• Analyzing Nanoviricides' Shift to RSV Treatments with Proactive Healthcare Analyst Dr. John Savin
    May 21 2024
    Proactive Healthcare Analyst Dr John Savin joined Steve Darling to delved into the recent strategic developments at NanoViricides, shedding light on the company's transition from COVID-19 to respiratory syncytial virus (RSV) treatments. Initially known for its polymer antiviral agent targeting COVID-19, NanoViricides garnered attention with clinical trials conducted in India during the height of the pandemic. However, with the decline of COVID-19 cases, the company has shifted its focus towards tackling RSV, a prevalent lung infection. Dr. Savin highlighted the significance of this pivot, considering RSV's substantial market potential and the limited availability of acute therapies. RSV, currently addressed primarily through vaccines and antibody products, presents a lucrative market valued at $3 billion annually, with forecasts suggesting a potential surge to $8 billion within the next decade. Unlike vaccines requiring pre-infection administration, acute therapies for RSV are scarce, creating a ripe opportunity for Nanoviricides to make a meaningful impact. Dr. Savin outlined NanoViricides' pathway in the RSV space, which entails seeking regulatory approval in the United States. Key milestones in this journey include engaging in discussions with the FDA and submitting regulatory dossiers, a process expected to extend into the spring of the following year. Despite facing financial constraints, with only $3.2 million available, Nanoviricides remains undeterred in its pursuit. The company plans to leverage existing loan facilities, explore market opportunities, and even consider mortgaging assets if necessary to fund its anticipated clinical trials. Dr. Savin estimated the trial cost to be at least $5 million USD, earmarked for the 2026 financial year. Encouraging preclinical data bolster NanoViricides' confidence in the potential success of its upcoming trials. Dr. Savin underscored the importance of focusing on a single indication to accumulate substantial clinical data and establish credibility within the medical community and among investors. Overall, NanoViricides' strategic shift towards RSV treatments signals a calculated move to capitalize on a burgeoning market opportunity, leveraging its expertise and resources to address an unmet medical need and potentially revolutionize the landscape of acute viral infection therapeutics. #proactiveinvestors #nanoviricidesinc #nyseamerican #nnvc #biotec #ClinicalTrials #FDAApproval #NanoVariousSides #COVID19 #VirusTreatment #PolymerAntiviral #USRegulatory #VaccineMarket #Biotechnology #HealthcareFunding #MedicalResearch #PreclinicalData #InfectionTreatment #BiotechFunding #USHealthcare #AntiviralResearch #HealthInnovation #RSVTreatment #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    4 mins
  • Flynn Gold discovers significant high-grade gold at Link Zone
    May 21 2024
    Flynn Gold Ltd (ASX:FG1) CEO Neil Marston joins Proactive’s Jonathan Jackson to discuss the discovery of a new high-grade mineralisation zone at Link Zone prospect within the Golden Ridge Project in Northeast Tasmania. A recent field mapping and sampling campaign at the historic Golden Ridge adit revealed high-grade veins, with underground grab sampling recording assays of 64.4 g/t, 37.6 g/t and 15.9 g/t gold. These findings have driven the company’s share price up by as much as 48.2%, reaching $0.04. The Link Zone prospect is strategically located between the Trafalgar and Brilliant prospects along the Golden Ridge granodiorite contact, hosting a corridor of high-grade gold mineralisation with a potential strike length of 2.5 kilometres and vertical extent of at least 500 metres. Previous diamond drilling at Trafalgar and Brilliant yielded outstanding results, with multiple intersections exceeding 100 g/t of gold at Trafalgar. This is being further investigated through an active diamond drilling campaign. The new mineralised veins at Link Zone present fresh drill targets, potentially extending the existing gold system. Currently, Phase 3 diamond drilling at