When two different studies came out looking at the association of type 2 diabetes and Alzheimer's risk, we knew we had to dig in! What exactly are the risks? What is the connection? Do any medicines help negate those risks? Joey has the details.

What's in the Bottle? Whey Protein Essentials! It's an easily digested, low-carb source of 25 grams of pure whey protein isolate. The blend contains all 9 essential amino acids, concentrated levels of BCAAs, and no added sugars. Getting enough protein can be tough. Whey Protein Essentials can give you the boost you need

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
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Questions - questions@askjoedimatteo.com
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Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:32 - Study: Type 2 Diabetes & Alzheimer’s
02:55 - Study Summary
07:42 - Study: Diabetes Meds & ALZ Risk
09:41 - Study Summary
11:09 - GLP-1 and SGLT-2 impact on dementia
14:35 - Obesity & Alzheimer’s
16:58 - What’s in the Bottle: Creatine Essentials
17:47 - What is Creatine?
20:02 - Who is creatine supplementation for?
25:01 - Are there risks?
28:20 - How do you use Creatine Essentials?
30:31 - Show Outro

SHOW NOTES:
1) Type 2 Diabetes Rewires the Brain (NeuroscienceNews) - https://tinyurl.com/4skhvcs5
2) Diabetes Rewires the Brain (Pharmacy Times) - https://tinyurl.com/yszyksey
3) Diabetes drugs may slash Alzheimer's risk (MedicalNewsToday) - https://tinyurl.com/tjmxmrmy
4) GLP-1, Parkinson’s Disease (The New England Journal of Medicine) - https://tinyurl.com/465njwjv
5) Treatment for people with Parkinson's disease (Lancelet) - https://tinyurl.com/yjunh4s6
6) BCAAs on Muscle During Exercise (NIH) - https://tinyurl.com/2dpbz9vu
7) Whey protein as a source of peptides (Research Gate) - https://tinyurl.com/4wfz937u
8) Protein - Which is Best? (NIH) - https://tinyurl.com/3athvss8
9) Health Benefits of Whey Protein (ResearchGate) - https://tinyurl.com/mry4mvh4
10) Whey protein isolate attenuates strength decline (NIH) - https://tinyurl.com/2d44pa5w
11) Functional properties of whey (NIH) - https://tinyurl.com/mr48wuff
12) Relevance of whey protein (ScienceDirect) - https://tinyurl.com/p7p2uf8n

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

Josiah unintentionally set us up for a conversation about a fantastic new study: Do you REALLY need a coach or trainer if you want to start exercising? Will they actually make a difference? That was the question a new study asked and the answer was a resounding "YES!"

In “What’s in the Bottle?,” Joey explains exactly how the body responds to stress, and particularly chronic stress. From there, he explains the use cases for each of our adrenal support products, Adrenal Advanced Essentials & Stress Support Essentials. What you need depends entirely on where you are in the chronic stress response!

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:32 - Show Intro
00:58 - Josiah's Marathon Experience
07:27 - Coaching Study
11:39 - Punchline
12:57 - How were the findings measured?
17:04 - What’s in the Bottle: Adrenal Supplements
18:15 - What is stress?
20:59 - Cortisol
23:13 - DHEA
23:53 - Adrenal Advanced Essentials
26:01 - Adaptogenic Herbs
28:12 - Vitamin Blend
28:51 - Dosing
29:48 - Adrenal Calm Essentials
30:37 - What's in ACE?
33:21 - Dosing
34:36 - How these differ from other supplements
38:27 - Show Outro

SHOW NOTES:
1) Impact of Coach Behavior (Study) - https://tinyurl.com/2epv5bxt
2) Rhodiola Rosea (Study) - https://tinyurl.com/2aehvtk9
3) Trial of SHR-5 Rhodiola Rosea Doses (Study) - https://tinyurl.com/bddmp5z8
4) Stimulating Effect of SHR-5 on Students (Study) - https://tinyurl.com/39j6ecza
5) Iron Advanced Essentials (Ask Joe DiMatteo) - https://tinyurl.com/trrc8smy
6) Eleutherococcus senticosus (Study) - https://tinyurl.com/mvua6a46
7) Heavy Exercise & Adaptogens (Study) - https://tinyurl.com/33c7x6nf
8) ESP-102 improves memory (Study) - https://tinyurl.com/4hv9fwdd
9) Chronic Stress and HPA Axis (Study) - https://tinyurl.com/55z593w5
10) Vit C and Adrenals (Study) - https://tinyurl.com/mryuxpex
11) Pantothenic Acid & Glutathinone (Study) - https://tinyurl.com/4929fpma

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

How is your brain affected by what you (over) eat? We examine a study which shows that even a brief period of overeating ultra-processed, high-calorie snacks can lead to lasting disruption in the brains insulin response & liver fat accumulation.

