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Despite incredible advances in diabetes technology, blood sugar control in people with Type 1 diabetes hasn’t meaningfully improved in over a decade. In this eye-opening episode recorded live at Metabolic Health Summit, Dr. Andrew Koutnik - a scientist, patient, and advocate - dives into the science behind this paradox.

Dr. Koutnik shares groundbreaking data from the largest-ever analysis of carbohydrate intake in people with Type 1 diabetes, explores the limitations of current technology, and presents a rare 10-year case study examining the long-term safety and efficacy of carbohydrate restriction.

From CGMs to closed-loop systems, from meal composition to insulin dosing, this episode challenges conventional assumptions and offers a compelling case for nutrition as a powerful - yet underutilized - tool in diabetes care.

Special thanks to the sponsors of this episode:

• Genova Connect – Get 15% off any test kit with code METABOLICLINK here
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In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

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Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

For more exclusive content on metabolic health and therapy, check out our membership platform for free: https://membership.metabolicinitiative.com

In this Journal Club edition of The Metabolic Link, hosts - Victoria Field, Dr. Dominic D’Agostino, and Dr. Angela Poff dissect two powerful papers reshaping our understanding of metabolic health. First up: a striking human study showing that exposure to sugar rationing during the first 1,000 days of life reduced the risk of type 2 diabetes and hypertension decades later—offering a rare glimpse into how early-life nutrition programs lifelong health. Then, the team dives into a landmark publication proposing a clinical research framework for ketogenic metabolic therapy in glioblastoma. With insights on developmental programming, public policy, and personalized metabolic approaches to cancer, this is a must-listen for anyone passionate about where science meets societal change.

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
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Read both papers here:

1. Exposure to sugar rationing in the first 1000 days of life protected against chronic disease
2. Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
• Facebook
• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

What’s really causing America’s obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model.

Moderated by host Dr. Dominic D’Agostino, the discussion dives deep into the biological roots of obesity, the relevance of sugar-sweetened beverages, the role of leptin and uric acid, and whether it’s fructose or calories that are driving the crisis. Despite their differing perspectives, both experts agree on one critical point—our modern food environment is fueling metabolic dysfunction on a massive scale.

This is one of the most nuanced and constructive conversations you’ll hear on the topic of obesity science.

References submitted by both guests can be found here!

For more exclusive interviews and presentations with Dr. Johnson and Dr. Norton along with 100s of other videos on metabolic health and therapy, ad-free private episodes of The Metabolic Link, and to earn CMEs visit our member medical education platform: https://membership.metabolicinitiative.com

Special thanks to the sponsors of this episode:
✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here
✅ iRestore – Get a huge discount when you use the code METABOLICLINK here
✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here

Learn more about Dr. Layne Norton
Learn more about Dr. Richard Johnson

In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

Find us on social:

• Instagram
• Facebook
• YouTube
• LinkedIn

Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.