Do hot-flashes increase your risk of dementia? What hormonal changes are doing to your brain.

Join Dr. Nally as he discusses the newest information about women's hormones and your brain.

Listen as Dr. Nally debunks the recent American College of Cardiology findings regarding use of a ketogenic diet and increased heart disease risk.  Why is this the worst medical article Dr. Nally has ever read?  Listen and find out.  We also talk about the labs you should be watching and closely following while in a ketogenic or carnivorous lifestyle.  

Check out Dr. Nally's Cholesterol Mini-Course at https://www.docmuscles.com/cholesterol/

#Cholesterol #STATIN #LDL #Creatine #Diet #Food #FoodIsMedicine #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck #Muscles #NoBSsm #Exercise

References:

1. ACC Annual Scientific Session News Article - https://www.acc.org/latest-in-cardiology/articles/2023/03/01/22/45/sun-1215pm-kctogenic-acc-2023

Don't miss this podcast as Dr. Nally discusses the sugar alcohol, erythritol, and what the Cleveland Clinic's study really means to those following a Ketogenic Lifestyle.  Is there another reason behind attacking erythritol?  After hearing this podcast, you decide.

#Erythritol #Polyols #HeartDisease #Stroke #Diet #Food #FoodIsMedicine #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck

#Gorgeous #Muscles

Show notes:

1. Witkowski, M., Nemet, I., Alamri, H. et al. The artificial sweetener erythritol and cardiovascular event risk. Nat Med (2023). https://doi.org/10.1038/s41591-023-02223-9
2. Bornet FRJ, Blayo A, Dauchy F, Slama G. Plasma and Urine kinetics of Erythritol after Oral Ingestion in Health Humans. Reg Toxicol Pharm. 0ct 1996. 24(2):S280-S285.  https://doi.org/10.1006/rtph.1996.0109
3. Proctor and Gamble partners with Clevland Clinic and their heart lab to develop a heart disease biomaker in Nov 2022. https://www.marketscreener.com/quote/stock/PROCTER-GAMBLE-COMPANY-4838/news/Procter-Gamble-Partners-with-Cleveland-Clinic-Cleveland-HeartLab-to-Develop-Heart-Disease-Biomar-38269523/
4. Molino G, Avagnina P, Cavanna A, Ballarè M, Torchio M, Bona B, Belforte G. Sorbitol clearance: a parameter reflecting liver plasma flow in the rat. Res Commun Chem Pathol Pharmacol. 1986 Apr;52(1):119-32. PMID: 3715193.
5. Polyol Diagram - https://www.researchgate.net/figure/Fig-2-Schematic-of-the-Polyol-Pathway-blue-shaded-area-and-its-links-to-the_fig2_5630519

With the recent explosion in popularity of the GLP-1 agonist medications for obesity, Dr. Nally discusses a little known problem (muscle loss) becoming more significant with these drugs popularity. 

If you've ever considered using any of these medications in this class, you'll want to tune in to this podcast. 

#GLP1 #semaglutide #dulalutide #tirzepatide #liraglutide #exanatide #sarcopenia #Diet #Food #FoodIsMedicine #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck #Muscles #Cytokines #incretin #NoBSsm #Exercise

References:

1. Wilding JPH, et al. STEP 1 Study Group of the Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med 2021; 384:989-1002.  DOI: 10.1056/NEJMoa2032183.
2. McCrimmon, R.J., Catarig, AM., Frias, J.P. et al. Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial. Diabetologia 63, 473–485 (2020). https://doi.org/10.1007/s00125-019-05065-8

Dr. Nally talks about creatine and all of its benefits.  Since it's Valentines, he discusses how ketosis and creatinine can fix a broken heart.  You don't want to miss this one.

#Creatine #Diet #Food #FoodIsMedicine #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck #Skin #Skincare #BeautifulSkin #SkinCarePrimer #Face #Gorgeous #Muscles #Cytokine

References:

1. Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol. 2018 Jul 15;108:166-173. doi: 10.1016/j.exger.2018.04.013. Epub 2018 Apr 25. PMID: 29704637; PMCID: PMC6093191.
2. Kreider RB. Effects of creatine supplementation on performance and training adaptations. Mol Cell Biochem. 2003 Feb;244(1-2):89-94. PMID: 12701815.
3. Kreider RB, Stout JR. Creatine in Health and Disease. Nutrients. 2021 Jan 29;13(2):447. doi: 10.3390/nu13020447. PMID: 33572884; PMCID: PMC7910963.

