We are joined by behavioral epidemiologist Dr. Kate Wolin to unpack why so many health interventions collapse outside the lab—and what actually drives lasting change in the real world.

From frictionless habit design and daily self-monitoring to movement, sleep, and the muscle-preserving realities of GLP-1s, she reveals the behavioral strategies that truly move the needle on long-term metabolic and overall health.

Watch the full episode to learn how evidence-based behavior science can transform your healthspan.

Learn more about Dr. Kate Wolin:

https://drkatewolin.com/

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Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0

Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com

In this episode, we have Dr. Jennifer Elisseeff joining us to discuss the evolving field of tissue engineering and its applications in regenerative medicine.

She explains the shift from using stem cells to focusing on immune cells for tissue repair, the challenges of regenerating cartilage, and the importance of vascularity in tissue health.

The discussion also covers the impact of aging on tissue repair, the role of senescent cells, and the future of personalized medicine in tissue engineering.

Dr. Elisseeff emphasizes the need for innovative approaches and the integration of immunotherapies to enhance tissue repair processes.

Learn more about Dr. Jennifer Elisseeff:

https://www.bme.jhu.edu/people/faculty/jennifer-h-elisseeff/

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Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0

Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com

Dr. Heidi Tissenbaum, a molecular geneticist at UMass Chan Medical School, joins Dr. Buck Joffrey to explore what C. elegans worms have revealed about the biology of aging.

She explains how these simple organisms helped uncover key longevity pathways—like insulin/IGF-1 signaling and sirtuins—that also exist in humans.

The conversation dives into the balance between stress and resilience, the role of IGF-1 in muscle health and lifespan, and why she believes true longevity breakthroughs will require understanding how the body's systems communicate as a whole.

Learn more about Dr. Heidi Tissenbaum:

https://profiles.umassmed.edu/display/133231

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Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0

Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com