-
Lifespan
- Why We Age – and Why We Don’t Have To
- Narrated by: Dr David A. Sinclair
- Length: 11 hrs and 55 mins
Failed to add items
Add to Cart failed.
Add to Wish List failed.
Remove from wishlist failed.
Adding to library failed
Follow podcast failed
Unfollow podcast failed
Get 2 free audiobooks during trial.
Buy for $26.13
No default payment method selected.
We are sorry. We are not allowed to sell this product with the selected payment method
Publisher's summary
In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help listeners live younger, longer.
For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable.
But what if everything you think you know about ageing is wrong?
What if ageing is a disease? And that disease is curable.
In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.
But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Listeners will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more.
Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
Critic reviews
‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’ – Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author
‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’ – Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It!
‘In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply.’ – Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author
Related to this topic
-
Complexity
- The Emerging Science at the Edge of Order and Chaos
- By: M. Mitchell Waldrop
- Narrated by: Mikael Naramore
- Length: 17 hrs and 8 mins
- Unabridged
-
Overall
-
Performance
-
Story
In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell--and what the origin of life some four billion years ago can tell us about the process of technological innovation today.
-
-
You won't learn anything you didn't know
- By Dennis E. Alwine on 12-26-20
-
Brain Energy
- A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More
- By: Christopher M. Palmer MD
- Narrated by: Christopher M. Palmer MD
- Length: 12 hrs and 18 mins
- Unabridged
-
Overall
-
Performance
-
Story
We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.
-
-
Arguing brain health theory to medical profession
- By Maya H Saric on 03-10-23
-
The Selfish Gene
- By: Richard Dawkins
- Narrated by: Richard Dawkins, Lalla Ward
- Length: 16 hrs and 12 mins
- Unabridged
-
Overall
-
Performance
-
Story
Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.
-
-
Better than print!
- By J. D. May on 07-31-12
By: Richard Dawkins
-
Napoleon's Hemorrhoids…And Other Small Events That Changed History
- By: Phil Mason
- Narrated by: LJ Ganser
- Length: 8 hrs and 13 mins
- Unabridged
-
Overall
-
Performance
-
Story
Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.
-
-
They just throw the facts too fast
- By Concerned_llama on 12-11-20
By: Phil Mason
-
How the Earth Works
- By: Michael E. Wysession, The Great Courses
- Narrated by: Michael E. Wysession
- Length: 24 hrs and 31 mins
- Original Recording
-
Overall
-
Performance
-
Story
How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.
-
-
Excellent course
- By Doug B. on 05-23-19
By: Michael E. Wysession, and others
-
Buried in the Sky
- The Extraordinary Story of the Sherpa Climbers on K2's Deadliest Day
- By: Peter Zuckerman, Amanda Padoan
- Narrated by: David Doersch
- Length: 7 hrs and 12 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Edmund Hillary first conquered Mt. Everest, Sherpa Tenzing Norgay was at his side. Indeed, for as long as Westerners have been climbing the Himalaya, Sherpas have been the unsung heroes in the background. In August 2008, when eleven climbers lost their lives on K2, the world’s most dangerous peak, two Sherpas survived. They had emerged from poverty and political turmoil to become two of the most skillful mountaineers on earth. Based on unprecedented access and interviews, Buried in the Sky reveals their astonishing story for the first time.
-
-
Sherpas, The True Unsung Heroes
- By Kathy in CA on 07-26-15
By: Peter Zuckerman, and others
-
Complexity
- The Emerging Science at the Edge of Order and Chaos
- By: M. Mitchell Waldrop
- Narrated by: Mikael Naramore
- Length: 17 hrs and 8 mins
- Unabridged
-
Overall
-
Performance
-
Story
In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell--and what the origin of life some four billion years ago can tell us about the process of technological innovation today.
-
-
You won't learn anything you didn't know
- By Dennis E. Alwine on 12-26-20
-
Brain Energy
- A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More
- By: Christopher M. Palmer MD
- Narrated by: Christopher M. Palmer MD
- Length: 12 hrs and 18 mins
- Unabridged
-
Overall
-
Performance
-
Story
We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.
