The Generalist Podcast Por Mario Gabriele arte de portada

The Generalist

The Generalist

De: Mario Gabriele
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“The future is already here. It’s just not evenly distributed.” The Generalist Podcast brings you weekly conversations with the people who live in these pockets of the future – visionary founders, prescient investors, and original thinkers. Each episode is designed to introduce you to new ideas, technologies, and markets and help you prepare for the world of tomorrow.Mario Gabriele
Episodios
  • How a Solo Founder is Reshaping Global Finance (Parth Garg, CEO of Aspora)

    How a Solo Founder is Reshaping Global Finance (Parth Garg, CEO of Aspora)
    Nov 18 2025
    In the summer of 2022, Parth Garg woke up in Bangalore to discover that his co-founder had fled the country and emailed their investors to tell them their company was dead. Just over three years later, Aspora is one of fintech’s fastest-growing startups. The company, which makes it faster and cheaper for India’s diaspora to send money home and access banking services, now processes close to half a billion dollars in volume every month and has earned a $500 million valuation with backing from elite investors like Hummingbird Ventures, Sequoia, and Greylock.In this conversation, Parth shares his journey from physics prodigy to fintech founder, offering insights into what it really takes to build resilience as a founder and how to create a culture where feedback flows freely, even without a co-founder to provide checks and balances.—We explore:• The moment when Parth discovered his co-founder had left the country and told investors the company was shutting down• How Parth’s childhood moving between cities in India and later to the UAE shaped his adaptability and entrepreneurial mindset• His journey from physics prodigy to startup founder, including early ventures before Aspora• The process of discovering product-market fit through structured experimentation after the initial business model failed• Why the Indian diaspora represents a massive, underserved financial opportunity (1% of the population contributing 30% of deposits)• How stablecoins dramatically reduced Aspora’s working capital requirements and transformed their business model• The regulatory landscape for fintech and crypto in India and the impact of the GENIUS Act in the US• Aspora’s vision to become a comprehensive cross-border bank serving multiple diaspora communities globally—Thank you to the partners who make this possibleGoFundMe Giving Funds: One Account. Zero Hassle.Guru: The AI source of truth for work.Persona: Trusted identity verification for any use case.—Timestamps(00:00) Intro(03:53) How Parth felt when his co-founder fled the country(07:04) Parth’s early days in India and the UAE(09:37) Parth’s love of physics and competitiveness(12:15) The not-so-straightforward path from studying physics at Stanford to entrepreneurship(14:13) Parth’s physics heroes(16:24) The gap year that sparked Parth’s entrepreneurship journey(18:36) Parth’s first startup: selling near-expired groceries(21:58) Moving back to the United States and founding Vance(28:00) Joining YC and finding early backers(31:14) How Parth realized Vance needed to pivot(35:22) How Parth moved forward after his co-founder fled(37:37) Building psychological safety and open debate at Aspora(40:15) How conversations with immigrants inspired Aspora’s idea(45:13) How stablecoins solved Aspora’s biggest operational challenges(46:57) Aspora’s current scale and why India was the perfect starting point(51:34) How Aspora builds loyalty in a low-switching-cost market(52:42) The GENIUS Act and the real opportunity in stablecoins(55:52) The evolution of crypto and stablecoins in India(56:50) The importance of partnerships for scaling Aspora in India(58:18) The next phases of Aspora’s growth(01:00:04) The role of Aspora’s new bets team(1:01:20) Final meditations—Follow Parth GargLinkedIn: https://www.linkedin.com/in/parth29—Resources and episode mentions: https://www.generalist.com/p/banking-the-diaspora-parth-garg—Production and marketing by penname.co. For inquiries about sponsoring the podcast, email jordan@penname.co.
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    1 h y 9 m
  • How Do You Build a New Singapore? Inside Próspera’s Bet on Private Governance | Erick Brimen (Founder and CEO)

