Letting the rest of the world go by
I know not everyone will love the book, but I did and I know some others will too. Usually I don't like predictions about the future since the future is so hard to see accurately but I think Kurzweil does such an outstanding job. If statements like the universe will become self aware one day after man biologically merges with our thinking machines bother you, you probably shouldn't bother with this book, but if such statements excite you the book could be worth your trouble.
Even though it's published in 1999 the book is still useful today. I was reluctant to get it because I though it might be dated. He really does explain the human genome better than anything I've read. The book was a necessary background to educate me about all of this talk I've been hearing about the human genome. Some of his assertions haven't held up since the publication of the book, but don't let that dissuade you from reading this highly informative book.
Easy to follow book on the changing nature of facts and how they help make our current foundation for science. He illustrates his points by many great vignettes such as why even today spinach is falsely believed to contain a lot of iron. That story alone makes the book worth a listen.