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Cardiology Today

Cardiology Today

De: Deconstructed Cardiology
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Stay current with cardiovascular medicine without the time commitment. Every morning, we deliver concise audio summaries of the latest original research from top cardiology journals. Top 5 breakthrough studies briefed in under 5 minutes (perfect for your commute or between patients). PubMed links included for full articles. Perfect for cardiologists, cardiothoracic surgeons, cardiac nurses, researchers, and healthcare workers who need to stay informed but lack time to scan multiple journals daily. For educational and reference purposes only. Not intended as medical advice.© 2025 Deconstructed Cardiology LLC Ciencia Higiene y Vida Saludable
Episodios
  • I. C. D. Driving Risk Predicted by Baseline Data. 01/11/26

    I. C. D. Driving Risk Predicted by Baseline Data. 01/11/26
    Jan 11 2026
    Welcome to Cardiology Today – Recorded January 11, 2026. This episode summarizes 5 key cardiology studies on topics like left ventricular ejection fraction and Implantable cardioverter-defibrillator. Key takeaway: I. C. D. Driving Risk Predicted by Baseline Data.. Article Links: Article 1: Sensitization in Organ Transplantation: Assessment of Risk (STAR) 2025 Meeting Group Report. (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons) Article 2: Phenotypic stratification and prognostic value of cardiac magnetic resonance in non-dilated left ventricular cardiomyopathy. (Heart (British Cardiac Society)) Article 3: Predicting the risk of motor vehicle crash in the first year after cardioverter-defibrillator implantation. (Heart (British Cardiac Society)) Article 4: Early predictors of aortic valve surgery in patients with significant bicuspid aortic regurgitation without initial surgical indication. (Heart (British Cardiac Society)) Article 5: Insomnia symptom trajectories and incident cardiovascular disease in older adults: a longitudinal cohort study. (Heart (British Cardiac Society)) Full episode page: https://podcast.explainheart.com/podcast/i-c-d-driving-risk-predicted-by-baseline-data-01-11-26/ Featured Articles Article 1: Sensitization in Organ Transplantation: Assessment of Risk (STAR) 2025 Meeting Group Report. Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41519473 Summary: The S. T. A. R. initiative’s working group has held three consensus meetings and published reports that have influenced clinical care in organ transplantation. The 2025 group identified and addressed five key evolving areas in transplantation: donor-derived cell-free D. N. A. tests, innate immunity in allograft rejection, immunogenicity and antigenicity, and H. L. A. antibody quantification. This demonstrates the group’s ongoing work in translating laboratory data into clinical practice and guiding future research priorities. Article 2: Phenotypic stratification and prognostic value of cardiac magnetic resonance in non-dilated left ventricular cardiomyopathy. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40819904 Summary: This study identified three distinct cardiac magnetic resonance-based phenotypes in 515 patients with non-dilated left ventricular cardiomyopathy. These phenotypes include late gadolinium enhancement positive with preserved left ventricular ejection fraction, late gadolinium enhancement negative with dilated left atrium or right ventricle and preserved left ventricular ejection fraction, and late gadolinium enhancement negative with isolated systolic dysfunction with preserved left ventricular ejection fraction. The classification of these phenotypes provides a new framework for risk stratification in this patient population. Article 3: Predicting the risk of motor vehicle crash in the first year after cardioverter-defibrillator implantation. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40555466 Summary: This study utilized 22 years of population-based administrative data to identify licensed drivers who received a first implantable cardioverter-defibrillator between 1998 and 2018. It developed a method using baseline health and driving data, along with logistic regression, to estimate the risk of motor vehicle crash in the first year post-implantation. This approach provides clinicians with a tool to personalize medical driving restrictions following implantable cardioverter-defibrillator implantation. Article 4: Early predictors of aortic valve surgery in patients with significant bicuspid aortic regurgitation without initial surgical indication. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40541293 Summary: This study identified a cohort of 335 patients with moderate or severe bicuspid aortic regurgitation who did not initially meet guideline-based criteria for aortic valve surgery. These patients were drawn from a single-center registry of 1927 individuals with bicuspid aortic valve, excluding those with severe aortic stenosis, endocarditis, or other major valvular diseases. The study establishes the critical need for identifying early predictors of disease progression within this specific high-risk subgroup to aid in optimal risk stratification and surgical timing. Article 5: Insomnia symptom trajectories and incident cardiovascular disease in older adults: a longitudinal cohort study. Journal: Heart (British Cardiac Society) PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40425274 Summary: This longitudinal cohort study of 12000 participants aged 50 years or older investigated the associations between insomnia symptoms, their long-term ...
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  • HoFH Therapy: New Drug Bypasses LDL Receptor 01/10/26

