medications?
    Apr 8 2025
    A large study in Wales found that older adults who received the shingles vaccine had a 20% lower risk of developing dementia over seven years, with the strongest effect seen in women. U.S. measles cases have surged past 500, driven largely by outbreaks in West Texas and linked to international travel, underscoring critical gaps in vaccination coverage. Meanwhile, new research shows that even the wealthiest Americans have shorter life expectancies than their European peers, pointing to systemic health disadvantages in the U.S.
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    5 m
  • HER2+ Lung Cancer Treatment: Past, Present, and Future

    HER2+ Lung Cancer Treatment: Past, Present, and Future
    Apr 2 2025
    Drs. Yu and Sabari trace the evolution of HER2-mutant lung cancer treatment from chemotherapy to targeted therapies, highlighting key advancements, challenges, and patient responses. They also explore emerging treatment strategies, resistance mechanisms, and the future of personalized therapy based on biomarkers and co-mutations.
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    10 m
  • Can statins reduce liver cancer risk in patients with chronic liver disease?

    Can statins reduce liver cancer risk in patients with chronic liver disease?
    Apr 1 2025
    A study published in JAMA Internal Medicine found that statin use in patients with chronic liver disease was associated with a lower risk of liver cancer and hepatic decompensation, suggesting potential protective effects beyond lipid management. Surveys by the Annenberg Public Policy Center revealed widespread misinformation about the risks of consuming raw milk, highlighting the need for public education on the importance of pasteurization. New research links red meat allergy (alpha-gal syndrome) to bites from deer ticks and western black-legged ticks, expanding the geographic risk area and emphasizing the need for clinicians to consider this diagnosis in patients with unexplained allergic symptoms following tick bites.
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    5 m
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