-
-
Arguing brain health theory to medical profession
- By Maya H Saric on 03-10-23
-
The Selfish Gene
- By: Richard Dawkins
- Narrated by: Richard Dawkins, Lalla Ward
- Length: 16 hrs and 12 mins
- Unabridged
-
Overall
-
Performance
-
Story
Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.
-
-
Better than print!
- By J. D. May on 07-31-12
By: Richard Dawkins
-
Napoleon's Hemorrhoids…And Other Small Events That Changed History
- By: Phil Mason
- Narrated by: LJ Ganser
- Length: 8 hrs and 13 mins
- Unabridged
-
Overall
-
Performance
-
Story
Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.
-
-
They just throw the facts too fast
- By Concerned_llama on 12-11-20
By: Phil Mason
-
How the Earth Works
- By: Michael E. Wysession, The Great Courses
- Narrated by: Michael E. Wysession
- Length: 24 hrs and 31 mins
- Original Recording
-
Overall
-
Performance
-
Story
How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.
-
-
Excellent course
- By Doug B. on 05-23-19
By: Michael E. Wysession, and others
-
Buried in the Sky
- The Extraordinary Story of the Sherpa Climbers on K2's Deadliest Day
- By: Peter Zuckerman, Amanda Padoan
- Narrated by: David Doersch
- Length: 7 hrs and 12 mins
- Unabridged
-
Overall
-
Performance
-
Story
When Edmund Hillary first conquered Mt. Everest, Sherpa Tenzing Norgay was at his side. Indeed, for as long as Westerners have been climbing the Himalaya, Sherpas have been the unsung heroes in the background. In August 2008, when eleven climbers lost their lives on K2, the world’s most dangerous peak, two Sherpas survived. They had emerged from poverty and political turmoil to become two of the most skillful mountaineers on earth. Based on unprecedented access and interviews, Buried in the Sky reveals their astonishing story for the first time.
-
-
Sherpas, The True Unsung Heroes
- By Kathy in CA on 07-26-15
By: Peter Zuckerman, and others
-
Chemistry and Our Universe
- How It All Works
- By: Ron B. Davis, The Great Courses
- Narrated by: Ron B. Davis
- Length: 30 hrs and 6 mins
- Original Recording
-
Overall
-
Performance
-
Story
Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.
-
-
Great Professor, Hard to Follow.
- By Jen on 05-14-19
By: Ron B. Davis, and others
-
Letters from an Astrophysicist
- By: Neil deGrasse Tyson
- Narrated by: Neil deGrasse Tyson, Vikas Adam, Piper Goodeve, and others
- Length: 5 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.
-
-
Dear Neil...
- By Tina G. on 10-14-19
-
Ranger Confidential
- Living, Working, and Dying in the National Parks
- By: Andrea Lankford
- Narrated by: Julia Motyka
- Length: 9 hrs and 28 mins
- Unabridged
-
Overall
-
Performance
-
Story
The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.
-
-
Depressing from Cover to Cover
- By Drew (@drewsant) on 04-13-15
By: Andrea Lankford
-
Welcome to the Universe
- An Astrophysical Tour
- By: Michael A. Strauss, J. Richard Gott, Neil deGrasse Tyson
- Narrated by: Michael Butler Murray
- Length: 17 hrs and 53 mins
- Unabridged
-
Overall
-
Performance
-
Story
Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.
-
-
All About What We Know About the Universe - ALL
- By J.B. on 02-17-17
By: Michael A. Strauss, and others
-
Naked Statistics
- Stripping the Dread from the Data
- By: Charles Wheelan
- Narrated by: Jonathan Davis
- Length: 10 hrs and 48 mins
- Unabridged
-
Overall
-
Performance
-
Story
From batting averages and political polls to game shows and medical research, the real-world application of statistics continues to grow by leaps and bounds. How can we catch schools that cheat on standardized tests? How does Netflix know which movies you'll like? What is causing the rising incidence of autism? As best-selling author Charles Wheelan shows us in Naked Statistics, the right data and a few well-chosen statistical tools can help us answer these questions and more.