    HoFH Therapy: New Drug Bypasses LDL Receptor 01/10/26
    Jan 10 2026
    Welcome to Cardiology Today – Recorded January 10, 2026. This episode summarizes 5 key cardiology studies on topics like SHR-1918 and clinical outcomes. Key takeaway: HoFH Therapy: New Drug Bypasses LDL Receptor. Article Links: Article 1: Congenital heart defects: familial recurrence patterns in Sweden. (European heart journal) Article 2: Cardiovascular adaptation to training load in endurance athletes: a longitudinal study. (European heart journal) Article 3: Serial Assessment of Modified SCAI SHOCK Classification in Post-Cardiotomy Patients. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation) Article 4: Anti-ANGPTL3 Antibody SHR-1918 for Homozygous Familial Hypercholesterolemia: A Nonrandomized Clinical Trial. (JAMA cardiology) Article 5: Social Determinants of Health and Clinical Outcomes in Hypertrophic Cardiomyopathy. (JAMA cardiology) Full episode page: https://podcast.explainheart.com/podcast/hofh-therapy-new-drug-bypasses-ldl-receptor-01-10-26/ Featured Articles Article 1: Congenital heart defects: familial recurrence patterns in Sweden. Journal: European heart journal PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41504464 Summary: Congenital heart defects aggregate in families, necessitating updated population-based recurrence estimates due to improved survival and diagnostic precision. A comprehensive retrospective population-based case-control study utilized nationwide Swedish register data. This investigation included 51778 individuals diagnosed with congenital heart defects born between 1987 and 2001. The study established the specific familial recurrence patterns for congenital heart defects within the Swedish population. Article 2: Cardiovascular adaptation to training load in endurance athletes: a longitudinal study. Journal: European heart journal PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41499247 Summary: The study demonstrated cardiovascular adaptation to training load in endurance athletes, linking objectively quantified exercise duration and intensity to cardiac magnetic resonance findings. Researchers correlated heart rate monitor data with cardiac magnetic resonance results in 69 young male endurance athletes, aged 16 to 23 years, and 82 middle-aged male endurance athletes, aged 45 to 70 years. This approach provided a precise characterization of exercise-induced cardiac remodeling, overcoming the limitations of previous studies that relied on self-reported data. It directly showed specific cardiac structural and functional changes in response to measured training loads. Article 3: Serial Assessment of Modified SCAI SHOCK Classification in Post-Cardiotomy Patients. Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41513116 Summary: Post-cardiotomy shock is a severe complication after cardiac surgery, linked to high in-hospital mortality. The Society for Cardiovascular Angiography and Interventions SHOCK classification provides a valid approach for initial shock staging post-surgery. This study externally validated the prognostic value and accuracy of serial Society for Cardiovascular Angiography and Interventions SHOCK reclassification for all-cause in-hospital mortality. The data confirmed that repeated application of the classification offers improved risk assessment and predicts outcomes in post-cardiotomy patients. Article 4: Anti-ANGPTL3 Antibody SHR-1918 for Homozygous Familial Hypercholesterolemia: A Nonrandomized Clinical Trial. Journal: JAMA cardiology PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41499141 Summary: Homozygous familial hypercholesterolemia is a rare, life-threatening genetic disorder resulting in markedly elevated low-density lipoprotein cholesterol levels due to absent or severely impaired low-density lipoprotein receptor activity. Traditional lipid-regulating agents are largely ineffective as their activity relies on residual low-density lipoprotein receptor function. This nonrandomized clinical trial demonstrated that the anti-angiopoietinlike 3 antibody SHR-1918 reduced lipid levels through a low-density lipoprotein receptor-independent pathway. The study confirmed SHR-1918 as a viable therapeutic option for homozygous familial hypercholesterolemia, addressing a critical unmet need. Article 5: Social Determinants of Health and Clinical Outcomes in Hypertrophic Cardiomyopathy. Journal: JAMA cardiology PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41499131 Summary: Area-based indicators of social determinants of health are associated with higher risk for acquired heart disease. This multicenter, prospective cohort study demonstrated the association of these area-based social determinants of health with clinical outcomes in patients with hypertrophic cardiomyopathy. The study, involving US adult patients with hypertrophic cardiomyopathy from 5 ...
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  • A. I. for Continuous Q. T. Monitoring 01/09/26

