Check out the Energy Balance Food Guide here: https://ww.jayfeldmanwellness.com/guide/ Timestamps: 0:00 – intro 1:03 – introducing Andrew Wallen 


1:50 – Andrew’s background in sports, powerlifting, bodybuilding, and Brazilian Jiu-Jitsu 


6:20 – Andrew’s experience cycling through various dietary camps (CICO, paleo, ancestral, carnivore, fasting, low-carb, etc.) 


12:04 – whether we should shape our diets around what our ancestors did 
15:15 – how low-carb, keto, and fasting diets elevated stress and caused blood sugar issues for Andrew 


20:45 – “optimal” blood glucose, HRV, and resting heart rate despite crashing health 


23:50 – how stress-inducing (hormetic) health practices led to binging, self-blame, low brain energy, high blood pressure, and weakened immune function 


27:36 – low-carb, keto, carnivore, fasting, and fear about reintroducing carbs 


33:13 – Andrew’s breaking point with health and what led him to start questioning what being “healthy” really meant 


36:27 –exercise intolerance, fatigue, pre-diabetes, high blood pressure, brain fog, gut issues, slow motility, and poor sleep: the product of years of low-carb and fasting

https://www.jayfeldmanwellness.com/healthy/

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/non-toxic-product-recommendations-for-your-home-body-cookware-skincare-clothing-emfs-more/

Timestamps:

0:00 – intro

0:53 – misconceptions regarding the Randle cycle in the alternative health world

4:57 – what is the Randle cycle?

7:06 – what most people get wrong about the Randle cycle

10:44 – fat oxidation leads to increased ROS production and a decreased NAD+/NADH ratio

16:29 – how fat oxidation inhibits the utilization of carbohydrates

21:03 – the Randle cycle shows the benefits of burning carbs for energy

25:56 – how fat oxidation inhibits the utilization of carbohydrates cont’d

26:57 – metabolic dysfunction, not glucose, drives insulin resistance and aging

32:07 – fat metabolism causes a buildup of citrate which reduces glucose uptake and utilization

38:39 – how glucose oxidation inhibits the uptake and utilization of fats

45:32 – whether you can “activate” or “deactivate” the Randle cycle

47:22 – glucose oxidation leads to an optimal NAD+/NADH ratio and decreased ROS production

52:08 – the protective effects of CO2 and why the brain can’t use fats as a fuel

53:17 – whether we should strive for metabolic flexibility

55:55 – fat metabolism and ketone production as a mechanism for energy conservation and glucose sparing

1:00:02 – insulin resistance as a state of excess fat metabolism and decreasing fat metabolism or stress hormones improves this state

1:05:28 – should we avoid eating carbs and fats together due to the Randle cycle?

1:08:08 – different cells, tissues, and organs can use different fuels at the same time

• How the Randle Cycle actually works

• Whether eating carbs and fats in the same meal causes weight gain and insulin resistance

• The efficiency of using fats as a fuel vs carbohydrate

• How stress impacts fuel usage in the mitochondria

• How to determine the optimal amount of carbs and fats in your diet

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/eb-139-the-truth-about-the-randle-cycle-why-you-can-eat-carbs-and-fats-together/

Timestamps:

0:00 – intro

0:53 – misconceptions regarding the Randle cycle in the alternative health world

4:57 – what is the Randle cycle?

7:06 – what most people get wrong about the Randle cycle

10:44 – fat oxidation leads to increased ROS production and a decreased NAD+/NADH ratio

16:29 – how fat oxidation inhibits the utilization of carbohydrates

21:03 – the Randle cycle shows the benefits of burning carbs for energy

25:56 – how fat oxidation inhibits the utilization of carbohydrates cont’d

26:57 – metabolic dysfunction, not glucose, drives insulin resistance and aging

32:07 – fat metabolism causes a buildup of citrate which reduces glucose uptake and utilization

38:39 – how glucose oxidation inhibits the uptake and utilization of fats

45:32 – whether you can “activate” or “deactivate” the Randle cycle

47:22 – glucose oxidation leads to an optimal NAD+/NADH ratio and decreased ROS production

52:08 – the protective effects of CO2 and why the brain can’t use fats as a fuel

53:17 – whether we should strive for metabolic flexibility

55:55 – fat metabolism and ketone production as a mechanism for energy conservation and glucose sparing

1:00:02 – insulin resistance as a state of excess fat metabolism and decreasing fat metabolism or stress hormones improves this state

1:05:28 – should we avoid eating carbs and fats together due to the Randle cycle?

