In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Mariah Gannessa, founder of Four Visions, a plant medicine platform rooted in sacred reciprocity and indigenous partnership.

Find full show notes and links here:
https://thethirdwave.co/podcast/episode-317/?ref=278

Mariah shares her decade-long apprenticeship with the Inga people of Colombia and her journey creating Four Visions as a reverent bridge between Amazonian healing traditions and modern seekers.

The conversation explores the Four Visions of the Yahé tradition, the nuances of cultural appropriation vs. cultural exchange, and the responsibilities of Western entrepreneurs engaging with indigenous medicines. Mariah also discusses how Four Visions reinvests in indigenous communities and why the concept of sacred reciprocity is central to her mission.

Join Paul F. Austin and Mariah Gannessa on August 21st at 10am PT / 1pm ET for Hapé 101 for Practitioners, Coaches & Guides, a free live webinar hosted through the Psychedelic Coaching Institute. Whether you're new to hapé or looking to deepen your practice, you'll gain practical, respectful guidance on working with this sacred Amazonian snuff—personally and professionally.

Mariah Gannessa has spent the last decade immersed in the healing cultures of the Amazon and has dedicated her life’s work to the plants and indigenous peoples of the rainforest. Her healing journey during her decade-long apprenticeship in study and service with the Inga tribe of Putumayo was a catalyst for her evolution as an entrepreneur, philanthropist and musician.
Mariah acts as a bridge in the sharing of plant medicines with the world in order to support humanity’s healing. She is the founder of Four Visions, a global leader in supporting indigenous communities through direct commerce partnerships, donations, and sponsoring charitable initiatives. In partnership with her teacher, world-renowned healer and Ingano Botanist, Taita Juanito, she founded MAGIC Fund, spearheading projects to preserve the Amazonian peoples, their cultures, and lands. Her work in service is fully inspired by a vision to leave a legacy of a better Earth for future generations.

Highlights:

• How the Four Visions of Yagé shape healing
• Redefining sacred reciprocity in a globalized world
• A Western entrepreneur’s path through plant medicine apprenticeship
• Why cultural exchange is not always appropriation
• The role of reverence in spiritual entrepreneurship
• Bridging Amazonian wisdom with Western healing needs
• Building a mission-driven e-commerce platform
• Plant allies for the heart, grief, and dreaming
• Remembering ancestral wisdom in a disoriented world
• The medicine path as both business and spiritual devotion

Episode Links:

• Four Visions
• MAGIC Fund
• Hapé 101 for Practitioners, Coaches & Guides

Episode Sponsors:

• Psychedelic Coacing Institute's Intensive for Psychedelic Professionals in Costa Rica - a transformative retreat for personal and professional growth.

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

In this episode of The Psychedelic Podcast, host Paul F. Austin welcomes cultural historian and acclaimed author Mike Jay.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-316/?ref=278

Together they explore the untold history of nitrous oxide, psychedelic experimentation in the Romantic era, and the deeper cultural and philosophical roots of psychedelic science.

Mike shares insights from his latest book, Free Radicals, highlighting how figures like Humphry Davy and William James helped shape psychedelic thought long before the 1960s. The conversation weaves through ancient San Pedro rituals, colonial attempts to suppress peyote use, and the divergent paths of modern psychedelic medicine.

From poetic self-experimentation to medicalized models, Mike unpacks the historical tensions between grassroots healing and institutional control—and what this means for the future of psychedelic culture.

Mike Jay is a British author and cultural historian who has written widely on the history of drugs, consciousness, and medical science. His books include Mescaline: A Global History of the First Psychedelic, Psychonauts: Drugs and the Making of the Modern Mind, and Free Radicals: How a Group of Romantic Experimenters Gave Birth to Psychedelic Science. Mike contributes regularly to The London Review of Books, The New York Review of Books, and The Wall Street Journal.

Highlights:

• How early scientists used nitrous oxide for inner exploration
• Romantic poets as the original psychedelic self-experimenters
• Parallels between Humphry Davy and Alexander Shulgin
• What William James learned from nitrous, not mescaline
• Colonial suppression of peyote and indigenous resilience
• The enduring symbolism of San Pedro in Andean ritual
• How the counterculture reinterpreted Native practices
• Why modern psychedelic medicine may be repeating history
• The role of finance in shaping current therapy models
• Looking ahead: divergent futures of psychedelic healing

Episode links:

• Mike’s website
• Mike’s new book, Free Radicals
• Mescaline: A Global History of the First Psychedelic
• Psychonauts: Drugs and the Making of the Modern Mind
• Manvir Singh’s article in The Guardian
• “The Peyote Dance” by Antonin Artaud

Episode sponsors:

• Psychedelic Coacing Institute's Intensive for Psychedelic Professionals in Costa Rica - a transformative retreat for personal and professional growth.
• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

In this episode of The Psychedelic Podcast, host Paul F. Austin welcomes Brian Robertson—creator of Holacracy and founder of Ledgeway Sangha—for a thought-provoking conversation at the intersection of organizational design, spiritual community, and psychedelic practice.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-315/?ref=278

Best known for reimagining how companies structure authority through Holacracy, Brian now brings his systems-level insight into the realm of psychedelic spirituality. He shares the origin and mission of Ledgeway Sangha, a legal psychedelic church rooted in peer-to-peer healing, communal practice, and non-dogmatic love. Together, Paul and Brian explore how this innovative model bypasses conventional hierarchy, integrates softer entheogens like 2C-B and 6-APB, and builds a path toward legal protection for churches operating outside mainstream psychedelic frameworks.

