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Leonardo da Vinci created the two most famous paintings in history, The Last Supper and the Mona Lisa. But in his own mind, he was just as much a man of science and engineering. With a passion that sometimes became obsessive, he pursued innovative studies of anatomy, fossils, birds, the heart, flying machines, botany, geology, and weaponry.

Following his blockbuster biography of Steve Jobs, The Innovators is Walter Isaacson’s revealing story of the people who created the computer and the Internet. It is destined to be the standard history of the digital revolution and an indispensable guide to how innovation really happens. What were the talents that allowed certain inventors and entrepreneurs to turn their visionary ideas into disruptive realities? What led to their creative leaps? Why did some succeed and others fail?

Benjamin Franklin is the founding father who winks at us - an ambitious urban entrepreneur who rose up the social ladder, from leather-aproned shopkeeper to dining with kings. In best-selling author Walter Isaacson's vivid and witty full-scale biography, we discover why Franklin turns to us from history's stage with eyes that twinkle from behind his new-fangled spectacles. In Benjamin Franklin, Isaacson shows how Franklin defines both his own time and ours. The most interesting thing that Franklin invented, and continually reinvented, was himself.

By the time Henry Kissinger was made secretary of state in 1973, he had become, according to a Gallup poll, the most admired person in America and one of the most unlikely celebrities ever to capture the world’s imagination. Yet Kissinger was also reviled by large segments of the American public, ranging from liberal intellectuals to conservative activists. Kissinger explores the relationship between this complex man's personality and the foreign policy he pursued.

When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.

Based on more than 40 interviews with Jobs conducted over two years—as well as interviews with more than a hundred family members, friends, adversaries, competitors, and colleagues—Walter Isaacson has written a riveting story of the roller-coaster life and searingly intense personality of a creative entrepreneur whose passion for perfection and ferocious drive revolutionized six industries: personal computers, animated movies, music, phones, tablet computing, and digital publishing.

Six close friends shaped the role their country would play in the dangerous years following World War II. They were the original best and brightest, whose towering intellects, outsize personalities, and dramatic actions would bring order to the postwar chaos, and whose strong response to Soviet expansionism would leave a legacy that dominates American policy to this day. In April 1945, they converged to advise an untutored new president, Harry Truman.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a closely related molecule that enables the genetic instructions coded in DNA to express themselves.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

This national best-seller chronicles the true story of two brothers coming of age in the Henry Horner public housing complex in Chicago. Lafeyette and Pharoah Rivers are 11 and nine years old when the story begins in the summer of 1987. Living with their mother and six siblings, they struggle against grinding poverty, gun violence, gang influences, overzealous police officers, and overburdened and neglectful bureaucracies. Immersed in their lives for two years, Kotlowitz brings us this classic rendering of growing up poor in America’s cities.

In the days and months after Pearl Harbor, the lives of Japanese Americans across the continent and Hawaii were changed forever. In this unforgettable chronicle of war-time America and the battlefields of Europe, Daniel James Brown portrays the journey of Rudy Tokiwa, Fred Shiosaki, and Kats Miho, who volunteered for the 442nd Regimental Combat Team and were deployed to France, Germany, and Italy, where they were asked to do the near impossible. Brown also tells the story of these soldiers' parents, immigrants who were forced to submit to life in concentration camps on U.S. soil.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

In this explosive new book, Sam Harris tears down the wall between scientific facts and human values, arguing that most people are simply mistaken about the relationship between morality and the rest of human knowledge. Harris urges us to think about morality in terms of human and animal well-being, viewing the experiences of conscious creatures as peaks and valleys on a "moral landscape".

When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.

From trips on private jets and encounters with world leaders to shocking accounts of misogyny and double standards behind the scenes, this searing memoir exposes both the personal and the political fallout when unfettered power and a rotten company culture take hold. In a gripping and often absurd narrative where a few people carelessly hold the world in their hands, this eye-opening memoir reveals what really goes on among the global elite.

Based on more than 40 interviews with Jobs conducted over two years—as well as interviews with more than a hundred family members, friends, adversaries, competitors, and colleagues—Walter Isaacson has written a riveting story of the roller-coaster life and searingly intense personality of a creative entrepreneur whose passion for perfection and ferocious drive revolutionized six industries: personal computers, animated movies, music, phones, tablet computing, and digital publishing.

Naval Ravikant is an entrepreneur, philosopher, and investor who has captivated the world with his principles for building wealth and creating long-term happiness. The Almanack of Naval Ravikant is a collection of Naval’s wisdom and experience from the last 10 years, shared as a curation of his most insightful interviews and poignant reflections. This isn’t a how-to book, or a step-by-step gimmick. Instead, through Naval’s own words, you will learn how to walk your own unique path toward a happier, wealthier life.

In The Optimist, the Wall Street Journal reporter Keach Hagey presents the most detailed account yet of Altman’s rise, from his precocious childhood in St. Louis to his first, failed startup experience; his time as legendary entrepreneur Paul Graham’s protégé and successor as head of Y Combinator, the start-up accelerator where Altman became the premier power broker in Silicon Valley; the founding of OpenAI and his recruitment of a small yet superior team; and his struggle to keep his company at the cutting edge while fending off determined rivals, including Elon Musk.

Why we think it’s a great listen: You thought he was a stodgy scientist with funny hair, but Isaacson and Hermann reveal an eloquent, intense, and selfless human being who not only shaped science with his theories, but politics and world events in the 20th century as well. Based on the newly released personal letters of Albert Einstein, Walter Isaacson explores how an imaginative, impertinent patent clerk became the mind reader of the creator of the cosmos.

When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction, and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third.

Everyone is programmed a little differently, and Bill Gates' unique insight led to business triumphs that are now widely known: the twenty-year-old who dropped out of Harvard to start a software company that became an industry giant and changed the way the world works and lives; the billionaire many times over who turned his attention to philanthropic pursuits to address climate change, global health, and U.S. education.

J. Robert Oppenheimer was one of the iconic figures of the 20th century, a brilliant physicist who led the effort to build the atomic bomb but later confronted the moral consequences of scientific progress. When he proposed international controls over atomic materials, opposed the development of the hydrogen bomb, and criticized plans for a nuclear war, his ideas were anathema to powerful advocates of a massive nuclear buildup during the anti-Communist hysteria of the early 1950s.

Two-time winner of the Pulitzer Prize David McCullough tells the dramatic story behind the story about the courageous brothers who taught the world how to fly: Wilbur and Orville Wright.

On December 17, 1903, at Kitty Hawk, North Carolina, Wilbur and Orville Wright's Wright Flyer became the first powered, heavier-than-air machine to achieve controlled, sustained flight with a pilot aboard. The Age of Flight had begun. How did they do it? And why?

Following his blockbuster biography of Steve Jobs, The Innovators is Walter Isaacson’s revealing story of the people who created the computer and the Internet. It is destined to be the standard history of the digital revolution and an indispensable guide to how innovation really happens. What were the talents that allowed certain inventors and entrepreneurs to turn their visionary ideas into disruptive realities? What led to their creative leaps? Why did some succeed and others fail?

Suzanne Simard is a pioneer on the frontier of plant communication and intelligence; her TED talks have been viewed by more than 10 million people worldwide. In this, her first book, now available in audio, Simard brings us into her world, the intimate world of the trees, in which she brilliantly illuminates the fascinating and vital truths—that trees are not simply the source of timber or pulp, but are a complicated, interdependent circle of life.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave - "Really Achieving Your Childhood Dreams" - wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because "time is all you have... and you may find one day that you have less than you think").

From the New York Times bestselling author of Midnight in Chernobyl comes the definitive, dramatic, minute-by-minute story of the Challenger disaster, based on fascinating in-depth reporting and new archival research—a riveting history that flows like a thriller.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Adam Savage is a maker. From Chewbacca’s bandolier to a 1,000-shot Nerf gun, he has built thousands of spectacular projects as a special-effects artist and the cohost of MythBusters. Adam is also an educator, passionate about instilling the principles of making in the next generation of inventors and inspiring them to turn their curiosity into creation. In this practical and passionate guide, Adam weaves together vivid personal stories, original sketches and photographs from some of his most memorable projects, and interviews with many of his iconic and visionary friends.

With his characteristic eyebrow-raising behavior, Richard P. Feynman once provoked the wife of a Princeton dean to remark, "Surely you're joking, Mr. Feynman!" But the many scientific and personal achievements of this Nobel Prize-winning physicist are no laughing matter. Here, woven with his scintillating views on modern science, Feynman relates the defining moments of his accomplished life.

Wired called Dr. Fei-Fei Li “one of a tiny group of scientists—a group perhaps small enough to fit around a kitchen table—who are responsible for AI’s recent remarkable advances.” Known to the world as the creator of ImageNet, a key catalyst of modern artificial intelligence, Dr. Li has spent more than two decades at the forefront of the field. But her career in science was improbable from the start. The Worlds I See is the moving memoir of a scientist coming of age as an immigrant in America who finds her calling at the forefront of the AI revolution.

As Wall Street swooned and boomed through the last decade, our livelihoods have—now more than ever—come to rely upon the good sense and risk appetites of a few standout investors. And amidst the BlackRocks, Vanguards, and Berkshire Hathaways stands arguably the most iconoclastic of them all: SoftBank’s Masayoshi Son. In Gambling Man, the first Western biography of Son, the self-professed unicorn hunter, we go behind the scenes of the world’s most monied halls of power in New York, Tokyo, Silicon Valley, Saudi Arabia, and beyond.

"Are you one of us?" a patient once asked Marsha Linehan, the world-renowned psychologist who developed dialectical behavior therapy. "Because if you were, it would give all of us so much hope." Over the years, DBT had saved the lives of countless people fighting depression and suicidal thoughts, but Linehan had never revealed that her pioneering work was inspired by her own desperate struggles as a young woman. Only when she received this question did she finally decide to tell her story.