1:08:08 – different cells, tissues, and organs can use different fuels at the same time

• How glucose and insulin decrease glycation

• Why ketogenic diets can be worse than high-carb diets when it comes to AGE formation

• How autophagy helps to clear AGEs, but increasing autophagy is not the answer

• The true primary drivers of AGE accumulation

• The best diet and supplements for minimizing glycation

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/eb-138-low-carb-diets-increase-glycation-and-what-to-do-instead/

Timestamps:

0:00 – intro

0:57 – how glycation products are detoxified and cleared from the body

4:03 – glycation detoxification is impaired by oxidative stress and inflammation, as seen in type 2 diabetes

7:56 – the benefits of carbohydrates for the detoxification of glycation products

10:42 – the benefits of insulin for the detoxification of glycation products

12:45 – how AGEs are cleared

14:36 – increasing autophagy via hormesis is not the answer for clearing AGEs

19:09 – autophagy can drive disease

20:50 – ATP protects against oxidative stress and allows for proper autophagy when needed

24:37 – impaired mitochondrial along with fatty acid oxidation impairs autophagy and increases oxidative stress

26:54 – carbohydrates do NOT inhibit autophagy

29:18 – adequate thyroid hormone supports proper autophagy

30:15 – adequate ATP and mitochondrial function is needed for the UPS (ubiquitin proteasome system)

32:56 – do high-carb diets actually impair metabolism and insulin sensitivity

35:26 – is fructose really worse for blood sugar regulation and glycation?

37:16 – are low-carb or ketogenic diets the solution to reduce glycation?

40:32 – increased glycation and oxidative stress on ketogenic diets

44:09 –low-carb diets don’t prevent glucose exposure

47:56 – there are still considerable insulin and glucose excursions on low-carb diets

50:06 – gluconeogenesis leads to same glycolytic intermediates as glucose metabolism

51:52 –the main driver of AGE formation and impaired AGE clearance

53:40 – the role of vitamin B1 (thiamine) and mitochondrial energy production in decreasing AGEs

56:27 –endotoxin as a driver of glycation and increased AGE production

58:12 – hypothyroidism as a driver of glycation and AGE accumulation

59:37 – dietary solutions for reducing glycation and AGEs

1:03:33 – how to support the glyoxalase pathway to support the detoxification of glycation products

1:05:56 – avoid calorie restriction, low-carb diets, fasting, resveratrol, cold exposure, excess exercise, and iron overload to decrease glycation and AGEs

1:07:33 – iron as a double-edged sword for oxidative stress

• Why glucose and fructose are not the primary drivers of AGE formation

• Whether blood sugar spikes cause glycation

• How fats and ketones can cause glycation

• What’s really responsible for glycation in type 2 diabetes

• Whether fructose causes more glycation than glucose

Check out the Energy Balance Solution program here: https://www.jayfeldmanwellness.com/solution/

Click here to check out the show notes: https://www.jayfeldmanwellness.com/eb-137-what-really-causes-glycation-is-sugar-really-the-problem/

Timestamps:

0:00 – intro

0:46 – common beliefs about carbohydrates and glycation

2:35 – what are glycation and advanced glycation end products?

6:57 – the process of glycation from glucose

9:30 – is sugar the only source of AGEs?

15:00 – primary drivers of glycation: dicarbonyls

19:30 – how fatty acids, amino acids, and ketones cause AGE formation

21:23 – how increased gluconeogenesis on low-carb diets increases AGE formation

22:53 – glucose metabolism produces very few glycation products in the context of a healthy metabolism

25:33 – omega-6s form AGEs more than 10x faster than glucose

28:24 – the role of ALEs (advanced lipoxidation end products) in glycation and chronic disease

30:36 – whether blood sugar spikes cause glycation

38:52 – whether fructose causes more glycation (or fructation) than glucose

47:05 – can glycation from fructose (fructation) be measured, and does this matter?

52:06 – problems with research looking at fructose’s AGE formation in animal models

• Whether there are benefits to taking massive amounts of glucose for healing
• Whether there is a limit to the amount of glucose we should consume

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Theresa's Instagram: https://www.instagram.com/livingrootswellness/

Timestamps:

0:00 – intro

2:10 – David Stephens’ claim that glucose can't harm you in any way, no matter the amount

7:46 – the difference between glucose and fructose and whether fructose just gets converted to fat

11:13 – whether extreme acidity, alkalinity, and corrosivity are what make substances harmful to humans

15:14 – David Stephens’ claim that sucrose can't cross the blood-brain barrier

18:59 – how authoritarianism shapes the health industry and the difficulties of verifying information with AI

