Episodios

  • It Takes a Village
    May 8 2025

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Marlen Lauffer, M.D.
    • Dalila Sabaredzovic
    • David Silver, PhD
    • Roxana Redis, Ph.D.
    • David Fischer, Ph.D.
    • Tim Yu, M.D., PhD

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    41 m
  • Scaling n-of-1 Therapies: From One to Many
    Mar 24 2025

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Steven Ringel
    • Jeff Milton
    • Scott Demarest, M.D.
    • Marlen Lauffer, M.D.
    • Annemieke Aartsma-Rus, Ph.D.

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    54 m
  • Beyond the Data: Author Insights on N-of-1 Trials in Precision Medicine
    Mar 11 2025

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Scott Demarest, M.D.
    • Tim Yu, M.D., PhD
    • Olivia Kim-McManus, M.D.
    • Richard Finkel, M.D.

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    50 m
  • Visionary Science: Charting a Path for Mutation-Based Retinal Interventions
    Jan 6 2025

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Rob Collin, Ph.D.
    • Roger Paxton, Ph.D.
    • Scott Henry, Ph.D.
    • Annemieke Aartsma-Rus, Ph.D.
    • Tim Yu, MD, PhD

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    38 m
  • Molecules and Methods: Reevaluating ASO Biodistribution to the Brain
    Sep 26 2024

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Charles Berde, M.D., Ph.D.
    • Joseph Madsen, M.D.
    • Bryn Martin, Ph.D.
    • Kathrin Meyer, Ph.D.
    • Roxana Redis, Ph.D.
    • Willeke can Roon-Mom, Ph.D.

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    40 m
  • Behind the Publication: Author Insights on 'How to Pay for Individualized Genetic Medicines'
    Aug 30 2024

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, our featured guests discuss the topic of "How to Pay for Individualized Genetic Medicines"

    • Timothy Yu, M.D., Ph.D.
    • Andrew Lo, Ph.D.
    • Julia Pian, M.D.
    • Deanna Portero, MPH/MBA Candidate

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    38 m
  • Smarter Ways to Identify Treatment Targets
    Jul 8 2024

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Logan Newton, M.S.
    • Annemieke Aartsma-Rus, Ph.D.
    • Bush, Lynn, Ph.D., M.S. Bioethics, M.A.
    • Marlen Lauffer, M.D.
    • Willeke van Roon-Mom, Ph.D.

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

    Más Menos
    39 m
  • Finding the Balance: Urgency, Rigor, and Uncertainty in Lead Optimization
    Jun 17 2024

    Fireside Chats in Individual Medicines brings together experts at the forefront of individualized medicines to have candid discussions about relevant topics and practical challenges involved in advancing these pioneering therapies. In this episode, we feature:

    • Casey McPherson
    • Jennifer San Miguel, Ph.D.
    • Michael Templin, Ph.D., DABT
    • Roxana Redis, Ph.D.
    • Willeke van Roon-Mom, Ph.D.
    • Robert Cabrera, Ph.D.

    Fireside Chats in Individualized Medicines is a podcast hosted by the N=1 Collaborative. This podcast is the work product of the N=1 Collaborative, a group of researchers and practitioners who share their expertise and experience in individualized medicine. This podcast hosts individuals from multiple organizations and is intended to provide information for research and educational purposes only and is expressly not intended to provide legal, clinical, or professional advice which should be sought separately by qualified practitioners. The information and views shared in the podcast are based on the best available knowledge and practice at the time of publication. The N1C reserves the right to update, modify, or withdraw content at any time without prior notice. Listeners of these podcasts should exercise their own judgment and discretion in applying these practices to their specific situations.

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    42 m