This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright revisit the critical topic of endocrine disruptors—chemicals in our environment that interfere with hormones and impact metabolism, weight, and overall health.

Dr. Cooper breaks down how everyday exposures to substances like phthalates, BPA, and others can have generational effects on metabolic pathways and disease risk. The episode highlights the link between these chemicals and the rising rates of obesity, diabetes, and even cancer, while offering practical steps for minimizing exposure in daily life.

Key Takeaways:

• Endocrine disruptors are chemicals found not only in food but in everyday items such as furniture, makeup, plastics, and baby products, making exposure widespread and difficult to avoid.
• These chemicals can mimic or block hormones, disrupting critical metabolic and developmental processes, with effects that may pass to future generations.
• Regulatory oversight in the U.S. is decreasing, with significant EPA budget cuts threatening existing screening and cleanup programs targeting endocrine-disrupting chemicals.
• Air quality improvements, especially through HEPA filtration, and making informed choices during preconception, pregnancy, and early childhood, can help reduce exposure.
• Consumer awareness, advocacy, and using resources like the Environmental Working Group (EWG) app are key strategies for individuals seeking to lower risk.

Personal Stories & Practical Advice:

• Andrea shares the everyday struggle to find safe, affordable alternatives and the surprise of seeing improvements in metabolic hormone levels after changing air filters and reducing workplace exposures.
• Dr. Cooper discusses strategies to minimize risk during critical windows such as preconception and pregnancy, and emphasizes the power of informed consumer choices in driving safer product development.

Resources from the episode:

• Environmental Working Group (EWG) resources and app for product safety ratings
• U.S. EPA Endocrine Disruptor Screening Program (EDSP)
• PubMed for scientific research on specific chemicals (BPA, phthalates, PFAS)
• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.

Fat Science is supported by the non-profit Diabesity Institute, which aims to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright tackle the frustrations of navigating the American healthcare system—especially when it comes to treating metabolic dysfunction, diabetes, and obesity. Mark vents about insurance obstacles, while Dr. Cooper breaks down how short-term thinking, excessive profit layers and lack of preventive care put patient health at risk.

Andrea and Dr. Cooper share personal stories and expertise about the high cost and complexity of accessing vital medications. Together, they explore how incentives, policies, and profit motives harm patient outcomes and propose ideas for a system that truly values health over profits.

Key Takeaways:

• The U.S. healthcare system appears to prioritize short-term profits over long-term health, making it hard for patients to access necessary preventive treatments.
• Insurance companies create barriers to care by denying medications until a patient’s condition worsens, favoring “sick care” over prevention.
• The cost of medications in the U.S. is often exponentially higher than in other countries due to lack of price negotiation and excessive middlemen.
• Access to essential drugs often depends on your employer, state, or industry, creating inequities for those outside favored sectors.
• Real cost savings—and better outcomes—come from investing in prevention and allowing providers and patients to make informed decisions without interference.

Personal Stories & Practical Advice:

• Mark and Andrea describe fights with insurance for medication access, including resorting to Canadian pharmacies and out-of-pocket payments.
• Dr. Cooper explains how prevention in her clinic has reduced heart attacks, strokes, and new cases of diabetes among her high-risk patients.

Resources:

• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.

Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright uncover the truth about fatty liver disease and its rapid rise in both adults and children. It’s estimated 125 million Americans have the disease.

Dr. Cooper explains the critical role the liver plays in metabolism—covering hundreds of essential functions—and why fatty infiltration poses serious risks. The episode demystifies diagnosis, risk factors, and treatment options, empowering listeners to take a proactive approach to liver health and metabolic wellness.

Key Takeaways:

• Fatty liver disease, now known as MASLD—Metabolic Dysfunction-Associated Steatotic Liver Disease, affects about 30% of adults, and is rising in youth, especially those with obesity or type-2 diabetes.
• Risk is not limited to higher body weights; up to 15% of normal-weight people are also affected, with genetics playing a significant role.
• Diagnosis can be tricky: blood enzymes (ALT, AST) and platelet counts factor into the highly predictive FIB-4 score, while imaging (like fibroscan) provides clarity on severity.
• Untreated, fatty liver can progress to inflammation, fibrosis, and even require a liver transplant, though early-stage disease is often reversible with proper intervention.
• Treatment focuses on improving metabolic function—through medication, diabetes management, and sometimes lifestyle changes—as solely relying on diet and exercise may not be enough, particularly for advanced cases.

Personal Stories & Practical Advice:

• Andrea shares her own experience discovering fatty liver disease and seeing rapid improvement after metabolic treatment.
• The hosts discuss common misconceptions, and why liver health should be checked in both children and adults, regardless of body size or outward health.