23:14 – whether the “chemical heaviness” of sucrose means that it can’t be helpful in the body

25:51 – whether we agree with David Stephens on the benefits of glucose

29:14 – whether anxiety, irritability, depression, autoimmune disorders, and diabetes are caused by a lack of glucose for your brain

34:37 – what David Stephens misses about the large amounts of glucose he recommends – poor glucose utilization, gut issues, and blood sugar instability

38:06 – whether glucose deficiency is possible and whether most people are eating enough carbs to thrive vs survive

39:04 – David Stephens’ claim that it’s impossible for glucose to be harmful to the body in any way

45:25 – why someone might feel better using large amounts of dextrose as their main carbohydrate source

48:00 – how large quantities of glucose can lead to weight gain, blood sugar spikes, and cardiovascular problems

52:27 – how to avoid dietary extremes and what balance really means

58:41 – weight loss and recovery from mental health issues using a bioenergetic approach

• Andrew Huberman’s ideas about what causes of nighttime wakings and what to do about them
• How to meet all our nutrient needs

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Theresa's Instagram: https://www.instagram.com/livingrootswellness/

Timestamps:

0:00 – intro

0:21 – what Huberman misses when it comes to nighttime wakeups

4:50 – the most common causes of nighttime wakeups and how to resolve them

9:44 –Huberman’s advice to go to sleep earlier is impractical for most people

11:42 – what a healthy sleep schedule looks like and whether running out of melatonin is a concern

13:38 – the relationship between blood sugar and sleep, and whether to have a bedtime snack

16:21 – common drivers of sleep disturbances: gut irritation and elevated stress hormones

19:25 – hidden stressors that could be impacting your sleep: SSRIs, EMFs, devices, and more

22:13 – how to handle unavoidable stressors that interfere with sleep

24:05 – strategies for improving sleep quality and circadian rhythm

26:32 – whether to avoid drinking too many fluids before bed

27:52 – the metabolism-suppressing effects of melatonin and whether supplementing with melatonin is a good idea

29:48 – supplements that may interfere with sleep, and paradoxical reactions that occur while using medications such as SSRIs

33:09 – sleep strategies for shift-workers and recovering from working night shifts

36:33 – the effects of Wi-Fi, EMFs, and dirty electricity on sleep

39:21 – how hormones impact sleep for post-menopausal women

40:54 – evaluating whether supplements are affecting your sleep

44:34 – how low-carb diets impair sleep and increase stress

47:01 – improved thyroid function and weight loss on a bioenergetic approach

48:14 – meeting daily micronutrient needs with food and supplementation

52:57 – how to identify nutrient gaps and excesses

55:37 – which labs to get to gauge micronutrient status and how thiamine (vitamin B1) impacts nutrient absorption

1:00:00 – how concerned should we be with nutrient absorption?

1:03:00 – how anti-nutrients like phytates and oxalates impact nutrient absorption

1:04:37 – navigating different forms of nutrients (non-heme iron vs heme iron, retinol vs beta-carotene, and vitamin K2 vs vitamin K1), and how to know if gut issues are interfering with nutrient absorption

1:07:42 – problems with dietary camps that demonize single nutrients (low vitamin A, low vitamin D, and iron overload)

1:11:24 – how fear and stress deplete critical nutrients

• Whether Dr Ray Peat had it all wrong
• Potential reasons why someone may be bloating from carbs
• How to add carbs back in following restrictive diet

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide

The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/

Theresa's Instagram: https://www.instagram.com/livingrootswellness/

Timestamps:

0:00 – intro

0:32 – Justine Stenger’s claim that Dr Ray Peat had it all wrong

6:15 – did Ray Peat ignore physics, structured water, and light?

11:41 – carbs vs fat: which fuel produces more ROS?

16:50 – Justine Stenger’s claim that carbs act as a crutch for a damaged metabolism, and restoring redox is the solution

21:58 – carbs vs fat: which fuel produces more ATP?

25:27 – conflicting health information on social media and why the “Ray Peat diet” doesn’t work

31:55 – common challenges with implementing Ray Peat’s work

34:09 – Justine Stenger’s mischaracterization of Ray Peat’s work as a “dietary roadmap for people with a broken metabolism”

41:20 – why you shouldn’t outsource critical thinking to social media influencers or AI

45:17 – Ray Peat’s generosity with freely sharing advice and information

46:21 – improvements on a bioenergetic approach without extreme restriction

47:31 – why you may experience bloating from carbs and what to do about it

54:52 – what to do about gut dysbiosis and biofilms

56:56 – how to restore gut health and digestion when transitioning away from keto