Dr Nally gives the answers to the Egg IQ quiz and answers questions about the causes of persistent elevated blood sugars while following a ketogenic or carnivorous lifestyle.

Body Weight Exercise Program: https://q0y908pr.pages.infusionsoft.net

Weight Management & Concierge Medicine: https://www.DocMuscles.com/membership/

#Glucose #Cytokines #BloodSugar #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck #PicoSure #Icon #SculpSure #TempSure #EMScuptNeo #EMSella #EMFace  #Skin #Skincare #BeautifulSkin #SkinCarePrimer #Face #Gorgeous

#NoBSsm #Muscles #Myokines #Exercise

References:

1. Li Y et al., J Diabetes Res. May 2013. Online. ID 170532, p1-8
2. Sonksen P, Sonksen J. Brit J. Anaesth. July 2000. 85(1): 69-79
3. Nieto-Vazquez, I et al., Archieves of Physiol Biochem. 2008. 114(3): 183-194
4. Cook CJ, Phys Behav, Sep 2004, 82:4; 751-762
5. Herman, J P et al. Braz Jour Med Biol Res, Mar 2012, 45:4; 292-8
6. McEwen, B., Neuropsychopharmacol, 2000 22:108–124.
7. Khan S, Shafiei MS, Longoria C, Schoggins J, Savani RC, Zaki H. SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway. bioRxiv [Preprint]. 2021 Mar 17. Update in: Elife. 2021 Dec 06:10.

Dr. Nally's checks your Egg IQ asking you five questions about eggs.   Send your answers and your T-shirt size to questions@docmuscles.com. The first person to correctly answer will win a free DocMuscles.com T-Shirt.  

Dr. Nally talks about how a pen and notepad can change your memory in just 66 days.  You're not going to want to miss this one.  

Dr. Nally's Favorite Leather Notebook Cover: https://amzn.to/3JQyX7Z

Dr. Nally's Favorite Moleskin Journal: https://amzn.to/3YxKf5H

Show Note References:

1. Umejima K, Ibaraki T, Yamazaki T, Sakai K. Paper notebooks vs mobile devices: Brain activation differences during memory retrieval.  Front. Behav. Neurosci., 19 March 2021(15). https://doi.org/10.3389/fnbeh.2021.634158
2. Vanderbilt University, Treadway M, Zald D. Dopamine impacts your willingness to work.  Journal of Neuroscience 2 May 2012.

Listen as Dr. Nally discusses the hormonal effects on weight loss caused by exercise.  He explains why resistance type exercise or HIIT exercise is so very important in a weight loss program.  

You can download a copy of his body weight exercise program for free at https://www.docmuscles.com/exercise

Myokines and Weight loss blog post: https://www.docmuscles.com/myokines-and-weight-loss/

Show Note References:

1. Pedersen BK. Muscles and their myokines. J Exper Biol. 2011. 214:337-346.  doi:10.1242/jeb.048074.
2. Furuichi Y, Manabe Y, Takagi M, Aoki M, Fujii NL (2018) Evidence for acute contraction induced myokine secretion by C2C12 myotubes. PLoS ONE 13(10): e0206146. https://doi.org/ 10.1371/journal.pone.0206146.
3. Han LJ & Hee-Sook J. Role of Myokines in Regulating Skeletal Muscle Mass and Function. Frontiers in Physiology. Jan 2019. Vol 10:1-9. doi: 10.3389/fphys.2019.00042
   
   #LeadFolloworGetOutOrMyWay #JustKeepEsterifying #Ketogenic #Keto #KetogenicLifestyle #Carnivore #DrAdamNally #DocMuscles #DocMusclesLive #DocTalk #DocsWhoLift #LiftRunShoot #DocMusclesLife #PlantBasedDietsSuck
   Dr Nallys Lasers: #PicoSure #Icon #SculpSure #TempSure #EMScuptNeo #EMSella #EMFace  
   #NoBSsm #Muscles #Myokines #Cytokines #BDNF #Exercise