Resources:

• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.

Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the concept of “male menopause” and whether it’s backed by science. Dr. Cooper breaks down hormonal changes in men, including testosterone decline, metabolic dysfunction, and the myths surrounding andropause.

The episode dives into why men and women experience aging differently, how metabolism ties into hormone shifts, and what really happens to male fertility and energy over time. After listening, you’ll understand why “male menopause” isn’t the full story and what really matters for men’s health as they age.

Key Takeaways:

• There’s no sudden “male menopause”—testosterone declines gradually in men, unlike the rapid hormonal changes seen in female menopause.
• Metabolic dysfunction can suppress testosterone in men, leading to fatigue, muscle loss, and changes in body fat distribution.
• Converting testosterone to estrogen in belly fat can further suppress testosterone, creating a cycle that impacts energy and mood.
• Testosterone therapy might be beneficial for some men with low levels, but should always be guided by a healthcare provider after thorough evaluation.
• Most supplements marketed to “boost testosterone” are unproven and potentially unsafe—focus on medical advice and proper testing.

Personal Stories & Practical Advice:

• Mark shares his journey with testosterone treatment and how restoring balance improved his mood and energy.
• Andrea and Dr. Cooper discuss the importance of understanding individual lab results, getting the full metabolic picture, and consulting with primary care providers before considering hormone therapy.

Resources:

• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.

Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore the expanding world of telehealth in treating metabolic issues. Dr. Cooper sheds light on both the promise and pitfalls of accessing medications like GLP-1s through online platforms. The episode dives into the effectiveness of patient-provider relationships, the importance of comprehensive and personalized care, and the potential red flags in impersonal telehealth services. After listening, you’ll understand the benefits of telehealth and why thoughtful, thorough medical guidance is crucial for metabolic health.

Key Takeaways:

• Telehealth has improved accessibility and convenience for metabolic care, but not all platforms offer the same quality of support.
• The lack of personalized interaction and lab-based assessments in many telehealth services can pose risks to patient health.
• Quick, transactional telehealth models often prioritize medication sales over holistic care and ongoing patient monitoring.
• Comprehensive care requires detailed history-taking, follow-up, and lab work—elements often missing in mass-market telehealth.
• Listeners should watch for red flags such as no direct provider interaction, absence of lab testing, and subscription models tied to product sales.

Personal Stories & Practical Advice:

• Andrea reflects on her own journey and the difference a dedicated, whole-person approach made to her health.
• Dr. Cooper shares her experience testing a mass-market telehealth site, exposing the superficial nature of some programs.
• The panel urges listeners to seek out board-certified providers and reputable telehealth organizations for genuine care.

Link to US National telehealth clinics with Board Certified Obesity Medicine providers: Knownwell (non-affiliated)

Resources:

• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org ordr.c@fatsciencepodcast.com.

Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

This week on Fat Science, Dr. Emily Cooper, Andrea Taylor, and Mark Wright explore why metabolic health transformations require time, persistence, and a holistic approach. Andrea shares her 14-year journey with Dr. Cooper, highlighting the slow, individualized nature of healing a dysfunctional metabolism and why quick fixes rarely work.

Dr. Cooper explains how complex feedback loops, hormonal adaptations, and life events can slow progress—and why health markers, not just the number on the scale, are crucial measures of success. The conversation encourages patience, self-compassion, and a focus on sustainable health, not just rapid weight loss.

Key Takeaways:

• Healing metabolic dysfunction is a complex, highly individualized process that often takes years—not weeks or months.
• Dieting, stress, disrupted sleep, and misguided exercise can send the body into "famine mode," making weight loss even harder.
• Metrics like blood pressure, cholesterol, and glucose often improve before significant weight loss occurs—these health gains matter.
• Medications and bariatric surgery can help in stubborn cases, but long-term success depends on a combination of medical, lifestyle, and psychological support.
• As many as 20% of patients may be "non-responders" to current treatments, highlighting the need for ongoing metabolic research and new therapies.

Personal Stories & Practical Advice:

• Andrea details her long road—from early GLP-1 medications and plateaus to bariatric surgery and ongoing adjustments—with the emphasis that patience paid off.
• Dr. Cooper and Mark reinforce the importance of redefining food as fuel and joy, not the enemy, and letting go of blame or unrealistic expectations tied to the scale.
• The episode highlights small wins, the value of routine lab work, and celebrating all forms of progress—especially the non-scale victories.

Resources:

• Connect with Dr. Emily Cooper on LinkedIn.
• Connect with Mark Wright on LinkedIn.
• Connect with Andrea Taylor on Instagram.

Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.

If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at info@diabesityinstitute.org or dr.c@fatsciencepodcast.com.

Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/