Living with myeloma means facing decisions at different points in the journey. One of the biggest moments is the first relapse—when the disease returns after initial treatment.

The good news is that treatment options at first relapse are better and more personalized than ever. One of the most promising is CAR T-cell therapy, which geneticallyengineers a person’s own immune cells to target and destroy myeloma cells. For many patients, it offers the possibility of a deep response, time off therapy, and a chance to regain a sense of normalcy.

In this episode, we’ll explore what receiving CAR T-cell therapy after first relapse looks like—who may be a good candidate, how the process works, what thebenefits and risks are, and what the experience is like for clinicians, patients, and caregivers.

Topics of discussion:

(01:49) When does CAR Tbecome something a patient might hear about?

(03:20) Who may be a goodcandidate

(09:15) How the processworks

(13:39) What theexperience is like for clinicians, patients, and caregivers

This episode is supported by AbbVie, Amgen, Bristol Myers Squibb, Genentech, Johnson & Johnson, Legend Biotech, Pfizer, Regeneron, and Sanofi.

To learn more, download the A Guideto CAR T-Cell Therapy in Myeloma Fast Facts in Myeloma sheet here.

To learn more about multiple myeloma, visit www.themmrf.org.

If you want to learn more about the MMRF’s FREE resources for patients and caregivers, visit the MMRF Education Hub.

If you have additional questions, call our MMRF Patient Navigation Center at 1-888-841- 6673.

Hearing the words “you have multiple myeloma” can be shocking and confusing—learning about the disease and finding the right care team are the most important stepsyou can take after your diagnosis. This episode discusses the importance of seeing a myeloma specialist at a center that treats a high volume of myeloma patients and has an active research program. Newly diagnosed patients, with support from a caregiver, should advocate for themselves by staying informed, asking questions, seeking second opinions if needed, and using credible resources to stay up to date on advances in care.

Topics of discussion:

(04:04) First step after a myeloma diagnosis

(09:36) Caregiver support to help with information overload

(12:31) Finding a myeloma specialist

(19:20) Resources and information

This episode is supported by AbbVie, Amgen, Bristol Myers Squibb, Genentech, Johnson & Johnson, Legend Biotech, Pfizer, Regeneron, and Sanofi.

To learn more about newly diagnosed multiple myeloma, download the Newly Diagnosed Multiple Myeloma booklet here.

To learn more about multiple myeloma, visit ww.themmrf.org.If you want to learn more about the MMRF’s FREE resources for patients and caregivers, visit the MMRF Education Hub.

If you have additional questions, call our MMRF Patient Navigation Center at 1-888-841- 6673.

In part 2, we get practical: planning treatment around family calendars and holidays, deciding between inpatient and outpatient treatment, arranging travel and temporary housing, syncing records between centers, getting financialassistance, and advocating for yourself. With insights from Dr. Joshua Dower (Stamford Health) and lived experiences from myeloma patients Kim and Annie, this episode is your playbook for navigating the details.

Topics of discussion:

(01:13) Navigating travel and scheduling for CAR T-cell therapy

(06:02) Navigating travel and scheduling for bispecific antibody therapy

(09:25) Support from the care team

(11:23) Advocating for the best possible care during transition of care

This episode is supported by Pfizer Inc.

To learn more about bispecific antibody and CAR T-cell therapy, download the Immunotherapy booklet here.

To learn more about multiple myeloma, visit themmrf.org.

To learn more about the MMRF’s FREE resources for patients and caregivers, visit the MMRF Education Hub.

If you have additional questions, call our MMRF Patient Navigation Center at 1-888-841- 6673.