Episodios

  • The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1274
    Apr 25 2025
    You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase • 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But what is it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows exactly how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You’ll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you’re traveling or don’t have access to the tech Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE’ for a discount – https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey’s Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 6 m
  • The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1275
    Apr 25 2025
    You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase• 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You’ll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you’re traveling or don’t have access to the tech Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE’ for a discount – https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey’s Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 6 m
  • The Real Reason You Still Feel Tired—Even When Your Bloodwork Looks Perfect | Dr Pompa : 1273
    Apr 24 2025
    Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy. Dr. Pompa shares his personal health collapse and reveals how cellular dysfunction, neurotoxicity, and hormone resistance drive the chronic fatigue epidemic. If you’ve ever felt dismissed by “perfect” bloodwork, this conversation will rewire how you think about sickness—and show you how to reclaim real, lasting wellness. What You’ll Learn in This Episode: • Why your bloodwork can be “perfect” while your cells are on fire • The overlooked hormone resistances sabotaging your energy and metabolism • The 3-legged stool of chronic illness—and what actually drives disease • What “upstream detox” really means, and why most cleanses make you worse • Why toxins trigger genetic expression (and how to shut that down) • How to fix unexplainable fatigue, anxiety, and weight gain from the inside out • Why true healing starts with fixing the cell, not the symptom It’s time to stop chasing symptoms—and start upgrading from the root. **Check out Dr. Pompas EXCLUSIVE protocol built for The Human Upgrade listeners at davetestkit.com and use code ‘10OFF’ for a discount!** SPONSORS -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dr. Pompa’s Website – https://drpompa.com/ • Dr. Pompa’s Instagram - https://www.instagram.com/drpompa/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:55 Intro • 01:10 Healthy Is the New Sick • 02:27 Bloodwork & Hormone Resistance • 04:32 Dr. Pompa’s Health Collapse • 08:38 Toxins & Environmental Triggers • 15:01 Why Most Detox Fails • 29:16 The 5 Rs of Cellular Healing • 37:06 Olive Oil: Cure or Concern? • 38:11 Fat Balance for Energy • 42:13 Cholesterol & Saturated Fat • 46:26 Restoring Cellular Energy • 51:08 The Power of Diet Variation • 56:57 Plant Toxins Explained • 01:03:28 Emotional & Spiritual Detox • 01:13:55 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 19 m
  • The $500 Billion Secret: Why Top Leaders Chase Stress | Sébastien Page : 1272
    Apr 22 2025
    Most people run from stress. The world’s highest performers run toward it. Sébastien Page manages over $500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance, clarity, and control. But here’s the twist: this isn’t just about boardrooms or billion-dollar trades. Whether you’re running a company, chasing a deadline, or just trying to stop procrastinating on your goals—this conversation will flip what you think you know about pressure, performance, and productivity. You’ll learn why trying to “relax your way to success” doesn’t work—and how to harness discomfort to create better decisions, higher output, and more resilience in every part of life. What You’ll Learn in This Episode: • The psychology of stress and why zero stress leads to burnout • How procrastination can boost creative performance • What astronauts, athletes, and leaders have in common • Why the key to better decisions is strategic patience, not speed • The stress-performance curve no one taught you in school • Why losing is the real path to mastery (and what Roger Federer can teach you) • The difference between being nice vs. being kind—and why it matters It's time to start turning stress into strategy. SPONSORS -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Sébastien’s New Book –The Psychology of Leadership – https://www.psychologyofleadership.net/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Intro • 02:00 Book Launch & Setup • 02:45 Buy or Sell? Market Insights • 03:20 Stress and Performance • 04:28 Sports Psychology Breakdown • 09:48 Federer & the Power of Losing • 26:42 Rethinking Feedback • 31:32 Stress as a Tool • 44:10 Listening as Leadership • 44:17 Traits of Great Leaders • 44:54 Psychology for Entrepreneurs • 45:37 Leading Beyond Work • 46:09 Sleep Tracking Anxiety • 47:39 Channeling Stress • 49:04 Extreme Pressure Moments • 50:42 The Corporate Athlete • 59:08 Vulnerability & Leadership • 01:05:23 Goal-Induced Blindness • 01:12:34 Finding Meaning at Work • 01:18:08 Leadership at Home • 01:20:27 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 20 m
  • Web3 & the Future of Genetics: AI, Blockchain & Data Ownership with Nillion : 1271
    Apr 17 2025
    Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. But what if there was a way to take it back… and hack the system? In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data. Together, they break down the Web3 tech stack powering this revolution. Enter Nillion, a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away. From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself. What You’ll Learn in This Episode: • Why your DNA is already in government databases—and how long they keep it • How Nillion enables secure computation on private data • What it means to build a “cybernetic operating system” for your body • Why Fulcra.ai is building the orchestration layer of human optimization • How Monadic DNA helps you profit from your genetics—without giving them away • Why owning your data is the next frontier of biohacking • The surprising connection between decentralization, health freedom, and consciousness • How to join the movement toward true data sovereignty If you’ve ever felt like you’re giving away too much to big tech, big pharma, or just the internet itself—this conversation will change how you see your data… and your body. **Join the Fulca sleep study today! Visit https://fulcra.ai/sleep to sign up** **Get a 30% discount on Fulca with code “DAVE”! SPONSORS -IGNITON | Go to https://www.biohackingconference.com/ and get your tickets while there are still great discounts available. Learn more at https://igniton.com/. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Fulcra Dynamics Website – https://www.fulcradynamics.com/ • MonadicDNA Website: https://monadicdna.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:01 – Intro • 02:26 – Data Privacy & AI: The Big Shift • 03:21 – Meet Michael Tiffany • 04:41 – Cybernetic Operating Systems • 05:13 – Wearables & Personal Augmentation • 08:21 – Meet Vishakh: DNA Privacy Mission • 09:25 – Why Genetic Data Needs Protection • 11:30 – New Tech: Encryption & Privacy Tools • 16:13 – How Multi-Party Compute Works • 41:58 – Emergence: Behavior & Systems • 49:11 – Meditation & Mental Reprogramming • 50:20 – Distributed Computing & Biology • 56:15 – Environment Shapes Potential • 57:57 – Empowering Individuals at Scale • 01:00:31 – Biohacking Meets Inner Awareness • 01:04:01 – The Dark Side of DIY Mind Hacks • 01:06:09 – Future of Biohacking & Community• 01:12:28 – Integrating Genetic & Life Data • 01:20:39 – Why We Started Biohacking • 01:25:01 – Favorite Current Biohacks • 01:31:41 – Final Thoughts & Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 30 m
  • Dr. Steven Gundry: Is Fungus Secretly Running the World—and Your Gut? : 1270
    Apr 15 2025
    If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours? In this mind-altering episode of The Human Upgrade, Dr. Steven Gundry reveals a startling new theory: your gut microbiome might be controlling your thoughts. From addiction and depression to obesity and inflammation, the microbes living in your gut—bacteria, fungi, viruses, even parasites—may be pulling the strings on your brain chemistry, mood, and behavior. Dave Asprey and Dr. Gundry dive deep into The Gut-Brain Paradox, exposing how the gut-brain axis operates more like a microbial command center than a digestive system. You’ll learn why probiotic pills rarely work, how the wrong microbes can drive compulsive behavior, and how toxic foods, glyphosate, and antibiotics have turned our guts into neurological war zones. Most shocking of all? Microbes may not just influence addiction—they may cause it. What You’ll Learn in This Episode: • How your gut microbiome can hijack your brain and influence your thoughts and behavior • Why certain microbes may actually cause addiction, obesity, and depression • How antibiotics, glyphosate, and processed foods are turning your gut into a desert • How to rebuild your gut ecosystem using postbiotics, fermented foods, and precision inputs • Why food cravings might be microbial mind control—and what to do about it • What the latest science reveals about the gut-brain axis, neurotransmitters, and neuroinflammation Sponsors: -Sunlighten | Go to https://www.sunlighten.com/dave/ and enter code DAVE at checkout to save up to $1,400. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dr. Gundry’s Instagram – https://www.instagram.com/drstevengundry/?hl=en • Dr. Gundry’s Website: https://drgundry.com/ • Dr. Gundry’s New Book The Gut-Brain Paradox: https://www.barnesandnoble.com/w/the-gut-brain-paradox-steven-r-gundry-md/1146019686?ean=9780062911803 • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:01 — Intro • 03:55 — The Gut-Brain Connection • 04:45 — Microbiome Communication and Control • 08:19 — The Role of Fungi and Plants • 11:29 — Microbiome Diversity and Health • 19:05 — Addictive Microbiome and Behavior • 28:17 — Antibiotics and Gut Health • 30:49 — Listener Concerns and Gut Health • 31:02 — Whale Watching and Climate Change • 32:58 — Understanding SIBO and Bacterial Migration • 34:02 — The Role of Soluble Fiber and Fermented Foods • 36:12 — Complexity of Gut Microbiome • 36:49 — Restoring Ecosystems and Gut Health • 38:23 — Precision Microbiome Manipulation • 41:31 — Calcium Formation and Gut Bacteria • 43:56 — Oxalates vs. Lectins Debate • 46:04 — Whole Foods and Glyphosate Concerns • 51:47 — Dopamine Levels and Gut Health • 54:59 — Conclusion and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    54 m