    A. I. for Continuous Q. T. Monitoring 01/09/26
    Jan 10 2026
    Welcome to Cardiology Today – Recorded January 09, 2026. This episode summarizes 5 key cardiology studies on topics like MTEER and transcatheter interventions. Key takeaway: A. I. for Continuous Q. T. Monitoring. Article Links: Article 1: 2026 ACC/AHA Clinical Performance and Quality Measures for Patients With Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures. (Journal of the American College of Cardiology) Article 2: Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation. (Circulation) Article 3: Air pollution, meteorological factors, and cardiac remodelling in children: a multi-omics cohort study. (European heart journal) Article 4: VENOPULMONARY EXTRACORPOREAL LIFE SUPPORT: AN ELSO REGISTRY ANALYSIS. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation) Article 5: Contemporary Operator Procedural Volumes and Outcomes for TAVR and MTEER in the US. (JAMA cardiology) Full episode page: https://podcast.explainheart.com/podcast/a-i-for-continuous-q-t-monitoring-01-09-26/ Featured Articles Article 1: 2026 ACC/AHA Clinical Performance and Quality Measures for Patients With Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures. Journal: Journal of the American College of Cardiology PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41505788 Summary: C. C. / A. H. A. Clinical Performance and Quality Measures for Patients With Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Performance Measures. The 2026 American College of Cardiology/American Heart Association Clinical Performance and Quality Measures for Patients With Peripheral Artery Disease provide guidance for clinicians, researchers, and quality assurance personnel. These measures establish standards for assessing the effects of treatment decisions, including specific medications and diagnostic tests for individuals with peripheral artery disease. They serve to standardize care and facilitate quality assurance in clinical practice and research for this patient population. Article 2: Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation. Journal: Circulation PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41460938 Summary: T. Monitoring to Identify High-Risk Prolongation Events After Class Three Antiarrhythmic Initiation. A deep learning system called 3DRECON-QT was developed for continuous Q. T. monitoring to identify high-risk Q. T. prolongation events. This system addresses drug-induced Q. T. prolongation that can occur after initiation of class three antiarrhythmics during outpatient care. 3DRECON-QT reconstructs spatial information from a single lead vector to quantify Q. T. and Q. T. corrected intervals. Its development provides a novel approach for identifying high-risk Q. T. prolongation, overcoming limitations of current insertable cardiac monitors. Article 3: Air pollution, meteorological factors, and cardiac remodelling in children: a multi-omics cohort study. Journal: European heart journal PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41511488 Summary: A multi-omics cohort study investigates the effects of air pollution and meteorological factors on cardiac remodeling in children. A total of 2029 children were enrolled in the Southwest Health Children Cohort in China to provide crucial data on these exposures. This research illuminates how environmental factors influence cardiovascular structure and function and the underlying biomolecular mechanisms in pediatric populations. The study addresses a critical knowledge gap regarding these effects in children, contrasting with established associations in adults. Article 4: VENOPULMONARY EXTRACORPOREAL LIFE SUPPORT: AN ELSO REGISTRY ANALYSIS. Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41506589 Summary: L. S. O. Registry Analysis. This Extracorporeal Life Support Organization registry analysis provides real-world outcomes for adults receiving venopulmonary extracorporeal life support. The study utilized a large sample size from the E. L. S. O. registry to describe patient experiences across various clinical conditions. It establishes data regarding the current use, adverse events, and prognostic drivers for venopulmonary extracorporeal life support, where previous information was limited. Article 5: Contemporary Operator Procedural Volumes and Outcomes for TAVR and MTEER in the US. Journal: JAMA cardiology PubMed Link: https://pubmed.ncbi.nlm.nih.gov/41505119 Summary: S. This cohort study investigated...
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