-
-
Starts well then becomes non-Audible
- By Michael on 09-07-13
By: Charles Wheelan
-
Mycophilia
- Revelations From the Weird World of Mushrooms
- By: Eugenia Bone
- Narrated by: Aimee Jolson
- Length: 11 hrs and 2 mins
- Unabridged
-
Overall
-
Performance
-
Story
In Mycophilia, accomplished food writer and cookbook author Eugenia Bone examines the role of fungi as exotic delicacy, curative, poison, and hallucinogen, and ultimately discovers that a greater understanding of fungi is key to facing many challenges of the 21st century.
-
-
Absolutely awful, insufferable, racist author
- By Rs 🦇 on 11-25-19
By: Eugenia Bone
What listeners say about Lifespan
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
-
Overall
-
Performance
-
Story
- Amazon Customer
- 11-12-19
Excellent! Loved the listen.
I would highly recommend this this audio book. I really enjoyed listening to all the latest research and understanding why things work the way they do. This book could potentially have a major impact on your life.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
1 person found this helpful
-
Overall
-
Performance
-
Story
- Setken
- 08-26-20
Human longevity science made understandable
Dr. Sinclair discsses his research and successes with longevity science, and is not afraid to give his personal opinions on the subject either - rare for scientists usually. It is in fact this human-ness that gives the book its charm, and likely why he'll be successful in sorting aging out once and for all. I believe that good people with good intentions ultimately reach their aims. I am hoping and praying that he does, for all of us.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Jim
- 01-07-20
Will change your life, if you let it.
A book that so many around the world should read, if only a small amount of what is in this book it's taken on by everyone around the world it will be a big step forward. Great insights and food for thought.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
1 person found this helpful
-
Overall
-
Performance
-
Story
- Anonymous User
- 01-18-23
Excellent Book
excellent book, really enjoyed it and very informative .Also well performed by author . well done
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- beinloveart
- 12-20-19
Buy the paperback for all the people you love
It’s a beautiful book to listen to; and I can see that David Sinclair will be written in the history books as the man who fought to convert 21st century medicine scholars into focusing on ageing as a disease, rather than wasting so much of each countries taxed funds on individual diseases. He makes me so proud to be an Australian. Thanks David and family.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
4 people found this helpful
-
Overall
-
Performance
-
Story
- Dinesh Senan
- 12-24-22
Eye Opening Work
This book is a MUST READ for all who love life. That ageing is a disease represents a quantum paradigm shift that will be met with much typical human mental inertia and resistance. I congratulate the author for his professional persistence and thank him for his ongoing efforts.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- David
- 07-03-22
amazing audio well synchronized
Narrator was amazing from the begnning to the end, highly recommended.
I loved it
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Stephen
- 10-12-20
Life-changing
The knowledge shared in this book really is life-changing. If, and that ‘if’ is becoming stronger every day, we will live to much older age with vibrancy and our wits, we have to reconsider everything, from the way we look after ourselves to the way we impact the world.
This book was very well-written, without hyperbole and embracing critical analysis. Dr Sinclair did a fabulous job of delivering the audio version as well.
This is a strong recommendation.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
1 person found this helpful
-
Overall
-
Performance
-
Story
- Rezma
- 02-18-20
Insightful and useful read
Must read for anyone keen to learn and apply a little more to their well being. The cutting edge information on how to optimise your health is invaluable! Can't thank Dr Sinclair enough for his efforts and generosity for sharing information.
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!
-
Overall
-
Performance
-
Story
- Yoav
- 09-26-19
Informative and eye opening.
excellent book! comprehensive, fascinating, up to date information. begins with the science, but than sidetracks a lot to discuss philosophy and ethics (a bit too much).
Something went wrong. Please try again in a few minutes.
You voted on this review!
You reported this review!