Brian Robertson is best known for creating Holacracy, the most comprehensive framework in the world today for running self-managed companies using a decentralized power structure in lieu of a traditional management hierarchy. He’s founded and built many organizations over the past 30 years as an entrepreneur, including HolacracyOne, which helps companies use self-management to unleash creativity and empowered leadership, and the software company GlassFrog, which helps both traditional and self-managed companies drive organizational transparency, agility, and alignment to purpose.

To date, tens of thousands of companies in over 50 countries have embraced his pioneering methods and ideas, and his frequent public speaking seamlessly weaves between business, management, consciousness, and love. Brian is currently focused on building Ledgeway Sangha, an entheogenic church and community-building organization that’s harnessing psychedelics to help people release judgments and resistances into loving acceptance of all that is.

Highlights:

• From Holacracy to entheogenic spirituality
• Why Ledgeway Sangha has no doctrine or belief system
• Love as the norming force in community
• 2C-B and 6-APB as self-integrating medicines
• The case for subtle, sovereign psychedelic journeys
• A new model of psychedelic integration through consistency
• Why hierarchy undermines safe psychedelic containers
• Legal strategies under the Religious Freedom Restoration Act
• Creating a church for mystics, not priests
• Poetry, presence, and redefining spiritual transmission

Episode links:

• Ledgeway Sangha
• Holacracy
• Brian’s social media

Episode Sponsor:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout
• The Practitioner Certification Program by Third Wave’s Psychedelic Coaching Institute.

In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Vass Eliopoulos, co-founder of Longevity Health and a pioneer at the intersection of regenerative medicine, longevity science, and psychedelics.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-314/?ref=278

Dr. Vass shares his journey from emergency medicine to a proactive, prevention-based approach to health optimization for high performers.

Dr. Vass shares why today’s healthcare system fails to address the root causes of disease, the synergistic potential of psychedelics, stem cells, peptides, and hyperbaric oxygen therapy, and how chronic stress and inflammation underlie many modern conditions. He also outlines why psychedelics may be essential in reversing chronic inflammation and treating neurodegenerative diseases—and how prevention, not pathology, should guide the future of medicine.

Dr. Vassily Eliopoulos (Dr. Vass) is the Co-Founder and Chief Medical Officer of Longevity Health, a cutting-edge regenerative medicine clinic in Boulder, Colorado. A former ER physician and Peace Corps volunteer, Dr. Vass now helps high performers optimize their health through advanced diagnostics, regenerative therapies, and personalized plans. A black belt in Brazilian Jiu-Jitsu, avid climber, and kayaker, he brings deep experience in resilience and recovery to his clinical work.

Highlights:

• Why Vass left emergency medicine for longevity health
• COVID as a catalyst for self-directed wellness
• The failure of “sick care” to promote true health
• Psychedelics as first-line treatments for mental health
• Chronic stress, inflammation, and disease progression
• Synergies between psychedelics, stem cells, and peptides
• Prevention vs. pathology in modern medicine
• Neurodegeneration as chronic brain injury
• Future directions for regenerative and psychedelic therapies

Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute’s Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More.

Episode Links:

• Longevity Health Clinic
• Dr. Vassily’s Instagram

Episode Sponsor:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-313b/?ref=278

Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work.

If you’re a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights.

Highlights:

• How SSRIs blunt emotional range and alter awareness
• The neuroscience of serotonin and psychedelic receptors
• Serious risks of serotonin syndrome when mixing with SSRIs
• Ketamine’s role in tapering and unlocking neuroplasticity
• Practical tools to regulate the nervous system during SSRI withdrawal
• Recommended psilocybin strains for sensitive or anxious clients
• How long-term SSRI use may (or may not) affect psychedelic response
• Safety-first protocols for psychedelic integration
• The future of microdosing as a sustainable antidepressant approach

Episode Links:

• Dr. Dave Rabin’s Website
• Dr. Dave on Instagram
• Dr. Dave on LinkedIn
• Apollo Neuro
• Last week’s bonus episode with Dr. Robin Carhart-Harris: SSRIs vs. Psychedelics: From Blunting to Rebooting
• Episode 218 with Dr. Dave Rabin
• Episode 74 with Dr. Dave Rabin

Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute’s Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More.

