From Breakthrough to Blockbuster
The Business of Biotechnology
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From Breakthrough to Blockbuster
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Narrado por:
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Chris Andrew Ciulla
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Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources.
Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs.
From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
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Historia4.5 out of 5 stars 28
Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
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4 out of 5 stars
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Book is interesting but narrator is not
- De Alexa en 05-05-23
De: Barry Werth
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Immune
- A Journey into the Mysterious System That Keeps You Alive
- De: Philipp Dettmer
- Narrado por: Steve Taylor
- Duración: 10 h y 28 m
- Versión completa
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General5 out of 5 stars 1,291
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Narración:5 out of 5 stars 1,105
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Historia5 out of 5 stars 1,098
You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.
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5 out of 5 stars
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Steve Taylor for the win
- De Bay Area Engineer en 11-02-21
De: Philipp Dettmer
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- De: Thomas Hager
- Narrado por: Angelo Di Loreto
- Duración: 8 h y 39 m
- Versión completa
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General4.5 out of 5 stars 4,929
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Narración:4.5 out of 5 stars 4,265
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Historia4.5 out of 5 stars 4,247
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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4 out of 5 stars
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Engrossing to physicians & lay persons alike
- De C. White en 03-08-19
De: Thomas Hager
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The Song of the Cell
- An Exploration of Medicine and the New Human
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 16 h y 3 m
- Versión completa
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General4.5 out of 5 stars 878
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Narración:4.5 out of 5 stars 743
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Historia4.5 out of 5 stars 737
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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5 out of 5 stars
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Beyond Words Wonderful
- De Lynn en 11-27-22
Lo que los oyentes dicen sobre From Breakthrough to Blockbuster
Calificaciones medias de los clientesReseñas - Selecciona las pestañas a continuación para cambiar el origen de las reseñas.
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Total5 out of 5 stars
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Ejecución5 out of 5 stars
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Historia5 out of 5 stars
- Fox2
- 11-12-22
Excellent description of the biotech industry
Fantastic book describing the biotech industry from its beginning to now. Engaging and recommended to read or listen.
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Total2 out of 5 stars
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Ejecución3 out of 5 stars
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Historia2 out of 5 stars
- Anonymous User
- 09-12-23
Nothing to learn for pharma professionals
Nice introduction to the world of pharma R&D, but those who’ve been in the business have probably heard the stories many times already.
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