Trafalgar is in progress, with samples from the first hole under laboratory analysis. The drill program aims to infill test high-grade zones from previous programs and explore extensions to known mineralisation along the gold-bearing granodiorite-metasediment contact, now extending over 9 kilometres. Marston, stated that the Link Zone results enhance their confidence in the extensive, high-grade gold system at Golden Ridge, with ongoing exploration efforts aimed at identifying additional drilling targets. #proactiveinvestors #FlynnGold #ASX #GoldenRidge #HighGradeGold #LinkZone #GoldExploration #ASX #Mineralisation #GoldMining #TasmaniaGold #StockMarket #GoldAssays #DiamondDrilling #GoldSystem #TrafalgarProspect #BrilliantProspect #Granodiorite #Metasediment #MiningNews #GoldShares #ResourceInvesting#stockmarketnews
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    6 mins
  • Prescient Therapeutics PTX-100 shows promising results in Phase 1b study
    May 21 2024
    Prescient Therapeutics Ltd (ASX:PTX, OTC:PSTTF) CEO and managing director Steven Yatomi-Clarke sits down with Jonathan Jackson in the Proactive studio ahead of a presentation of the results of its PTX-100 Phase 1b study at the 15th Annual T-Cell Lymphoma Forum (TCLF) in California from June 6 to 8. The Phase 1b study targeted patients with relapsed and refractory T-cell lymphomas (r/r TCLs) and successfully met its primary objectives of demonstrating safety and determining pharmacokinetics and pharmacodynamics. Additionally, the study showed a promising preliminary efficacy with a 45% overall response rate, where five out of 11 evaluable patients responded positively to the treatment. T-cell lymphomas are a rare type of non-Hodgkin lymphoma, classified as an orphan disease with about 30,000 cases. PTX-100 has received Orphan Drug Designation from the US FDA, highlighting the need for more effective treatments for TCLs, particularly for relapsed and refractory cases. The T-Cell Lymphoma Forum is a specialised conference focused on advancements in TCL treatment, bringing together clinicians, scientists and industry professionals. Yatomi-Clarke, emphasised the importance of this platform for sharing critical research and the significance of PTX-100 in addressing an unmet medical need. The company plans to advance to a Phase 2 trial in r/r TCL, expected to commence in Q3 2024. #ProactiveInvestors #PrescientTherapeutics #ASX #OTC #PTX100 #TCLF #TCellLymphoma #OncologyResearch #ClinicalTrial #Phase1bStudy #OrphanDrug #USFDA #Pharmacokinetics #Pharmacodynamics #CancerTreatment #MedicalResearch #Hematology #RareDisease #DrugDevelopment #HealthcareInnovation #StevenYatomiClarke #MilesPrince #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    7 mins
  • Maximus Resources and KOMIR partner to advance Lefroy Lithium Project
    May 21 2024
    Maximus Resources Ltd (ASX:MXR, OTC:MXRRF) managing director Tim Wither joins Proactive’s Jonathan Jackson to discuss Australian Foreign Investment Review Board (FIRB) approval to proceed with a joint venture with Korea Mine Rehabilitation and Mineral Resources Corporation (KOMIR) in which KOMIR will invest US$3 million (A$4.5 million) to earn a 30% interest in Maximus' Lefroy Lithium Project in Western Australia. The Lefroy Project is in the Eastern Goldfields lithium corridor and includes mining tenements in the lithium-caesium-tantalum (LCT) province, near Mt Marion and Bald Hill lithium mines. Maximus holds a portfolio of gold, lithium and nickel projects in the Kambalda region, with more than 335,000 ounces of gold resources. Wither highlighted the FIRB approval as a key milestone, enabling the company to advance the Lefroy Project with KOMIR’s investment. The company utilised a US$200,000 non-refundable deposit during the FIRB review to enhance geological understanding and identify promising targets at Kandui, Yilmia, and Landor through soil geochemistry mapping and a 3,000-metre RC drill program. In November 2023, Maximus intersected high-grade spodumene-bearing pegmatites at Kandui, which will be the focus of the upcoming drill program. #ProactiveInvestors #MaximusResources #ASX #KOMIR #LefroyLithiumProject #LithiumExploration #MiningInvestment #GoldfieldsLithium #Spodumene #Geochemistry #DrillProgram #MiningTenements #LithiumCorridor #LithiumMining #GoldExploration #NickelExploration #KambaldaRegion #MineralResources #MtMarion #BaldHill #ASX #OTC #MiningApproval #LithiumProduction #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    6 mins
