In this special episode, Joe sits down with health coach and SelfDecode Pro user Joline Schaaphok to walk through her personalized health insights using genetic data.

They explore everything from supplement recommendations and food sensitivities to overlooked risk factors like anemia and cardiovascular health. It’s a real-time example of how genetic reports, labs, and lifestyle data can work together to uncover actionable insights.

Whether you're a practitioner, a biohacker, or just curious about precision health, this live analysis offers a behind-the-scenes look at how to turn data into meaningful change.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Timestamps:

(00:00) Introduction to the Joe Cohen Show

(00:16) Meet Joline Schaaphok

(02:02) Diving into Joline's Genetic Results

(03:32) Macronutrient and Vitamin Recommendations

(04:41) Food Sensitivities and Allergies

(05:46) Health Overview Report: Genetic and Lifestyle Insights

(09:27) Supplement Recommendations and Customization

(23:29) Refining the Supplement List

(24:08) Optimizing the Daily Regimen

(25:29) Detailed Regimen Breakdown

(28:15) Advanced Filtering Techniques

(33:11) Addressing Anemia and Food Allergies

(39:17) Comprehensive Lab Testing

(40:50) Genetic Insights and Recommendations

(43:10) Final Thoughts and Next Steps

In this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider.

Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overall well-being. They dive into the specifics of how genetic insights can personalize treatment plans, leading to better, faster results.

Whether it's diagnosing mental health issues more accurately or managing physical health conditions like diabetes and inflammation, Sasha highlights the transformative impact of personalized medicine.

Tune in to understand why integrating genetic information into healthcare is not just an innovation but a necessity.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Timestamp:

(00:00) - Introduction to the Joe Cohen Show

(00:16) - Meet Sasha Powell

(00:56) - Using DNA for Personalized Health Solutions

(01:24) - Weight and Hormone Management Strategies

(03:11) - Blood Sugar Regulation and Diet Recommendations

(07:25) - Mental Health and Genetic Insights

(10:59) - The Role of Neurochemistry in Treatment Plans

(13:48) - Personalized Supplement Recommendations

(30:10) - The Importance of Methylation in Health

(34:03) - Utilizing Self Decode for Comprehensive Health Management

(38:31) - Optimizing Quality of Life

(39:06) - Longevity Screener Insights

(39:34) - Clinical Overview Report

(40:30) - Health Overview Report

(41:44) - Lab Data and Clinical Recommendations

(45:15) - Family Planning and Genetic Risks

(45:57) - Integrating Lab Tests and Genetic Data

(48:44) - Using SelfDecode in Clinical Practice

(58:56) - The Future of Healthcare with AI

(01:04:26) - Organic Acids Test and Lab Considerations

(01:08:08) - Concluding Thoughts and Recommendations

In this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation.

He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus.

Joe also breaks down the symptoms tied to excess glutamate, from headaches and insomnia to mood swings and neurological issues. He discusses why certain people are more sensitive to glutamate due to genetic differences, and outlines what’s helped him manage it, including specific doses of NAC, glycine, B6, vitamin C, and more.

This episode offers a practical, firsthand look at how glutamate functions, what throws it out of balance, and what can be done to bring it under control.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Timestamps:

(00:00) - Introduction

(00:16) - Understanding Glutamate and Its Effects

(04:32) - Personal Experiments with Glutamate

(08:22) - Supplements and Strategies to Lower Glutamate

(18:31) - Symptoms and Conditions Related to High Glutamate

(20:20) - Genetic Factors and Glutamate

(22:13) - Conclusion

In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing.

Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.

Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy.

The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space.

Whether you’re a health professional or someone trying to optimize your gut, this episode will help you separate science from sales.