Behind the Counter, shocking almost no one, science proves that weed makes you dumber.

“What’s in the Bottle?,” you ask? Iron Advanced Essentials! Iron supports prenatal and cognitive health, as well as energy balance.

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CONNECT:
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Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:31 - Show Intro
00:39 - Behind the Counter
03:26 - Discussion: Insulin & Obesity Risk
03:49 - Brain insulin and obesity risk
04:41 - How does insulin work?
05:34 - Insulin sensitivity
07:03 - Insulin and the brain
08:38 - The study
16:54 - What’s in the Bottle: Iron Advanced Essentials
17:42 - What's in the update?
18:50 - Why would you take this supplement?
20:47 - How do we get iron from our diet?
21:52 - Energy Balance
22:38 - What's in Iron Advanced Essentials?
23:55 - Dietary Intake of Iron
25:39 - How do you become deficient in iron?
28:54 - Dosage
31:16 - Show Outro

SHOW NOTES:
1) Birth & Brain Growth (Article) - https://tinyurl.com/mrnz7cu2
2) Cannabis Reduces Brain Activity (Article) - https://tinyurl.com/57cec8zh
3) Rapid Dietary Effects on Brain Insulin and Obesity Risk (Article) - https://tinyurl.com/4dhs3vus
4) Brain Insulin & High Calories (Study) - https://tinyurl.com/bdcrhk93
5) Iron Advanced Essentials (Ask Joe DiMatteo) - https://tinyurl.com/trrc8smy
6) Dietary Reference Intakes (NIH) - https://tinyurl.com/48tfycdf
7) Iron metabolism in man (NIH) - https://tinyurl.com/3ypzyym7
8) Physiology and molecular biology of iron absorption (NIH) - https://tinyurl.com/yydnztek
9) Absorption of heme iron (NIH) - https://tinyurl.com/bdhkmbfc
10) Bioavailability of minerals in legumes (NIH) - https://tinyurl.com/put2zfda
11) Approaches to improve iron bioavailability from complementary foods (NIH) - https://tinyurl.com/bmejns2w
12) Iron absorption from the whole diet in men (NIH) - https://tinyurl.com/4mykhexe
13) Iron nutrition and absorption (NIH) - https://tinyurl.com/3avx6np6
14) Iron supplementation in menstruating women with low ferritin (NIH) - https://tinyurl.com/4uv5mby7
15) Prevent and Control Iron Deficiency in the U.S. (CDC) - https://tinyurl.com/23f3ncux

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

You don't see this very often! The FDA has REMOVED a "black box warning" from testosterone products used in TRT and other hormone therapies. The FDA uses box warnings when there is serious concern about a potential side effect. Seeing one removed is almost completely unheard of!

Joey and Dante break down all the details on what's changing, the research behind it, and what it means for the millions of men using testosterone replacement therapy.

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CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:25 - Show Intro
01:26 - Unrelated Question
05:26 - Discussion: FDA Changing labeling on TRT
10:31 - How often does the FDA remove warnings?
13:11 - More about the study
16:50 - Dosing in the study
22:14 - VA study
26:22 - Show Outro

SHOW NOTES:
1) FDA Issues New Labeling (Article) - https://tinyurl.com/2nsu7rvy
2) FDA Official Announcement - https://tinyurl.com/4xh5skz5
3) Cardiovascular Safety of TRT (Study) - https://tinyurl.com/4xmaf7mt
4) VA study of TRT & CV (Study) - https://tinyurl.com/46exs6da

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

When a doctor suspects plaque build-up in the arteries and vessels of a patient's heart, a non-invasive CT scan will often be used to detect the presence of calcium. That results are represented as a Calcium Score (Coronary Artery Calcium or CAC).