  • Accelerate Resources begins maiden drilling at Prinsep Lithium Project
    May 21 2024
    Accelerate Resources Ltd (ASX:AX8) CEO Luke Meter sits down with Proactive’s Jonathan Jackson to discuss the company’s first drilling campaign at the Prinsep Lithium Project near Karratha in the West Pilbara region of Western Australia. Drilling follows surface sampling indicating lithium mineralisation up to 1.68% Li2O. The maiden program will involve 48 reverse circulation (RC) drill holes totalling 3,500 metres, targeting pegmatite discoveries over a 1,500-metre strike and widths up to 60 metres. The drilling is expected to be completed by the end of June, with samples sent in batches for assaying, which will have a turnaround time of about six weeks. According to Meter, this marks a significant milestone for the company as it targets lithium mineralisation down dip of outcropping mineralisation and new pegmatite sets hidden by cover. The program focuses on the northern pegmatite system, where previous mapping and rock chip sampling have confirmed lithium presence. Initial drill holes will be completed on fenced 80-metre spaced lines, targeting surface mineralisation followed by deeper increments of approximately 50 and 100 metres below the surface. A small drill hole orientation program will also be conducted along the southern pegmatite trend to assist with planning the second phase of drilling. Prinsep is 15 kilometres south of Karratha and 35 kilometres west of the SH Mining Andover Lithium Project. It is part of the larger Karratha Lithium Project portfolio, which spans about 85 square kilometres within the Karratha-Roebourne hard-rock lithium belt. Two sub-parallel pegmatite zones have been defined, each extending over 1,800 metres with widths up to 60 metres and rock chip sample assays up to 2.06% Li2O. #ProactiveInvestors #AccelerateResources #ASX #LithiumProject, #PrinsepProject, #KarrathaLithium, #WestPilbara, #LithiumExploration, #DrillingCampaign, #LithiumMineralisation, #RCDrilling, #MiningNews, #LithiumBelt, #Karratha, #AustraliaMining, #ResourceDevelopment, #ExplorationResults, #MineralExploration, #LithiumBatteries, #MiningIndustry, #ASXNews, #BatteryMetals #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    4 mins
  • Immunic CMO discusses role of clinical trials in biotech development for Clinical Trials Day
    May 20 2024
    Immunic Inc (NASDAQ:IMUX) chief medical officer Dr Andreas Muehler discusses the importance of clinical trials in the biotech industry to mark Clinical Trials Day on May 20. Dr Muehler noted that Immunic focuses on translating research ideas into clinical trials to demonstrate clinical proof of concept as well as safety and efficacy of a drug candidate. He explained the stages of clinical development, from preclinical trials to late-stage phase 3 trials and commercialization. Preclinical trials involve testing in animals and cell cultures to ensure safety before human testing begins. Phase 1 trials assess safety and pharmacokinetics, while phase 2 trials determine the appropriate dosage. Phase 3 trials involve large-scale testing to obtain statistically significant outcomes for regulatory approval. Dr Muehler emphasized the importance of continuous clinical development, even after drug approval, to monitor for rare side effects and test in different populations. Clinical trials at Immunic are organized by medical and clinical operations teams and executed with the help of contract research organisations (CROs) to manage the trials across various countries. Dr Muehler highlighted the challenges in clinical trials, such as patient recruitment and the need for effective planning and communication with key opinion leaders and investigators. He shared that staying in close contact with investigators through