    How Do You Build a New Singapore? Inside Próspera’s Bet on Private Governance | Erick Brimen (Founder and CEO)
    Nov 11 2025
    What if you could redesign the rules of society? Not tweak the margins, but start over entirely. That’s the question driving Erick Brimen, founder and CEO of Próspera, a private charter city in Roatán, Honduras. Próspera is a radical experiment in governance: a platform that lets governments and entrepreneurs build cities with new legal systems, regulatory frameworks, and institutions from the ground up. Brimen believes that governance itself can be innovated upon. That cities, like software, can be upgraded. His goal isn’t just to build one new jurisdiction, but to create an operating system for hundreds of prosperous, self-governing communities around the world. In this conversation, Erick and I explore what it really takes to build a modern Singapore from scratch — and why better governance might be humanity’s most powerful lever for progress.Together we explore:• How Brimen’s childhood in Venezuela shaped his understanding of governance and poverty• The historical precedents for charter cities like Dubai, Singapore, and Hong Kong• Why common law, trusted dispute resolution, and dynamic governance are essential foundations• How Próspera’s Governance-as-a-Service model aligns incentives between governments, operators, and residents• The current state of Próspera in Honduras, including its three hubs and economic impact• The political challenges Próspera has faced and how international arbitration has protected the project• Why regulatory innovation enables industries like biotech, crypto, and advanced manufacturing to flourish• How the model could be applied to “catch-up growth,” industry diversification, and accelerating growth in developed nations• The vision for a modern Hanseatic League of charter cities operating on shared governance principles—Thank you to the partners who make this possibleGoFundMe Giving Funds: One Account. Zero Hassle.Guru: The AI source of truth for workTezi: The AI agent for recruiting high-quality candidates quickly.—Transcript: https://www.generalist.com/p/the-170m-experiment-to-build-a-private-city—Timestamps(00:00) Intro(04:10) An overview of Próspera and charter cities(06:43) City of Próspera vs. the platform(08:06) How growing up in Venezuela shaped Erick’s entrepreneurial vision(12:36) The limits of seasteading and why Erick took a different path(15:20) The opposing philosophies that shaped Erick’s path(16:16) The moment that reshaped Erick’s understanding of poverty(19:57) The limits of learning from Dubai, Singapore, and Hong Kong(23:01) Building on the DIFC blueprint(25:12) From Arizona to Honduras: how Próspera built its first city(30:36) Why Honduras won(32:12) Inside the ZEDE framework(36:56) Próspera’s business model(43:45) Conditions on the ground in Honduras(47:14) A quick summary of how it works(48:24) Quick stats on Próspera’s scale and financing(50:47) What years of preparation made possible(52:44) The scale and purpose of Próspera’s three hubs(58:12) Próspera’s 10-year vision(1:01:12) The people Próspera was built to serve(1:04:10) Why less regulation unlocks more innovation(1:05:58) Próspera’s political headwinds(1:12:36) Why Erick remains optimistic that things will work out in Honduras(1:14:44) Addressing criticism of ZEDEs and Próspera(1:18:08) What’s next, and why the U.S. may be the greatest opportunity(1:22:30) Final meditations—Follow Erick BrimenLinkedIn: https://www.linkedin.com/in/erickbrimenWebsite: https://www.erickbrimen.com—Resources and episode mentions: https://www.generalist.com/p/the-170m-experiment-to-build-a-private-city—Production and marketing by penname.co. For inquiries about sponsoring the podcast, email jordan@penname.co.
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    1 h y 24 m
  • Why Psychedelics Might Be the Breakthrough That PTSD Patients Need | Kevin Ryan (The Godfather of NYC Tech)

    Why Psychedelics Might Be the Breakthrough That PTSD Patients Need | Kevin Ryan (The Godfather of NYC Tech)
    Oct 28 2025
    Often called the godfather of NYC tech, Kevin Ryan is one of America’s most influential entrepreneurs and investors. He co-founded MongoDB, Business Insider, Gilt Groupe, Zola, and Transcend Therapeutics, and continues to build and back new companies each year through AlleyCorp. Earlier in his career, he led DoubleClick from a 20-person startup to a global leader, taking it public before its acquisition by Google.In this episode, Kevin shares his insights on two surprising pockets of the future that he’s betting on: psychedelics for mental health and AI-powered materials science. He unpacks how psychedelics are showing remarkable success in treating depression and PTSD, and why AI may discover revolutionary new materials, from helicopter blades to smartphone glass, that humans never imagined possible.We explore:• The promising results of psychedelics in treating depression, PTSD, and addiction• How AI is accelerating materials discovery by exploring combinations humans wouldn’t try• The challenges of building successful incubators and why most attempts fail• How MongoDB lost $1 billion before turning a profit (and why it was worth it)• Why e-commerce businesses like Gilt Groupe often struggle against physical retail• How AlleyCorp plans for the future when shaping its investment strategy• What it really costs society to imprison someone for a year• The hard truth about Europe’s tech ecosystem and why it struggles to compete with the US—Thank you to the partners who make this possibleEnterpret: Transform feedback chaos into actionable customer intelligence.Auth0: Secure access for everyone. But not just anyone.Persona: Trusted identity verification for any use case.—Transcript: https://www.generalist.com/p/why-psychedelics-might-be-the-breakthrough—Timestamps(00:00) Intro(04:30) How Kevin collaborated with Scott Adams(07:11) The origins of AlleyCorp(08:33) The challenge of incubation(10:00) Why intellectual flexibility matters(10:54) What made MongoDB a breakout success(13:49) How shifting market dynamics hurt Gilt’s business(16:22) What Kevin would do differently if he built Gilt again(17:45) Juggling AlleyCorp’s long-term vision with day-to-day demands(20:26) How to make boards more productive(22:25) Why Kevin believes investors should also found companies(24:18) Future spaces Kevin is excited to invest in(25:52) Kevin’s interest in psychedelics and founding Transcend(28:20) Psychedelics for mental health(32:03) How psychedelic therapy is being conducted(34:11) Transcend’s work and the path to approval for methylone(37:47) The challenges of psychedelic research(40:28) How the Trump administration aims to accelerate psychedelic research(41:50) The size and growth of the psychedelic market(44:28) Materials science: What it is, its design tradeoffs, and how AI speeds discovery(49:02) Radical AI’s work creating new compounds(50:34) The industries Radical AI is targeting(52:50) The state of European tech and why it still lags behind(58:26) Final meditations—Follow Kevin RyanLinkedIn: https://www.linkedin.com/in/kevinryan3/X: https://x.com/alley_corp—Resources and episode mentions—Books—• How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence: https://www.amazon.com/Change-Your-Mind-Consciousness-Transcendence/dp/1594204225• Breakneck: China’s Quest to Engineer the Future: https://www.amazon.com/Breakneck-Chinas-Quest-Engineer-Future/dp/1324106034• Why We Sleep: Unlocking the Power of Sleep and Dreams: https://www.amazon.com/Why-We-Sleep-Unlocking-Dreams/dp/1501144324—Episode resources continued at: ⁠https://www.generalist.com/p/why-psychedelics-might-be-the-breakthrough⁠—Production and marketing by penname.co. For inquiries about sponsoring the podcast, email jordan@penname.co.
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    1 h y 8 m
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