The Health Edge: translating the science of self-care

De: Mark Pettus MD and John Bagnulo PhD MPH
  • Resumen

  • “It’s not what we don’t know that gets us into trouble. It’s what we know that ain’t so”.

    Will Rogers


    We believe the explosion of life science research from many disciplines had catapulted ahead of our capacity to process, integrate, understand, and apply. We are interested in translating all that is out there as news to use. A fundamentally different understanding of human biology has emerged. The implications from the perspective of self-care are profound. We are rapidly moving away from the debate of nature versus nurture toward an understanding that life emerges from a dynamic landscape of nature via nurture.

    We are passionate about the science. We are passionate about the implications. We believe in the capacity and possibility made possible by being alive here and now! We are beautifully designed to be on the African Savannah, living fully integrated with our planet, and in the context of social relationship. Our modern environment is not well designed to promote human health and the capacity to thrive. Many are struggling to maintain balance and traction in lives that often feel overwhelming and frightening.The challenge is to better leverage our superb ancestral adaptation for a different and radically challenging modern environment. Everything that touches us today has the potential be be very familiar or totally foreign. The less aware one is of the day to day distance between what we are biologically , as a species, “familiar with” and what we actually encounter, the fewer the possibilities for more effective alignment.

    Leaving one’s health trajectory to chance in our modern environment is a very risky proposition. We are interested in holding the science to the light with an open and humbled mindset. Like you, We are intrepid explorers interested in how we emerge in the midst of our relationship with the environmental inputs of our lives…how we eat, how we move, how we sleep, how we navigate the mind fields of conflict in our lives, how socially connected we are, how we manage the burden of environmental toxins in our lives, how much meaning we cultivate in our work, love, play and how we interpret and respond to stress in our lives. We will drill deep, share all that my experiences has taught and do all that we can to create value for you as you seek to find your health edge. We always welcome your feedback.

    Mark and John

    © 2025 The Health Edge: translating the science of self-care
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Episodios
  • Nourishing the Mind: Food, Light, and Lifestyle for Better Mood
    May 1 2025

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    At a time when anxiety and depression rates are soaring across all age groups, Dr. Mark Pettus cuts through the noise with revelatory insights into how our daily choices shape our mental landscape. This compelling exploration connects the dots between what's on your plate, how you move through your day, and the remarkable resilience of your brain.

    Dr. Pettus introduces the concept of allostatic load—how our bodies interpret and respond to environmental stressors—and reveals why our modern lifestyle creates the perfect storm for mental health challenges. Rather than viewing mood disorders as purely psychological phenomena, he presents compelling evidence that insulin resistance, inflammation, and disrupted circadian rhythms form the physiological foundation of many mental health struggles.

    The conversation takes a fascinating turn when Dr. Pettus explains how rapid blood sugar fluctuations can trigger symptoms indistinguishable from anxiety attacks. That afternoon panic might actually be the aftermath of your lunch choices! Through practical nutritional principles focused on whole foods, lower glycemic options, and nutrient density, he offers actionable strategies to support neuroplasticity—your brain's remarkable ability to generate new cells and neural pathways throughout life.

    Beyond diet, we discover how Brain-Derived Neurotrophic Factor (BDNF)—essentially "miracle grow for the brain"—can be boosted through movement (especially dancing!), natural light exposure, time in nature, and specific foods. The gut-brain connection emerges as another critical pathway, with our microbiome directly influencing neurotransmitter production and mood regulation. Most empowering is the concept of metabolic flexibility—how developing your body's ability to efficiently switch between fuel sources enhances both cognitive function and emotional stability.

    Weaving together ancestral wisdom with cutting-edge neuroscience, Dr. Pettus presents a holistic framework that honors our evolutionary design while navigating modern challenges. This isn't about quick fixes or magic pills—it's about building sustainable resilience through aligned lifestyle choices that activate our innate capacity for wellbeing.