Episode Sponsor:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Dr. Dan Engle—psychiatrist, neurologist, and integrative medicine pioneer—for a profound discussion on psychedelics, brain health, and healing.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-313/?ref=278

Dr. Dan shares his personal journey through traumatic brain injuries and recovery through both Western neurology and indigenous plant medicine traditions. They explore neuroplasticity vs. neurogenesis, ibogaine’s potential in brain injury recovery, and how belief, awe, and prayer shape healing outcomes. Dr. Dan also reflects on lessons psychiatry can learn from shamanic practice—highlighting the importance of service, community, and ceremony in catalyzing transformation.

Dr. Dan Engle is a psychiatrist whose work bridges regenerative medicine, psychedelic research, integrative spirituality, and peak performance. He is founder of Full Spectrum Medicine, a psychedelic integration platform, and Thank You Life, a nonprofit expanding access to psychedelic therapies. He is author of The Concussion Repair Manual and A Dose of Hope: A Story of MDMA-Assisted Psychotherapy.

Episode Highlights:

• Healing from traumatic brain injury
• Iboga vs. Ibogaine: Benefits and risks
• Neuroplasticity vs. neurogenesis explained
• The science of awe and belief in healing
• Shamanic lessons for modern psychiatry
• Critical learning periods after psychedelic sessions
• Psychedelics as clarogens and renewing agents
• The placebo effect and collective service
• Texas legislation and Ibogaine research
  
  

Episode Sponsors:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

In this episode of The Psychedelic Podcast, Paul F. Austin is joined by renowned neuroscientist Dr. Robin Carhart-Harris and microdosing policy advocate John Downs for a replay of a live event originally held on June 10th, Microdosing vs. SSRIs: What’s Happening in the Brain and Why It Matters.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-312b/?ref=278

Together, they explore the scientific distinctions between SSRIs and psychedelics, focusing on neuroimaging, brain entropy, emotional processing, and the REBUS model. Dr. Carhart-Harris shares key insights from landmark studies on psilocybin therapy and discusses the evidence (and limitations) around microdosing. John Downs closes the conversation with an update on the Microdosing Collective’s efforts to shift policy and expand access.

Robin Carhart-Harris, PhD is a neuropharmacologist, psychologist, and Ralph Metzner Distinguished Professor in Neurology and Psychiatry at the University of California, San Francisco. He leads the Psychedelics Division at UCSF’s Neuroscape and formerly founded and led the Centre for Psychedelic Research at Imperial College London.

John Downs is Executive Director of the Microdosing Collective, advocating for responsible policy reform and legal access to microdosing. With 25 years’ experience in sales, business development, and emerging markets, John helps individuals optimize mindset, performance, and purpose.

Episode Highlights:

• Why SSRIs blunt, while psychedelics reset emotional processing
• How psilocybin compares to antidepressants in clinical trials
• Brain entropy, plasticity, and the REBUS model explained
• The role of the default mode network in mental health
• Why microdosing research is still so limited
• Ketamine vs. psilocybin: differences in brain mechanisms
• Is serotonin syndrome a real microdosing risk?
• Can psychedelics reverse long-term SSRI effects?
• The Microdosing Collective’s mission for policy reform
• What Robin Carhart-Harris’ upcoming book will explore

Episode Links:

• Robin’s lab & upcoming book
• Microdosing Collective
• Join Dr. Robin Carhart-Harris at our Practitioner
  Intensive (November 5–10, Costa Rica)

Episode Sponsors:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout
• Psychedelic Coacing Isntitute's Intensive for Psychedelic Professionals in Costa Rica - a transformative retreat for personal and professional growth.

In this episode of The Psychedelic Podcast, host Paul F. Austin welcomes back J. Ashley T. Booth, LCSW, MS—a longtime friend, therapist, and psychedelic pioneer.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-312/?ref=278

Ashley shares her journey from community activism to clinical work with ketamine and MDMA, and her new illustrated guide to IFS, Quieting the Storm Within.

J. Ashley T. Booth, LCSW, MS has led the Southern California Psychedelic Society, served as MAPS trial coordinator for MDMA-assisted PTSD therapy, co-founded a ketamine clinic, and offers IFS, Hakomi, integration, and harm reduction training. Her illustrated picture book introduces IFS concepts through visuals and metaphor.

Highlights:

• Ashley’s 8‑year evolution from community to clinical work
• The origin and intent behind Quieting the Storm Within
• Clouds & sun: A visual metaphor for the internal landscape<
• How IFS helps reframe so-called “bad” behaviors with compassion
• Preparing for psychedelic journeys using parts work
• Somatic memory and frozen parts in the body
• Why low‑dose, psycholytic sessions create safer containers
• Clinical nuances: Ketamine vs. MDMA for specific inner parts
• The role of protector parts, consent, and titration in therapy
• Integrating survival strategies into resilience and wholeness

Episode Links:

• IFS and Beyond Website
• Ashley's book: Quieting the Storm Within (Amazon)

These show links may contain affiliate links. Third Wave receives a small percentage of the product price if you purchase through the above affiliate links.

Episode Sponsor:

• Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout