We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Tiffany Callahan, Lead Architect of Agentic AI Systems at SandboxAQ. As a physicist, I love her approach to Large Quantitative Models trained on physics, chemistry, biology, and math to model the real world.

Most of the companies in this space are building statistical models by:

• integrating large datasets for target identification by analyzing genomic and multi-omic data
• virtual screening to identify promising drug candidates
• novel molecule design and property prediction (toxicity, efficacy, pharmacokinetics)
• clinical trial optimization through patient selection and outcome prediction
• drug repurposing by finding new uses for existing drugs

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• Tell me about SAIR.
• Who are your customers?
• How do you create value?
• How do you capture value from customers?
• What are three things you want to do for your customers in the next 12-18 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Jeff Gombala, Founder and CEO at Evidexa. Jeff Gombala started Helios Innovation with an idea that seems obvious – use expert knowledge and AI models to validate healthtech and medtech products.

We’re going to talk about Jeff’s journey, the value they are creating, how they’re turning that into a business, and where they want to take customers by 2026.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• How do you create value for your customers?
• How do you capture value?
• What are three things you’d like to achieve for your customers in the next 12 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is David Lazerson, Co-Founder and CEO at Briya.

Briya started in 2020 with a bold idea — using cryptography and zero-knowledge proofs to make healthcare data shareable, secure, and compliant. Fast forward to today, they’ve just launched Briya AIRE, a clinical-grade AI research platform that promises to let researchers ask questions in plain English and get scientifically robust answers back — without writing code.

We’re going to talk about David’s journey, the value Briya is creating, how they’re turning that into a business, and where they want to take customers by 2026.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• What made you start with something as gnarly as zero-knowledge proofs for healthcare data?
• At what point did you realize infrastructure wasn’t enough, that people wanted insights, not just secure pipes?
• What customer conversations tipped you off that AI was the next layer?
• For a researcher using AIRE, what’s the moment when the lightbulb goes on?
• Which use case best shows the value — the one where you thought, ‘okay, this is working’?
• How quickly can a researcher go from a question in plain English to a publishable-level output?
• Validation is one thing — but startups live or die on turning that into repeatable business. What did you have to prove to your Series A investors to show Briya could cross that chasm?
• I know you probably can’t share exact revenue, but when investors leaned in, what was the strongest signal they saw that Briya wasn’t just another pilot project? Contracts signed, pipeline size, or something else?
• If we sit down again in 18 months, what would you want to point to as real traction?
• What’s the one thing you think customers will be most surprised that Briya can do for them by 2026?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Shai Melcer, Head of the National Program for Bioconvergence at The Israel Innovation Authority. We kick this episode off by first learning what bioconvergence is. Then we talk about who The Israel Innovation Authority’s customers are. Next, we examine why this is such a unique opportunity for Israel. But no opportunity is without its competition, so we talk about how Melcer is competing with cyber and defense — which are huge sectors here. Melcer then also shares how he is competing against big companies like Sandbox AQ. Next, we discuss how The Israel Innovation Authority creates and captures value. Lastly, we conclude this episode with Melcer sharing three things he wants to do for his customers.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• What is bioconvergence?
• Who are your customers?
• Why is this a unique opportunity for Israel?
• How do you compete with cyber and defense, which are huge sectors here?
• How do you compete with companies like Sandbox AQ, which spun off from Google quantum computing, raised $950M, and just released the largest publicly available binding affinity dataset with co-folded 3d structures on Hugging Face?
• How do you create value?
• How do you capture value from your customers?
• What are 3 things you want to do for your customers?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Yann Gaston-Mathé, Co-Founder and CEO at Iktos.

Iktos combines AI drug discovery with a robot chemist – AI designs novel compounds considering synthesis constraints, and robots automatically synthesize compounds (100 reactions in parallel vs 2 manual).

Trained as a mathematical engineer, Yann Gaston-Mathé crossed from numbers into biology, carrying a belief that drug discovery could be faster, smarter, and more humane. With Iktos, he’s bringing that vision to life — combining generative AI and robotics to redesign how medicines are designed, made, and tested, with the goal of delivering better therapies in less time.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• Tell me about Iktos.
• Who are your customers?
• How do you create value?
• How do you capture value from customers?
• What are 3 things you want to do for your customers in the next 12-18 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is James Hamrick, MD, MPH, Chairman of the Caris Precision Oncology Alliance at Caris Life Sciences. By combining massive amounts of genomic, transcriptomic, and proteomic data with clinical outcomes, Caris has created one of the largest and most comprehensive multimodal databases of combined molecular and clinical outcomes data in the world – more than 600,000 matched patient records and growing.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• How do you create value for your oncology treatment center partners in the POA?
• How do you capture the value?
• What are 3 things you’d like to achieve for your customers in the next 12 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Aaron Brauser, General Manager Life Sciences at Carta Healthcare.

AI should work in synergy with clinical expertise. This “Hybrid Intelligence” approach propelled Carta Healthcare to become a leader in clinical data abstraction, serving health systems and pharma companies. Their platform leverages a combination of AI, LLMs, and clinically guided expert models to analyze EHR data in real time, instantly matching patients to clinical trials. Additionally, the solution captures and makes available all the key clinical data from the unstructured notes to allow it to be imported back into the EMR, improving research and other clinical uses.

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• How do you create value for your drug company customers?
• How do you capture the value?
• What are 3 things you’d like to achieve in the next 12 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!

We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Tim O’Connell, Founder and CEO at emtelligent. Tim O’Connell and Anoop Sarkar started emtelligent in 2016 with a need that Tim had (and still has) as a practicing radiologist. How do you take the massive volume of unstructured text in healthcare and put it into a clean, structured format?

Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

• Tell me about your journey.
• How do you create value for your drug and device customers?
• How do you measure the value?
• What are 3 things you’d like to achieve in the next 12 months?

Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

• Apple Podcasts
• Spotify
• iHeartRadio
• Amazon Music
• Pandora
• YouTube

Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

Thanks so much for listening!