So if the results come back and you have a low or even zero CAC, you're safe, right? Unfortunately, it's not that easy. Dante has the details based on a listener question.

Joey gives us details on a product with a VERY specific use: Prenatal Complete with DHA! Creating life is not the time to use just any old prenatal, and Joey explains the details of why ours is worth the investment!

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

SHOW NOTES:
1) The Zero CAC Paradox (Study) - https://tinyurl.com/2pd476yp

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

Is obesity a disease or does it lead to disease? Or is it merely a corollary with disease? What exactly is obesity? Where is the cutoff... and why?

With questions like this raging in the medical community and popular-health world, the Lancet pulled together dozens of doctors and scientists to try and bring clarity based on the broadest and most well-established research. What they came up with is both critically important... and difficult to parse for the non-professional.

This episode is extra long, but with obesity (and clinical obesity) comprising the single greatest challenge for Americans and the health of their families, we decided it was worth it!

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:34 - Show Intro
01:22 - Unrelated Question
04:18 - Article: Is Obesity a disease state?
06:04 - What was the definition of obesity?
09:27 - What is the new definition of obesity?
10:55 - How is it diagnosed?
15:18 - What are the downsides of calling obesity a disease?
19:37 - Pre-clinical vs. clinical obesity
28:37 - FDA Indications for obesity medications
35:23 - Public perception of obesity
44:28 - Waist circumference
48:10 - Body roundness index
49:18 - Show Outro

SHOW NOTES:
1) Definition & Diagnosis of Obesity (Lancet) - https://tinyurl.com/y6bnkwjs
2) Is obesity a disease? (Economist) - https://tinyurl.com/mrxrmtja

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

Joey digs into a new study linking prenatal exposure to FPAS via contaminated drinking water to an increase in childhood cancer. We unpack the research and discuss what women can do to protect their babies. This research has huge implications for young families!

After that, Joey tells us exactly what's so exciting about one of our newest products, Ovarian Advanced Essentials. Designed to target women's hormone issues, Ovarian Advanced Essentials is built with the exact ratios of D-chiro Inositol and myoinositol that have been shown in research to the most help, particularly to women with PCOS. When hormones become unbalanced, the symptoms can be wide-ranging. Don't miss the chance to set things straight naturally!

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:31 - Show Intro
01:34 - Study: Prenatal exposure to PFAs in drinking water
01:53 - What are PFAs?
04:22 - What health risks to PFAs pose?
09:31 - What do we do about PFAs?
14:17 - WitB: Ovarian Advanced Essentials
14:45 - What are ovaries?
15:08 - What does OAE do?
15:48 - Who is it for?
16:46 - What is PCOS?
20:37 - Study
23:31 - What is in OAE?
23:48 - Inositol
26:11 - Other nutrients
27:55 - Dosing
28:49 - Show Outro

SHOW NOTES:
1) PFAS and Childhood Cancer - https://tinyurl.com/bddtfxu9
2) PFAS & Cancer (Study) - https://tinyurl.com/3x2barmn
3) Ovulation in PCOS (Study) - https://tinyurl.com/3pnn5jzx

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

We field a question from a listener about her husband’s Ambien use and dive into all things related to sleep aids. Watch for the good, bad, and the ugly of sleeping pills and other remedies for a better night’s sleep!

Behind the counter, researchers further explain how Metformin scientifically helps Type 2 diabetes patients and does even more than that! Plus, does gut microbiome affect behavior? We examine a study that compares incarcerated women who are considered impulsive and violent and those who aren't.

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:25 - Show Intro
03:15 - Behind the Counter
06:27 - Viewer Question: Ambien & Alternatives
07:33 - Why is Ambien causing these issues?
08:48 - What are peak plasma levels and “clearance?"
15:27 - How is the alcohol affecting this situation?
18:53 - Could diet be a contributing factor?
19:57 - Why should someone take Ambien?
22:59 - Is it typical to stay on Ambien this long?
27:29 - Alternatives to using Ambien
29:39 - Other pharmacological options
31:23 - What does it look like to taper off Ambien?
33:29 - Supplements for sleep
35:03 - Show Outro

SHOW NOTES:
1) Unmasking Metformin (SciTechDaily) - https://tinyurl.com/5dhnb2zz
2) Impulse Control (Karger) - https://tinyurl.com/6b5duhrv

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.