📌 Topics covered: microbiome testing technology, bioinformatics, probiotic strains, sequencing methods, red flags in wellness tech

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

(00:00) - Introduction to the Joe Cohen Show

(00:16) - Meet Kiran Krishnan

(01:07) - Understanding Microbiome Testing

(03:01) - The Importance of Whole Genome Sequencing

(04:48) - Challenges in Microbiome and Genetic Testing

(05:42) - Critique of 16S Ribosomal RNA Sequencing

(11:58) - Issues with Viome and Other Testing Companies

(21:14) - Complexities of Microbiome Mapping

(23:27) - Validating Microbiome Tests

(27:04) - The Future of Microbiome Technology

(28:10) - Advancements in Genome Sequencing

(29:18) - Challenges in Microbiome Analysis

(30:40) - Economic Realities of Sequencing

(31:57) - Company Strategies and Ethics

(33:49) - Benefits of Microbiome Testing

(35:12) - Probiotics and Gut Health

(38:20) - Top Probiotic Strains

(43:00) - Importance of Specific Strains

(52:52) - Concluding Thoughts on Probiotics

Most genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants.

In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually takes to do it right.

He shares how SelfDecode analyzes hundreds of thousands (sometimes millions) of variants per report, uses advanced technology to generate more accurate results, and integrates labs and lifestyle data to deliver truly actionable recommendations.

If you've ever wondered whether your DNA test was worth the money, this episode is a must-listen.

- Check out the SelfDecode Report Shop: https://selfdecode.com/shop/

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

(00:00) - Introduction

(00:16) - Overview of Genetic Reports

(01:26) - Competitor Analysis and 100X Series

(02:34) - Detailed Breakdown of Genetic Reports

(03:27) - Recreating Competitor Reports

(08:57) - Final Thoughts

In this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health.

After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company.

Now, Revive DNA is making science-backed, DNA-driven wellness accessible to more people with support from major institutions and powered by OmicsEdge technology.

Tune in for a deep dive into the future of personalized health and what most programs are still getting wrong.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Timestamps:

(00:00) - Introduction

(00:16) - Meet Mark Noten: Founder of Revive DNA

(01:06) - Mark's Journey into the Health Space

(02:09) - A Personal Health Crisis: Mark's Wife's Story

(04:40) - The Role of DNA in Health and Nutrition

(06:44) - Revive DNA: Technology and Partnerships

(11:53) - Revive DNA App: Features and Benefits

(19:31) - Upcoming Sleep Study with Samsung

(28:43) - Future Directions and Closing Remarks

In this episode, Joe discusses the benefits of the probiotic L. Plantarum, specifically the 299V strain. He talks about its effectiveness in reducing gas, improving mood, exercise recovery, and more.

He shares how he personalizes his probiotic routine using SelfDecode, why the specific strain matters more than the brand, and how he takes higher doses to really feel a difference. If you're dealing with gut issues or just want to understand how probiotics can affect things like immunity, allergies, mood, or even homocysteine levels, there’s a lot in here you’ll find useful.

Tune in to learn more about optimizing your health with probiotics and get personalized recommendations from SelfDecode.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Timestamps:

(00:00) - Introduction

(00:16) - Discussing L. Plantarum and Probiotic Recommendations

(01:28) - Joe’s Personal Experiences with Probiotics

(05:28) - Benefits of L. Plantarum

(07:43) - Research and Evidence on L. Plantarum

(09:56) - L. Plantarum's Impact on Various Health Conditions

(12:01) - Probiotics and Skin Health

(13:56) - Probiotics and Metabolic Health

(18:56) - Final Thoughts and Recommendations

Join Joe Cohen in this insightful episode as he interviews Martin Kremmer, CEO and co-founder of BioWatch and FreeAge. Martin, a pioneer in the Danish biohacking scene, shares his company's innovative approach to DNA and epigenetic testing to develop personalized longevity plans.

They discuss the importance of combining different types of data, the future of functional health, and the role of stress management in achieving optimal health. Martin also introduces the Copenhagen Health Week and emphasizes the significance of simple lifestyle changes for long-term health.

Don't miss this comprehensive talk on biohacking, health tech, and much more.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/