GeneInCell Podcast Por Vinod Reddy Lekkala arte de portada

GeneInCell

GeneInCell

De: Vinod Reddy Lekkala
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GeneInCell-The AI-powered Biotech Podcast focuses on crisp, science-based podcasts on stem cells, organoids, and gene editing—tracking breakthroughs from bench to bedside for better human health, including Biotech and business.Vinod Reddy Lekkala Ciencia Ciencias Biológicas
Episodios
  • Eyes In a Dish | Modeling Retinal Development with Pluripotent Stem Cells

    Eyes In a Dish | Modeling Retinal Development with Pluripotent Stem Cells
    Oct 19 2025

    How lab-grown mini-retinas model human vision. In this episode, we show how iPSC-derived retinal organoids form layered photoreceptors, enable gene-editing tests (CRISPR, ASOs), and accelerate drug screening for inherited retinal diseases. Clear takeaways, visuals, and translational notes for bench and clinic. Educational only; not medical advice.
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    18 m
  • Nobel Winning Breakthrough: Unpacking Peripheral Immune Tolerance | GeneInCell

    Nobel Winning Breakthrough: Unpacking Peripheral Immune Tolerance | GeneInCell
    Oct 12 2025

    How FOXP3-defined Tregs prevent autoimmunity and shape therapy. We trace the discoveries by Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi, unpack Treg biology and assays, and explore translational angles—from autoimmune disease and transplantation to cancer immunotherapy and engineered Tregs. Educational content only; not medical advice.
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    15 m
  • 🧬 CRISPR dCas9 Activation Systems for Gene Regulation | GeneInCell | 2025

    🧬 CRISPR dCas9 Activation Systems for Gene Regulation | GeneInCell | 2025
    Oct 5 2025

    How do you turn genes on with CRISPR—without making a single cut? This episode breaks down dCas9-based activators (VP64, p300, SAM, VPR, SunTag), guide design near promoters/enhancers. We compare strengths, limits, and off-target risks. Clear takeaways on assays (qPCR, RNA-seq, ATAC-seq, reporter readouts), durability, and safety considerations for translational work. Educational only; not medical advice.
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    17 m
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