    Ready to rewire your approach to mental health? Listen now and discover how small, strategic shifts in your daily habits can transform your mind, mood, and quality of life. Your brain was designed to thrive—learn how to give it what it truly needs.

    For PowerPoint slide deck: www.thehealthedgepodcast.com

    For Essential Provisions Meals Ready to Eat (MREs): www.essentialprovisions.com

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    32 m
  • Light as Medicine: How Natural Light Cycles Impact Health and Longevity
    Apr 21 2025

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    The rhythms of nature have orchestrated human biology for millennia, but our modern lifestyle has disconnected us from these essential patterns. Dr. Mark Pettus takes us on a fascinating journey through the science of circadian rhythms, revealing how light serves as crucial information that synchronizes every cell in our bodies with the natural day-night cycle.

    From ancient Hippocrates to Nobel Prize-winning research, the evidence is clear: our bodies respond profoundly to light quality and timing. Yet today, we spend over 90% of our time indoors under artificial lighting that bears little resemblance to natural sunlight. This mismatch disrupts our internal clocks and increases risk for depression, anxiety, obesity, diabetes, cardiovascular disease, and even cancer—all conditions that ancestral cultures living in alignment with natural light cycles rarely experienced.

    Dr. Pettus explores how different wavelengths of light trigger specific biological responses. Morning blue light naturally stimulates alertness and cortisol production—precisely what we need to start our day. Evening sunset, with its red-orange spectrum, signals our bodies to reduce cortisol and increase melatonin for restoration and repair. When we expose ourselves to bright blue-rich light after sunset through screens and indoor lighting, we essentially trick our bodies into thinking it's morning, suppressing critical healing processes.

    The good news? Simple changes can dramatically improve circadian alignment. Just 5-10 minutes of morning sunlight exposure helps anchor your biological clock. Using appropriate lighting throughout the day—brighter, cooler lights in morning hours and warmer, dimmer lights after sunset—can mimic natural patterns. These small adjustments yield profound benefits for sleep quality, mood, cognitive performance, and long-term health. Ready to reconnect with the rhythm of life your body was designed to follow?

    Slides and audio can be found at www.thehealthedgepodcast.com
    Essential Provision meals Ready to Eat (MREs) can be found at www.essentialprovisions.com

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    34 m
  • Beyond Ozempic: The Natural Pathways to Enhanced GLP-1 Production
    Apr 8 2025

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    Curious about natural alternatives to expensive GLP-1 medications like Ozempic? Dr. Mark Pettus unveils powerful nutritional strategies to boost your body's own GLP-1 production for improved metabolic health and sustainable weight management.

    This eye-opening presentation dives into the fascinating relationship between your diet, gut microbiome, and GLP-1 production. Dr. Pettus, a kidney and integrative medicine specialist with 40 years of medical experience, explains how quality protein, healthy fats, fiber-rich foods, and even bitter-tasting ingredients can stimulate your natural GLP-1 pathways without prescription medications.

    You'll discover why the timing of your meals and exposure to natural light dramatically impacts hormone production, and how simple lifestyle adjustments can synchronize your circadian rhythms for optimal metabolic health. Dr. Pettus challenges conventional nutritional wisdom with evidence-based perspectives on protein requirements, healthy fats, and the critical importance of preserving muscle mass during weight loss.

    Whether you're currently taking GLP-1 medications and seeking complementary strategies, looking for natural alternatives, or simply interested in optimizing your metabolic health, this webinar provides practical, accessible approaches based on cutting-edge nutritional science. Learn how to work with your body's natural hormonal systems rather than bypassing them, potentially reducing your dependence on expensive pharmaceutical interventions while improving your overall health.

    Take control of your metabolic health through these natural nutritional strategies to enhance your body's own GLP-1 production. Visit Dr. Pettus' website www.thehealthedgepodcast.com for the video and slide deck.

    For amazing GLP-1 inducing meals ready to eat (MREs) from Essential provisions, go to: https://essentialprovisions.com/collections/meals-ready-to-eat-mre

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    41 m
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