Kallos from Napal shared her expereince of LDN and how it helped her get her life back. She has UCTD, Vitiligo and PCOS

Kallos from Nepal shared her inspiring experience with Low-Dose Naltrexone (LDN) and how it has played a crucial role in helping her regain control of her life. Living with conditions such as Undifferentiated Connective Tissue Disease (UCTD), vitiligo, and Polycystic Ovary Syndrome (PCOS) had made daily life challenging for her.

Before starting LDN, Kallos struggled with various symptoms that significantly impacted her quality of life, including fatigue, skin issues, and hormonal imbalances. However, after discussing her options with her healthcare provider, she decided to try LDN as a part of her treatment plan.

Since incorporating LDN into her routine, she has noticed remarkable improvements in her overall well-being. Kallos feels more energetic, her skin condition has stabilized, and her symptoms of PCOS have become more manageable. She emphasizes how LDN has not only improved her physical health but has also positively affected her mental health, allowing her to engage more fully with her daily activities and reclaim her life.

Taran from the United States shares her journey with Ehlers-Danlos Syndrome (EDS) and Postural Orthostatic Tachycardia Syndrome (POTS), which began in 2015 when she suddenly passed out at work, becoming bedridden for six months. Despite being very active beforehand, she was left confused and distressed. After researching online and consulting with a cardiologist, Taran received diagnoses for POTS and EDS.

For several years, they underwent a trial-and-error approach to treatment. In September 2024, Taran's mother discovered low-dose naltrexone (LDN) as a potential treatment, leading Taran to a primary care physician specializing in EDS. Nervously, she started LDN at a low dose and experienced significant pain and fatigue relief within days. After finding their optimal dose at 4.5 mg, Taran described the medication as a life-changing experience.

Reflecting on her childhood, Taran recalls having eczema, random rashes, and food sensitivities, which went unnoticed due to their active lifestyle. Overall, she express gratitude for LDN and its impact on managing her symptoms.

Barb from Canada shares her 26-year journey with fibromyalgia, which began with chronic pain and a lengthy struggle for a diagnosis. Initially, she explored various treatments, including conventional medications like Oxycontin and alternative therapies, but found limited relief.

After learning about Low Dose Naltrexone (LDN) from the fibromyalgia community, she sought a doctor willing to prescribe it. After changing family doctors, Barb encountered a new physician who did not believe in fibromyalgia and refused to prescribe LDN. However, through the LDN Research Trust, she found a supportive doctor who offered remote consultations. Since starting LDN in April, Barb experienced remarkable improvements in energy and quality of life within three weeks, allowing her to engage in activities she had long avoided. Her transformation has surprised both her and her family, leading others to inquire about her treatment.

Deb from Australia shared her journey with rheumatoid arthritis, which she experienced for about four years before receiving a proper diagnosis. Initially, her GP attributed her chronic pain to other issues and suggested topical treatments. A physio at Nambbor General Hospital recognized her symptoms and referred her to a rheumatologist, who confirmed the diagnosis through blood tests and MRIs.

Deb was prescribed methotrexate and folic acid but sought an alternative due to her desire for a healthier lifestyle. She turned to low-dose naltrexone (LDN) upon her integrative GP's recommendation. After starting on LDN, she experienced nausea and dizziness but persevered. Eventually, she reached a dose of 4.5 mg and became completely pain-free, significantly improving her quality of life.

Deb expressed gratitude for LDN and noted feelings of euphoria and a boost in her overall health. Although her rheumatologist advised her to continue methotrexate for potential bone erosion, Deb felt fantastic on LDN and is looking forward to her next appointment. Additionally, she mentioned her background as a social worker, her previous burnout, and the possibility that autoimmune conditions run in her family.

Pamela from the United States shares her journey with hypermobile Ehlers-Danlos syndrome (hEDS) and mast cell activation syndrome (MCAS), detailing how Low Dose Naltrexone (LDN) transformed her quality of life.

She recalls being frequently ill as a child with chronic sore throats, fevers, and unexplained rashes, treated repeatedly with antibiotics, which left her with long-term side effects. In adulthood, she experienced worsening joint pain, migraines, back and neck problems, and multiple orthopedic challenges, especially after childbirth and through menopause.

After learning about LDN from Ehlers-Danlos support groups and a physiatrist, Pamela started treatment at 0.5 mg, later increasing to 3 mg. Initial side effects (constipation and nausea) subsided after two weeks, followed by significant improvements in pain levels, energy, and immune function—she hasn’t caught illnesses that previously plagued her.

She describes a clear decline when she was off LDN for 11 days, reinforcing its benefits. Pamela now enjoys more stability, less pain, better post-menopause symptoms, and greater day-to-day functionality.

Her advice: LDN is worth trying for chronic pain and autoimmune-related conditions, as it may improve both symptoms and general health with minimal side effects for most people.

Jannie, a 74-year-old from Canada, developed Complex Regional Pain Syndrome (CRPS) in 2016 after a severe foot injury and surgery. She began using Low Dose Naltrexone (LDN) after researching its benefits and, with her doctor’s support, became one of the first in her area to try it. LDN significantly reduced her nerve pain and allowed her to live an active life. After needing recent surgery to remove old hardware from her foot, her CRPS briefly returned when she had to stop LDN—but quickly improved once she restarted it. Janie encourages others with chronic pain to research, stay hopeful, and actively participate in their recovery.

Dr. Corey Rice, a former forensic scientist turned functional medicine physician, discussed his journey from solving crimes to treating patients by addressing root causes of illness. He sees adults of all ages, focusing on prevention and early detection through advanced blood work, gut microbiome analysis, autoimmune screening, and cancer liquid biopsies. His treatments begin with gut repair, nutrient repletion, and hormone balancing, sometimes using low-dose naltrexone (LDN) or peptides for immune modulation, regeneration, and anti-aging. He stresses personalized, proactive care and urges both doctors and patients to stay open-minded.

Shanika shares her long journey with autoimmune diseases, beginning with psoriasis in her youth. She highlights the challenges of managing symptoms and the struggle for a proper diagnosis. After years, she is diagnosed with sarcoidosis and finds relief through low dose naltrexone. As an advocate for LDN, she encourages others to explore this treatment and emphasizes the importance of self-advocacy in health management.