  • Longevity Scientists Discover a Breakthrough Peptide That Reverses Hair Loss | Carolina Reis Oliveira : 1269
    Apr 11 2025
    If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that? In this episode, Dave Asprey uncovers the cellular biology of hair thinning with longevity researcher Carolina Reis Oliveira. You’ll learn how senescent cells (aka zombie cells) hijack your scalp, disrupt follicle function, and silently accelerate hair loss—and how a breakthrough peptide might stop it cold. Carolina reveals brand-new clinical research on OS-01, a molecule shown to increase hair density by 40% in just 6 months. But this isn’t a product pitch—it’s a paradigm shift. Together, they explore the hidden drivers of hair aging, from hormone shifts and stress cascades to microbiome imbalances and inflammation, plus the real science behind what can actually regrow hair. What You’ll Learn in This Episode: • How “zombie cells” (senescent cells) sabotage your hair from the inside out • The science behind the OS-01 peptide and how it reverses visible hair thinning • Why thinning hair isn’t just genetic—and what else is driving it • How stress, hormones, and aging collide to trigger follicle dysfunction • What your scalp microbiome has to do with regrowth and hair density • How to stack red light, peptides, and topicals for real, measurable results ***Visit oneskin.co/DAVE and use code DAVE for and additional 15% off.*** Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OneSkin Instagram – https://www.instagram.com/oneskin.co/ • OneSkin Website: https://www.oneskin.co/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 01:52 — Intro • 02:59 — Is Aging Optional for Your Scalp? • 04:03 — Understanding Scalp and Hair Aging • 05:06 — The Role of Senescent Cells in Hair Loss • 07:25 — Hormonal Influences on Hair Health • 16:10 — Peptide Solutions for Hair Thinning • 18:05 — Clinical Studies and Results • 20:29 — Future of Hair Loss Treatments • 30:16 — Nutritional and Lifestyle Factors • 36:40 — Addressing Senescent Cells and Hair Growth • 37:29 — Minoxidil: Oral vs. Topical Use • 39:32 — Personal Experience with Hair Products • 40:25 — Combining Therapies for Hair Growth • 46:06 — Nutritional Factors in Hair Health • 52:20 — Sun Exposure and Hair Health • 56:40 — Coffee and Hair Growth • 01:00:01 — Launching the New Hair Product See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h
  • Identity Hacker: How to Completely Change Your Personality at ANY Age | Olga Khazan : 1268
    Apr 10 2025
    What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixed—they’re fluid. And more importantly: they’re up for grabs. Joining him is award-winning journalist from The Atlantic, Olga Khazan, author of Me, But Better, who spent years hacking her own mind—transforming high neuroticism, social avoidance, and chronic self-criticism into calm, confidence, and connection. Her personal experiment in identity rewiring became a roadmap for anyone who wants to feel different… and live differently. You’ll uncover the hidden mechanisms behind neuroticism, reactivity, and emotional spirals—and how to override them with real-time upgrades. What You’ll Learn in This Episode: • Why your personality is a program—and how to recode it • What daily behaviors scientifically rewire anxiety, anger, and reactivity • The surprising link between identity, inflammation, and your gut • Why gratitude isn’t soft—it’s neurological jiu-jitsu • How to know if it’s your biology or your story running the show • Whether pills, psychedelics, or sleep do more to shift who you are • What to do when your inner critic won’t shut up • And how to stop being the person you never meant to become SPONSORS -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE. -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Resources: • Olga’s New Book – Me, But Better: https://www.amazon.com/Me-But-Better-Science-Personality/dp/1668012545 • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Olga's Instagram – https://www.instagram.com/olganator/?hl=en • Olga’s Website: https://olgakhazan.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:52 — Intro • 2:16 — Personality Changes and Neuroticism • 5:38 — Postpartum Personality Shifts • 10:21 — Gratitude and Cultural Beliefs • 18:13 — Anger Management and Empathy • 32:58 — Personality Traits and Boundaries • 35:46 — The Importance of Strong Boundaries • 36:07 — Personality Change as Self-Improvement • 37:22 — The Role of Medication in Personality Change • 39:18 — Brain-Body Connection and Mental Health • 43:26 — Impact of Sleep and Nutrition on Personality • 44:23 — Nicotine and Other Substances • 45:41 — Therapy and Personality Change • 46:43 — Changing Personality Through Behavior • 1:01:25 — The Role of Relationships in Personality Development • 1:04:49 — Challenges and Methods in Personality Change • 1:08:38 — The Power of Improv in Personality Change • 1:10:17 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 h y 6 m
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