Episodios

  • Eyes In a Dish | Modeling Retinal Development with Pluripotent Stem Cells
    Oct 19 2025

    How lab-grown mini-retinas model human vision. In this episode, we show how iPSC-derived retinal organoids form layered photoreceptors, enable gene-editing tests (CRISPR, ASOs), and accelerate drug screening for inherited retinal diseases. Clear takeaways, visuals, and translational notes for bench and clinic. Educational only; not medical advice.


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    18 m
  • Nobel Winning Breakthrough: Unpacking Peripheral Immune Tolerance | GeneInCell
    Oct 12 2025

    How FOXP3-defined Tregs prevent autoimmunity and shape therapy. We trace the discoveries by Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi, unpack Treg biology and assays, and explore translational angles—from autoimmune disease and transplantation to cancer immunotherapy and engineered Tregs. Educational content only; not medical advice.

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    15 m
  • 🧬 CRISPR dCas9 Activation Systems for Gene Regulation | GeneInCell | 2025
    Oct 5 2025

    How do you turn genes on with CRISPR—without making a single cut? This episode breaks down dCas9-based activators (VP64, p300, SAM, VPR, SunTag), guide design near promoters/enhancers. We compare strengths, limits, and off-target risks. Clear takeaways on assays (qPCR, RNA-seq, ATAC-seq, reporter readouts), durability, and safety considerations for translational work. Educational only; not medical advice.

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    17 m
  • Gene Knockout: From Lab to Therapy | GeneInCell | 2025
    Sep 29 2025

    In this episode, we explore how turning off defective genes is becoming a crucial aspect of modern medicine.

    Educational only; not medical advice.

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    19 m
  • Antisense Oligonucleotides: From Sequence to Therapy
    Sep 21 2025

    Dive into the fascinating world of antisense oligonucleotides (ASOs) with this insightful podcast series. Explore the journey from genetic sequencing to groundbreaking therapeutic applications, uncovering how these innovative molecules are transforming the treatment of genetic disorders and beyond. Hosted by experts from GeneInCell, this series blends cutting-edge science with real-world impact, offering a deep dive into the future of precision medicine. Tune in to stay ahead in the evolution of human health!Educational content only; not medical advice.

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    26 m
  • AI's Impact on Biology and Drug Discovery | GeneInCell | 2025
    Sep 14 2025

    How modern AI is rewiring the life-science stack—from target discovery to first-in-human. This episode unpacks foundation models for proteins/RNAs, generative chemistry, AI-guided ADMET/PK, phenotypic screening on organoids with high-content imaging, multi-omics integration, and self-driving labs with active learning. We compare what’s hype vs. real, walk through validation loops (prospective wet-lab tests, reproducibility, bias control), and map the path to clinic and regulation. Case studies highlight wins and failures—and where AI can truly compress timelines and costs.Educational content only; not medical advice

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    1 h y 11 m
  • Spaceflight vs. Your Body- Why Vision Suffers
    Sep 7 2025

    This episode spotlights Spaceflight-Associated Neuro-Ocular Syndrome (SANS)—a major risk where microgravity-driven fluid shifts raise eye/brain pressure, leading to optic nerve swelling and vision changes. Beyond SANS, we examine the full spectrum of space eye hazards: corneal abrasions from lunar/planetary dust, chemical burns, infections, and radiation effects. Educational content only; not medical advice.


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    19 m
  • The American Biotech Landscape: Investment, Innovation, and Hubs
    Sep 6 2025

    We map the transition of science into companies in the USA. Hear how funding cycles, NIH/SBIR grants, talent pipelines, universities, CDMOs, and clinical-trial access shape each hub. Educational only; not investment advice.


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    43 m