What exciting times! Clinical trials into the management of SAB! SNAP publication on the horizon!

But how do we interpret and apply the results of these trials to our patients? This week Jame and Callum are joined by Dr Clark Russell, Clinical Lecturer in Infectious Diseases to discuss:

1. The difficulty in interpreting current clinical trials in SAB.
2. The emerging concept of "low risk" SAB and how to define this.
3. The heterogeneity of SAB and how this might be exploited.

Notes for this episode here: https://idiots.notion.site/107-SAB-update-1316a1ea09d8800ba701ca7ebc8d4093

Previous episodes for the basics of Staphylococcus aureus and SABATO & SNAP trials:

1. It starts with Staph

65. SNAP trial protocol

72. SABATO trial & 73. SABATaddendum

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Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.

In this, part 1 of 2 on diagnostics we discuss the use of biomarkers such as beta-D-Glucan and galactomannan, as well as serology and molecular techniques.

Notes for this episode can be found: here.

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.

In this, part 1 of 2 on diagnostics we discuss the use of microscopy, histopathology and culture in diagnosing fungal infections.

Notes for this episode can be found: here.

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app!

Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod

IT'S A BREAKPOINTS BREAKOUT!

Jame and Callum are joined by the drugnamic duo of Julie-Ann Justo & Erin McCreary from the Breakpoints podcast to delve into the IDSA DTR Gram negative Guidance.

Show notes for this episode are here.

Breakpoints podcast can be found here: https://breakpoints-sidp.org/

Lyrics:

Tryin’ to use some drugs to kill these bugs

Erin and Julie are PK PD thugs

Gonna make these two ID:IOTS look like mugs

It’s gonna be a Breakpoints Breakout

Sorry the song sounds so tinny, Podcast host is doing something strange to it. Link to original MP3 here.

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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My my! Mycology?

Join Callum and special co-host Alyssa for this, the first in the all new ID:IOTS Mycology Mega-series.

Here we cover:

1. What the British Society of Medical Mycology is and what they do
2. Why we're doing this series on fungi
3. The Global and UK Burden of fungal disease.
4. The spectrum of fungal disease clinically,
5. The taxonomy of these pathogens,
6. and the WHO Fungal Pathogen List.

Notes for this episode can be found here.

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app!

Feel like giving back? Donations of caffeine gratefully received!
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So now, Loyal Listener, you know all about Susceptible, Sensitive at higher doses, Resistant, MICs, ECOFFs/ECVs and how to use the EUCAST breakpoints table....

But what about the wild-west of bug-drug combos where there are no breakpoints?

Well in this episode, Jame and Callum talk through the EUCAST approach to this situation.

Show notes for this episode here

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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BREAKPOINTS. We all love them. S breakpoints... R breakpoints... dash, IE, NA...

Wait, dash, IA, NA, Brackets?!

LISTEN ON (and read the accompanying prep notes), and soon you'll know! In this episode Jame and Callum talk through the EUCAST breakpoints table and how to interpret it

Show notes for this episode here

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Jame is joined by Kate from BioMérieux as they take a deep dive into the BCID2 and the Vitek Reveal, 2 new devices used for rapid identification and antimicrobial susceptibility testing of blood culture isolates.

Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.

Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directly

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod