TWiP reviews the global, regional, and national burden of Chagas disease, and comparison of doxycycline and rifampicin for the treatment of onchocerciasis.

Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula

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• Burden of Chagas' disease (Lancet Inf Dis)
• Doxycycline vs rifampicin in treatment of river blindness (Open For Inf Dis)
• The kissing bug by Daisy Hernandez
• TWiP study – information and survey

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Music by Ronald Jenkees

TWiP solves the case of the man in his 60s experiencing weight loss, fatigue, and loss of appetite.

Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula

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• Hero: Bailey K. Ashford
• Letters read on TWiP 276
• TWiP study – information and survey

New Case

Male in his 20s from Hokkaido, Japan, developed fatigue and rash, followed by fever and myalgia 6 days later. He was a group of five individuals on a hunting trip prior to this and reports that 3 friends are just fine but one other individual developed similar symptoms. He reports that they had been hunting the Ussuri brown bear, which is larger and more aggressive than the Asian black bear. They had been successful and all five of them had consumed well cooked bear meat. He does share that he is aware of infectious risk from eating bear and thus the meat was well cooked. He and the one fellow hunter who did get sick were unique in that they each ate one of the eye balls raw. This is a tradition that is felt to give the consumer the great vision that these animals are purported to have.

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Music by Ronald Jenkees

TWiP reviews the effectiveness of long-lasting spatial repellent emanators against malaria in humanitarian crisis settings in northern Nigeria, and Dengue suppression by male Wolbachia-infected mosquitoes.

Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula

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• Spatial emanators for malaria control (Lancet Inf Dis)
• Dengue suppression with Wolbachia-infected mosquitoes (NEJM)
• Singapore Environmental Health Institute (TWiV 630)
• TWiP study – information and survey

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Send your questions and comments to twip@microbe.tv