meetings, site visits, and newsletters helps in efficient trial execution and patient enrolment. Immunic's approach has been successful in rapidly enrolling patients for trials, particularly in multiple sclerosis studies, he added. #ImmunicInc, #ClinicalTrials, #Biotech, #DrugDevelopment, #ClinicalResearch, #PhaseOne, #PhaseTwo, #PhaseThree, #Preclinical, #DrugApproval, #PatientRecruitment, #CRO, #ClinicalOperations, #MultipleSclerosis, #MedicalResearch, #Pharmacokinetics, #ClinicalProof, #BiotechIndustry, #Healthcare, #InnovativeMedicine #ProactiveInvestors #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    11 mins
  • Alligator Energy launches drilling at Big Lake Uranium Project
    May 20 2024
    Alligator Energy Ltd (ASX:AGE, OTC:ALGEF) CEO Greg Hall is back in the Proactive studio after the company began drilling at the Big Lake Uranium Project in South Australia’s Cooper Basin. Wallis Drilling has been contracted to complete up to 40 aircore holes on cross-sectional lines, with holes spaced 50-200 metres apart and averaging 150 metres in depth. AGE’s inaugural program aims to pinpoint northern extensions to the Namba, Eyre and Winton sedimentary formations, which also host prominent Beverley, Four Mile and Honeymoon ISR uranium operations in South Australia. Historical drilling around 16 years ago indicated uranium presence in thin bands and Hall is confident that the project shares characteristics with other global hydrocarbon-related in-situ recovery (ISR) uranium fields. Speaking with Proactive’s Elisha Newell, Hall said he was pleased to get the program underway, thanking traditional landowners and stakeholders for their role in the campaign’s commencement. While it’s still early days, the MD believes the project shows potential to follow the Kazakhstan uranium-bearing basin model. Ultimately, results from the program — expected in August or September — will guide more targeted drilling efforts later in 2024 or early 2025. #ProactiveInvestors #AlligatorEnergy #ASX #BigLakeUranium #CooperBasin #UraniumExploration #StratigraphicDrilling #NambaFormation #EyreFormation #WintonFormation #InSituRecovery #ISRMining #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    7 mins
  • Intra Energy Corporation discovers high-grade gold at Maggie Hays Hill
    May 20 2024
    Intra Energy Corporation Ltd (ASX:IEC) managing director Ben Dunn sits down with Proactive’s Jonathan Jackson to discuss the discovery of high-grade gold at the Maggie Hays Hill (MHH) Project in Western Australia’s Lake Johnston Greenstone Belt. Assay results from 11 rock chip samples collected in March and April averaged 2.56 g/t of gold, with the highest assay at 7.6 g/t. Three parallel quartz reefs, each more than 250 metres long, have been identified. IEC has also found significant gold and lithium targets through a soil sampling program. The northern anomaly spans 1,500 by 150 metres, with gold grades averaging 30 ppb, while a southern anomaly aligns with central quartz reefs, averaging 31 ppb. Dunn expressed satisfaction with the rapid progress of the exploration program, led by Todd Hibberd. The team is preparing to drill in mid-June 2024, pending the acquisition of necessary permits and heritage clearances. A heritage survey is set to begin on May 30 and drilling permits are awaiting approval from the Department of Mines, Industry Regulation, Energy and Safety (DMIRS). The MHH Project, 80% owned by IEC, is prospective for lithium, nickel and gold, and is located near the Maggie Hays and Emily Anne nickel mines. The region’s geological features and recent commercial activities highlight its potential for significant mineral discoveries. #ProactiveInvestors #IntraEnergyCorporation #ASX #MaggieHaysHill #GoldDiscovery #LakeJohnstonGreenstoneBelt #HighGradeGold #ExplorationProject #WesternAustralia #QuartzReefs #SoilSampling #LithiumTargets #DrillingProgram #MiningPermits #HeritageClearance #GeologicalSurvey #NickelMines #SpodumeneLithium #MineralExploration #MiningIndustry #CommercialActivities #RioTinto #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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    8 mins